Association of hyperglycemia and computed tomographic perfusion deficits in patients who underwent endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion: A subgroup analysis of a randomized phase 3 trial (MR CLEAN)

Hyperglycemia is highly prevalent in patients with acute ischemic stroke and is associated with increased risk of symptomatic intracranial hemorrhage, larger infarct size and unfavorable outcome. Furthermore, glucose may modify the effect of endovascular treatment (EVT) in patients with ischemic stroke. Hyperglycemia might lead to accelerated conversion of penumbra into infarct core. However, it remains uncertain whether hyperglycemia on admission is associated with the size of penumbra or infarct core in acute ischemic stroke.

Source: Journal of the Neurological Sciences - June 30, 2022 Category: Neurology Authors: C.J.B.A. Kersten, A.A.M. Zandbergen, O.A. Berkhemer, J. Borst, M. Haalboom, Y.B.W.E.M. Roos, D.W.J. Dippel, R.J. van Oostenbrugge, A. van der Lugt, W.H. van Zwam, C.B. Majoie, H.M. den Hertog, on behalf of the MR CLEAN investigators Source Type: research