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Source: Journal of Stroke and Cerebrovascular Diseases

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Factors Associated with the Administration of Tissue Plasminogen Activator for Acute Ischemic Stroke
Conclusions: Our findings suggest that ambulance utilization is an important factor for improving the likelihood of t-PA administration in patients with stroke and may underline a need for educational programs to the general public that promote the use of ambulances for suspected stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2013 Category: Neurology Authors: Susumu Kunisawa, Daisuke Kobayashi, Jason Lee, Tetsuya Otsubo, Hiroshi Ikai, Chiaki Yokota, Kazuo Minematsu, Yuichi Imanaka Tags: Original Articles Source Type: research

Discrimination of Acute Ischemic Stroke from Nonischemic Vertigo in Patients Presenting with Only Imbalance
We examined 332 consecutive patients with an acute feeling of imbalance who showed no neurologic findings or responsible lesions on CT scan at the hyperacute phase. We examined their clinical backgrounds, physical findings, and laboratory examinations, with ischemic stroke diagnosed by later CT and/or magnetic resonance imaging (MRI). We identified 41 (12.3%) ischemic stroke patients. Atrial fibrillation (odds ratio 4.1; 95% confidence interval 1.4-11.5), white blood cell count (103/μL, 1.4; 1.2-1.6), head and/or neck pain (4.6; 2.1-10.3), first attack of imbalance feeling (3.3; 1.1-12.2), and dizziness (3.7; 1.7-8.3) wer...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Shoji Honda, Yuichiro Inatomi, Toshiro Yonehara, Yoichiro Hashimoto, Teruyuki Hirano, Yukio Ando, Makoto Uchino Tags: Original Articles Source Type: research

Evaluating Clinical Effectiveness of Pneumococcal Vaccination in Preventing Stroke: The CAPAMIS Study, 3-Year Follow-up
This study assessed clinical effectiveness of PPV23 in preventing ischemic stroke in people older than 60 years.Methods: We conducted a population-based cohort study involving 27,204 individuals of 60 years or older in Tarragona, Spain, who were prospectively followed from December 01, 2008, until November 30, 2011. Outcomes were neuroimaging-confirmed ischemic stroke, 30-day mortality from stroke, and all-cause death. Pneumococcal vaccination effectiveness was evaluated by Cox regression analyses, estimating hazard ratios (HRs) adjusted for age, sex, comorbidities, and influenza vaccine status.Results: Cohort members were...
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2014 Category: Neurology Authors: Angel Vila-Corcoles, Olga Ochoa-Gondar, Teresa Rodriguez-Blanco, Cinta de Diego-Cabanes, Eva Satue-Gracia, Angel Vila-Rovira, Cristina Torrente Fraga, EPIVAC Research Group Tags: Original Articles Source Type: research

Analysis of the Interleukin-1 Receptor Antagonist Gene Variable Number Tandem Repeats in Ischemic Stroke
Conclusion: Our results do not confirm an association between the gene and ischemic stroke in Caucasian patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2014 Category: Neurology Authors: Leema Reddy Peddareddygari, Souvik Sen, Ankit Pahwa, Mark A. Levenstien, Raji P. Grewal Tags: Original Articles Source Type: research

Stroke Education Using an Animated Cartoon and a Manga for Junior High School Students
Conclusions: Stroke education using these teaching aids of the animated cartoon and the Manga improved stroke knowledge in junior high school students.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2014 Category: Neurology Authors: Yuya Shigehatake, Chiaki Yokota, Tatsuo Amano, Yasuhiro Tomii, Yasuteru Inoue, Takaaki Hagihara, Kazunori Toyoda, Kazuo Minematsu Tags: Original Articles Source Type: research

Quality of Life after Intra-arterial Therapy for Acute Ischemic Stroke
Few data exist about health-related quality of life outcomes after intra-arterial therapy (IAT) for acute ischemic stroke (AIS). We assessed stroke-specific quality of life (SS-QOL) in survivors of stroke after IAT. Consecutive patients undergoing IAT for AIS from 2005 to 2010 were retrospectively identified via an institutional database. SS-QOL (using the SS-QOL score) and disability status (modified Rankin Scale [mRS]) were prospectively assessed via mailed questionnaire. We analyzed quality of life (QOL) scores by domain and summary score, with a summary score of 4 or more defined as a good outcome. Analysis of variance...
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2014 Category: Neurology Authors: Melissa M. Cortez, Michael J. Wilder, Molly McFadden, Jennifer J. Majersik Tags: Original Articles Source Type: research

Effect of Blood Pressure Variability on Cardiovascular Outcome in Diabetic and Nondiabetic Patients with Stroke
Conclusions: We show that SBP variability is associated with cardiovascular outcomes in stroke patients without diabetes, but we didn’t find a correlation between SBP variability and cardiovascular outcomes in stroke patients with diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Bu-Xing Chen, Jun-Ping Tian, Hong-Xia Wang, Jie Xu, Feng-He Du, Xing-Quan Zhao Tags: Original Articles Source Type: research

Stroke Severity and Comorbidity Index for Prediction of Mortality after Ischemic Stroke from the Virtual International Stroke Trials Archive–Acute Collaboration
There is increasing interest in the use of administrative data (incorporating comorbidity index) and stroke severity score to predict ischemic stroke mortality. The aim of this study was to determine the optimal timing for the collection of stroke severity data and the minimum clinical dataset to be included in models of stroke mortality. To address these issues, we chose the Virtual International Stroke Trials Archive (VISTA), which contains National Institutes of Health Stroke Scale (NIHSS) on admission and at 24 hours, as well as outcome at 90 days.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2016 Category: Neurology Authors: Thanh G. Phan, Benjamin Clissold, John Ly, Henry Ma, Chris Moran, Velandai Srikanth, VISTA–Acute Collaboration Source Type: research

