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Clinical narratives as a predictor for prognosticating functional outcomes after intracerebral hemorrhage
This study aimed to investigate whether clinical narratives can improve the performance for predicting functional outcomes after ICH.
Source: Journal of the Neurological Sciences - September 12, 2023 Category: Neurology Authors: Ling-Chien Hung, Ying-Ying Su, Jui-Ming Sun, Wan-Ting Huang, Sheng-Feng Sung Source Type: research

Factors associated with hemorrhagic transformation after endovascular treatment despite early recanalization
To identify new factors associated with hemorrhagic transformation (HT) despite early recanalization in patients with acute ischemic stroke treated with mechanical thrombectomy.
Source: Journal of the Neurological Sciences - August 30, 2023 Category: Neurology Authors: Antonio Ciacciarelli, Agostino Tessitore, Giulia Fiume, Carmelo Tiberio Curr ò, Alessandra Coglitore, Anna Gardin, Fabrizio Giammello, Francesco Grillo, Mirta Longo, Enrico Mormina, Concetto Fabio Vecchio, Davide Vicari, Rosa Fortunata Musolino, Antonio Source Type: research

Significant increase in mortality and risk of acute ischemic stroke in infective endocarditis patients with subarachnoid hemorrhage secondary to mycotic aneurysms
Infective Endocarditis (IE) patients are known to have a variety of complications with one of the rarest, but serious being cerebral mycotic aneurysm, which can result in subarachnoid hemorrhage (SAH). Using the National In-Patient Sample database, we sought to determine the rate of acute ischemic stroke (AIS) and outcomes in IE- patients with and without SAH. In total, we identified 82,844  IE-patients from 2010 to 2016, of which 641 had a concurrent diagnosis of SAH. IE patients with SAH had a more complicated course, higher mortality rate (OR 4.65 CI 95% 3.9–5.5, P 
Source: Journal of the Neurological Sciences - May 10, 2023 Category: Neurology Authors: Tolga Sursal, Kevin Clare, Eric Feldstein, Jonathan Ogulnick, Bridget Nolan, Zafar Karimov, Andrew Nazarenko, Linda Ye, Yarden Bornovski, Serena Wong, Joshua Goldberg, Stephan A. Mayer, Andrew Bauerschmidt, Marc Y. El Khoury, Hosam Al-Jehani, Chirag D. Ga Source Type: research

Association of hyperglycemia and computed tomographic perfusion deficits in patients who underwent endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion: A subgroup analysis of a randomized phase 3 trial (MR CLEAN)
Hyperglycemia is highly prevalent in patients with acute ischemic stroke and is associated with increased risk of symptomatic intracranial hemorrhage, larger infarct size and unfavorable outcome. Furthermore, glucose may modify the effect of endovascular treatment (EVT) in patients with ischemic stroke. Hyperglycemia might lead to accelerated conversion of penumbra into infarct core. However, it remains uncertain whether hyperglycemia on admission is associated with the size of penumbra or infarct core in acute ischemic stroke.
Source: Journal of the Neurological Sciences - June 30, 2022 Category: Neurology Authors: C.J.B.A. Kersten, A.A.M. Zandbergen, O.A. Berkhemer, J. Borst, M. Haalboom, Y.B.W.E.M. Roos, D.W.J. Dippel, R.J. van Oostenbrugge, A. van der Lugt, W.H. van Zwam, C.B. Majoie, H.M. den Hertog, on behalf of the MR CLEAN investigators Source Type: research

Apolipoprotein E genotypes in stroke patients from urban Tanzania
Stroke disproportionately affects low- and middle-income countries (LMICs) with an increasing burden in Sub-Saharan African populations, who are undergoing an epidemiological transition. The ε2 and ε4 gene variants of apolipoprotein E (ApoE) are each linked to an increased risk of intracerebral hemorrhage [1], although the mechanisms of this association are not well understood. There also appear to be connections between ischemic stroke and ApoE gene variants, especially ε4, although these are less established [2].
Source: Journal of the Neurological Sciences - June 25, 2022 Category: Neurology Authors: Dylan R. Rice, Andre C. Vogel, Seif S. Ismail, Kigocha Okeng'o, Grace K. Lugemwa, Jonathan Henry, Christina Kourkoulis, Farrah J. Mateen Source Type: research

Associations between stroke type, stroke severity, and pre-stroke osteoporosis with the risk of post-stroke fracture: A nationwide population-based study
BackgroundRecognizing the post-stroke fracture risk factors is crucial for targeted intervention and primary fracture prevention. We aimed to investigate whether stroke types, stroke severity, and pre-stroke osteoporosis are associated with post-stroke fracture.MethodsIn a nationwide cohort, we identified previously fracture-free patients who suffered from first-ever stroke, either acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH), between 2003 and 2015. Information regarding stroke severity, osteoporosis, comorbidity, and medication information was collected.
Source: Journal of the Neurological Sciences - May 27, 2021 Category: Neurology Authors: Hung-Ping Wang, Sheng-Feng Sung, Hsin-Yi Yang, Wan-Ting Huang, Cheng-Yang Hsieh Source Type: research

