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Source: Frontiers in Neurology

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Total 2557 results found since Jan 2013.

The role of neurophysiological tools in the evaluation of ischemic stroke evolution: a narrative review
Ischemic stroke is characterized by a complex cascade of events starting from vessel occlusion. The term “penumbra” denotes the area of severely hypo-perfused brain tissue surrounding the ischemic core that can be potentially recovered if blood flow is reestablished. From the neurophysiological perspective, there are local alterations—reflecting the loss of function of the core and the penumbra—and widespread changes in neural networks functioning, since structural and functional connectivity is disrupted. These dynamic changes are closely related to blood flow in the affected area. However, the pathological proces...
Source: Frontiers in Neurology - April 27, 2023 Category: Neurology Source Type: research

Safety and efficacy of endovascular recanalization for symptomatic non-acute atherosclerotic intracranial large artery occlusion
ConclusionThis study suggests that interventional recanalization may be a feasible, basically safe, and an effective alternative in carefully selected patients with symptomatic non-acute atherosclerotic ILAO who have failed medical management.
Source: Frontiers in Neurology - April 27, 2023 Category: Neurology Source Type: research

Fallers after stroke: a retrospective study to investigate the combination of postural sway measures and clinical information in faller ’s identification
ConclusionA model combining BBS, BI, and SwayML was best at identifying faller status in persons in the chronic phase post stroke. When balance performance is poor, a high SwayML may be part of a strategy protecting from falls.
Source: Frontiers in Neurology - April 27, 2023 Category: Neurology Source Type: research

Endovascular thrombectomy is cost-effective in acute basilar artery occlusion stroke
ConclusionEndovascular treatment is cost-effective in patients with aBAO stroke.
Source: Frontiers in Neurology - April 26, 2023 Category: Neurology Source Type: research

Surface EMG analysis of weakness distribution in upper limb muscles post-stroke
This study aims to depict weakness distribution among forearm muscles given that joints in the upper limb are usually driven by a group of muscles. Multi-channel electromyography (EMG) was applied to assess the muscle group, and an EMG-based index was proposed to quantify the weakness of individual muscles. By using this method, four weakness distribution patterns were observed in extensor muscles from five out of eight subjects after stroke. Complex weakness distribution patterns were observed in flexor muscles from seven out of the eight subjects when they performed grasp, tripod pinch, and hook grip. The findings can he...
Source: Frontiers in Neurology - April 25, 2023 Category: Neurology Source Type: research

Delayed low cerebellar perfusion status is associated with poor outcomes in top-of-basilar occlusion treated with thrombectomy
ConclusionWe found that initial perfusion delay proximal to TOB in the low cerebellum might be a predictor for poor functional outcomes in TOB treated with MT.
Source: Frontiers in Neurology - April 25, 2023 Category: Neurology Source Type: research

Research advances in imaging markers for predicting hematoma expansion in intracerebral hemorrhage: a narrative review
ConclusionThe management of ICH presents a significant challenge, and identifying high-risk patients for HE is crucial to improving outcomes. The use of imaging markers for HE prediction can aid in the rapid identification of such patients and may serve as potential targets for anti-HE therapies in the acute phase of ICH. Therefore, further research is needed to establish the reliability and validity of these markers in identifying high-risk patients and guiding appropriate treatment decisions.
Source: Frontiers in Neurology - April 25, 2023 Category: Neurology Source Type: research

Trimethylamine-N-oxide: a potential biomarker and therapeutic target in ischemic stroke
This article reviews the production of TMAO, TMAO’s relationship with different etiological types of ischemic stroke, and the possibility of reducing TMAO levels to improve the prognosis of ischemic stroke.
Source: Frontiers in Neurology - April 21, 2023 Category: Neurology Source Type: research

Functionality and quality of life in Brazilian patients 6 months post-stroke
ConclusionThis research found no relationship between activities performed before the stroke and functionalities and quality of life after the stroke, but comorbidities and extended hospital stay were associated with worse outcomes.
Source: Frontiers in Neurology - April 20, 2023 Category: Neurology Source Type: research

Clinical value of the systemic immune-inflammation index in moyamoya disease
ConclusionBased on the results of this study, patients with moyamoya disease admitted for inpatient care due to acute or chronic stroke have significantly higher SII, NLR, and PLR when compared to blood samples drawn from completely healthy controls in a non-emergent outpatient setting. While the findings may suggest that inflammation plays a role in moyamoya disease, further studies are warranted to corroborate such an association. In the middle stage of moyamoya disease, there may be a more intense imbalance of immune inflammation. Further studies are needed to determine whether the SII index contributes to the diagnosis...
Source: Frontiers in Neurology - April 20, 2023 Category: Neurology Source Type: research

The effect and safety of constraint-induced movement therapy for post-stroke motor dysfunction: a meta-analysis and trial sequential analysis
ConclusionCIMT may be an optional and safe rehabilitation therapy to improve PSMD. However, due to limited studies, the optimal protocol of CIMT for PSMD was undetermined, and more RCTs are required for further exploration.Clinical trial registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=143490, identifier: CRD42019143490.
Source: Frontiers in Neurology - April 18, 2023 Category: Neurology Source Type: research

Current status of endovascular treatment for older adults with acute large vessel occlusion stroke in China: subgroup analysis of ANGEL act registry
ConclusionWe found that patients less than or greater than 80 years of age share similar clinical outcomes, without increasing the risk of ICH and mortality.
Source: Frontiers in Neurology - April 18, 2023 Category: Neurology Source Type: research

Diaphragmatic ultrasound can help evaluate pulmonary dysfunction in patients with stroke
ConclusionWe found that patients with stroke had pulmonary dysfunction even in the recovery period. Diaphragmatic ultrasound can be used as a simple and effective tool for detecting pulmonary dysfunction in patients with stroke, with TdiFVC being the most effective index.
Source: Frontiers in Neurology - April 18, 2023 Category: Neurology Source Type: research

A non-linear relationship between lesion length and risk of recurrent cerebral ischemia after stenting for symptomatic intracranial stenosis with hemodynamic impairment
ConclusionA non-linear relationship exists between lesion length and RCI after stenting for sICAS with HI. The lesion length increases the overall risk of RCI for BES and for SES when the length was <9.00 mm, while no significant relationship was found when the length was >9.00 mm for SES.
Source: Frontiers in Neurology - April 18, 2023 Category: Neurology Source Type: research

Serum homocysteine level is an independent risk factor for 1-year stroke recurrence in patients with acute ischemic stroke and H-type hypertension: results from the Xi'an stroke registry study of China
ConclusionsIn patients with AIS and H-type hypertension, the serum homocysteine level was an independent risk factor for 1-year stroke recurrence. A serum homocysteine level of ≥25 μmol/L significantly increased the risk of 1-year stroke recurrence. These findings can inform the creation of a more precise homocysteine reference range for the prevention and treatment of 1-year stroke recurrence in patients with AIS and H-type hypertension and provide a theoretical foundation for the individualized prevention and treatment of stroke recurrence.
Source: Frontiers in Neurology - April 18, 2023 Category: Neurology Source Type: research