Trends in cognitive function assessed by a battery of neuropsychological tests after mild acute ischemic stroke
Cognitive impairment is common after stroke. Most acute ischemic stroke (AIS) patients show cognitive decline in neuropsychological assessments in the early phase of stroke.1,2 Post-stroke cognitive impairment (PSCI) is a broad concept that has been used to define cognitive decline, fulfilling established criteria for cognitive impairment within the first six months following a stroke, which includes post-stroke dementia (PSD) and post-stroke cognitive impairment no dementia (PSCIND).3 Previous studies demonstrated that up to 90% of patients with ischemic stroke had cognitive dysfunction on detailed tests in the acute periods.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2020 Category: Neurology Authors: Yi-Ming Yang, Zhong-Min Zhao, Wei Wang, Fang-Ming Dong, Pan-Pan Wang, Yang-Juan Jia, Ning Han, Yan-Li Jia, Jian-Hua Wang Source Type: research

Pre-Stroke Frailty and Stroke Severity in Elderly Patients with Acute Stroke
Frailty is a major problem in super-aged societies. Because frailty assessments are largely unstudied in acute stroke settings, few reports have evaluated the association between pre-stroke frailty and stroke severity. The aim of this study was to determine the association between pre-stroke frailty and stroke severity in elderly patients with acute stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 5, 2020 Category: Neurology Authors: Masashi Kanai, Madoka Noguchi, Hiroki Kubo, Masafumi Nozoe, Tamami Kitano, Kazuhiro P. Izawa, Kyoshi Mase, Shinichi Shimada Source Type: research

Improvement of Door-to-Imaging Time in Acute Stroke Patients by Implementation of an All-Points Alarm
In patients with acute ischemic stroke, thrombolysis offers an opportunity to effectively reduce disability and dependency. The success of this treatment is time-dependent. The crucial diagnostic step before initiation of treatment is cerebral imaging. With the aim of reducing in-hospital delays, our hospital’s interdisciplinary stroke management group implemented an all-points alarm to improve in-hospital time delay (the period between arrival to the emergency department and performance of cerebral imaging). The alarm simultaneously alerted all involved staff (from the neurologist to in-hospital transport) to the arriva...
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2011 Category: Neurology Authors: Christian H. Nolte, Uwe Malzahn, York Kühnle, Christoph J. Ploner, Jacqueline Müller-Nordhorn, Martin Möckel Tags: Original Articles Source Type: research

Determinants of Emergency Medical Services Use in a Brazilian Population with Acute Ischemic Stroke
This study evaluates the determinants of EMS use in a Brazilian population with acute ischemic stroke. We performed a post hoc analysis of prospectively collected data of consecutive patients admitted to a Brazilian tertiary hospital with acute ischemic stroke. Groups were compared according to their mode of arrival to the hospital: those brought by EMS and those arriving at the hospital by their own means. Among 165 patients evaluated between January and December 2009, 17.6% arrived by EMS and 82.4% arrived by their own means. After multivariate adjustment, individuals with higher National Institutes of Health Stroke Scal...
Source: Journal of Stroke and Cerebrovascular Diseases - October 3, 2011 Category: Neurology Authors: Gustavo W. Kuster, Monique Bueno Alves, Miguel Cendoroglo Neto, Gisele Sampaio Silva Tags: Original Articles Source Type: research

Validation of Minor Stroke Definitions for Thrombolysis Decision Making
Conclusion: Implementation of an optimal definition of minor stroke into thrombolysis decision-making process would decrease the unfavorable outcomes in patients with low NIHSS scores.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Tai Hwan Park, Keun-Sik Hong, Jay Chol Choi, Pamela Song, Ji Sung Lee, Juneyoung Lee, Jong-Moo Park, Kyusik Kang, Kyung Bok Lee, Yong-Jin Cho, Gustavo Saposnik, Moon-Ku Han, Hee-Joon Bae Tags: Original Articles Source Type: research

Bleeding Complications Associated with Warfarin Treatment in Ischemic Stroke Patients with Atrial Fibrillation: A Population-Based Cohort Study
Background: Bleeding events are the major obstacle to the widespread use of warfarin for secondary stroke prevention. Previous studies have not examined the use of risk stratification scores to estimate lifetime bleeding risk associated with warfarin treatment in a population-based setting. The purpose of this study is to determine the lifetime risk of bleeding events in ischemic stroke patients with atrial fibrillation (AF) undergoing warfarin treatment in a population-based cohort and to evaluate the use of bleeding risk scores to identify patients at high risk for lifetime bleeding events.Methods: The resources of the R...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Raymond C.S. Seet, Alejandro A. Rabinstein, Teresa J.H. Christianson, George W. Petty, Robert D. Brown Tags: Original Articles Source Type: research

Gender Difference in Stroke Case Fatality: An Integrated Study of Hospitalization and Mortality
Conclusions: Among persons hospitalized with a stroke in Nebraska between 2005 and 2009, the crude case fatality rate was 50% higher in women. However, after accounting for age and other variables, adjusted mortality rates were essentially the same for men and women.
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2011 Category: Neurology Authors: David DeVries, Ying Zhang, Ming Qu, Jihyun Ma, Ge Lin Tags: Original Articles Source Type: research