Impact of acetylsalicylic acid (ASA) on postoperative hemorrhage in spinal lumbar surgery: Should preoperative ASA be discontinued for elective surgery?
This study aimed to analyze the risk of bleeding by applying ASA before lumbar spinal surgery.
Source: Journal of the Neurological Sciences - May 22, 2021 Category: Neurology Authors: Ali Rashidi, Fabian Leins, I. Erol Sandalcioglu, Michael Luchtmann Source Type: research

Safety and efficacy of antiplatelet use before intravenous thrombolysis for acute Ischemic stroke
To study the effects of pretreatment with Antiplatelet (AP) before IV thrombolysis (IVT) on the rate of symptomatic intracranial hemorrhage (sICH) and functional outcome in patients with Acute Ischemic stroke (AIS).
Source: Journal of the Neurological Sciences - April 15, 2021 Category: Neurology Authors: Ashkan Mowla, Maryam Sharifian-Dorche, Sandhya Mehla, Navdeep S. Lail, Amirhossein Sharifian-Dorche, Caila B. Vaughn, Robert N. Sawyer, Peyman Shirani Source Type: research

Reply to the letter to the editor regarding “predictors and outcomes of hemorrhagic stroke in reversible cerebral vasoconstriction syndrome”
First, we thank the author of the letter for their interest and comments regarding our article [1]. Our study was focused on delineating the differential risk factors and clinical outcomes of hemorrhagic reversible cerebral vasoconstriction syndrome (RCVS). We found that intracranial hemorrhage was common among patients hospitalized due to RCVS and its occurrence was clearly associated with worse clinical outcomes.
Source: Journal of the Neurological Sciences - March 27, 2021 Category: Neurology Authors: Aayushi Garg, Santiago Ortega-Gutierrez Tags: Response to letter to the Editor Source Type: research

Re: Predictors and outcomes of hemorrhagic stroke in reversible cerebral vasoconstriction syndrome (Garg et al., Volume 421, 117312, February 15, 2021)
Dear Editor,
Source: Journal of the Neurological Sciences - March 27, 2021 Category: Neurology Authors: Aneesh B. Singhal Tags: Letter to the Editor Source Type: research

Atherosclerotic event risk and risk reduction therapies among Ghanaian hemorrhagic stroke survivors
Intracerebral hemorrhage (ICH) stroke constitute up to 40% of incident strokes in Africa. While ICH patients are at high risk for atherosclerotic events, the risk-benefit of anti-atherosclerotic therapies in this patient population is uncertain.
Source: Journal of the Neurological Sciences - March 9, 2021 Category: Neurology Authors: Fred Stephen Sarfo, Sheila Adamu, Vida Obese, Manolo Agbenorku, Priscilla Abrafi Opare-Addo, Bruce Ovbiagele Source Type: research

Delayed-onset motor aphasia succeeds Holmes' tremor and neuropathic pain after left thalamic hemorrhage
Although most neurological symptoms related to cerebrovascular diseases appear immediately after the events, some delayed-onset neurological symptoms, such as Holmes' tremor or central post-stroke pain (CPSP), can occur after a certain period of time [1]. The alterations in the neural networks caused by maladaptative neuroplasticity have been hypothesized to underlie this pathophysiology [2]. Here we report on a 53-year-old male patient who presented with a rare, delayed-onset motor aphasia caused by a left thalamic hemorrhage.
Source: Journal of the Neurological Sciences - February 23, 2021 Category: Neurology Authors: Tomoyo Shimada, Wataru Uchida, Atsuhiko Shindo, Koji Kamagata, Nobutaka Hattori, Taiji Tsunemi Tags: Letter to the Editor Source Type: research

Predictors and outcomes of hemorrhagic stroke in reversible cerebral vasoconstriction syndrome
In this study, we compared hemorrhagic and non-hemorrhagic RCVS with an aim to evaluate the risk factors and short-term clinical outcomes of hemorrhagic lesions.
Source: Journal of the Neurological Sciences - January 7, 2021 Category: Neurology Authors: Aayushi Garg, Marcelo Rocha, Matthew Starr, Santiago Ortega-Gutierrez Source Type: research

Laboratory factors associated with symptomatic hemorrhagic conversion of acute stroke after systemic thrombolysis
This study aimed to investigate the laboratory factors predisposing to HC in AIS patients receiving IVT.
Source: Journal of the Neurological Sciences - December 9, 2020 Category: Neurology Authors: Haris Kamal, Bijal K. Mehta, M. Khaleeq Ahmed, Katelyn S. Kavak, Alicia Zha, Navdeep S. Lail, Peyman Shirani, Fawaz Al-Mufti, Robert N. Sawyer, Ashkan Mowla Source Type: research

Strategies to prevent hemorrhagic transformation after reperfusion therapies for acute ischemic stroke: A literature review
Reperfusion therapies by tissue plasminogen activator (tPA) and mechanical thrombectomy (MT) have ushered in a new era in the treatment of acute ischemic stroke (AIS). However, reperfusion therapy-related HT remains an enigma.
Source: Journal of the Neurological Sciences - November 3, 2020 Category: Neurology Authors: Yutaka Otsu, Masaki Namekawa, Masafumi Toriyabe, Itaru Ninomiya, Masahiro Hatakeyama, Masahiro Uemura, Osamu Onodera, Takayoshi Shimohata, Masato Kanazawa Tags: Review Article Source Type: research

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