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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 6824 results found since Jan 2013.
The Utility of Middle Cerebral Artery Clot Density and Burden Assessment by Noncontrast Computed Tomography in Acute Ischemic Stroke Patients Treated with Thrombolysis
Conclusions: Utility of the HMCAS as a prognostic marker in stroke thrombolysis is not high in the CT angiography era. Previous observation regarding its positive prognostic role can be attributed to its association with proximal location and extent of clot burden, which are detectable reliably with current CT angiography techniques. Neither quantification nor extent of increased density seems to have clinical utility for treatment decision making in MCA strokes and prediction of emboli composition and response to recanalization attempt.
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2013 Category: Neurology Authors: Mehmet A. Topcuoglu, E. Murat Arsava, Oguzhan Kursun, Erhan Akpinar, Bulent Erbil Tags: Original Articles Source Type: research
Self-reported Sleep Duration in Relation to Incident Stroke Symptoms: Nuances by Body Mass and Race from the REGARDS Study
Background: To determine, among employed persons with low risk for obstructive sleep apnea (OSA), if sleep duration is associated with incident stroke symptoms, independent of body mass index (BMI), and if sleep duration mediates racial differences in stroke symptoms.Methods: In 2008, 5666 employed participants (US blacks and whites, ≥45 years) from the longitudinal and nationally representative Reasons for Geographic And Racial Differences in Stroke study self-reported their average sleep duration. Participants had no history of stroke, transient ischemic attack, or stroke symptoms and were at low risk for OSA. After ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Megan E. Ruiter Petrov, Abraham J. Letter, Virginia J. Howard, Dawn Kleindorfer Tags: Original Articles Source Type: research
Investigation of Vaspin Level in Patients with Acute Ischemic Stroke
This study was intended to investigate the relation between vaspin and stroke and stroke and other risk factors.Methods: A total of 50 patients with stroke, as 28 men (56%) and 22 women (44%), and a total of 50 healthy individuals, as 25 men (50%) and 25 women (50%), were enrolled in the study. Blood samples were taken in the acute period (first 48 hours) in the patient group, and serum vaspin levels were measured. Vaspin level was also measured in the control group. The association of vaspin with the lipid parameters, gender, and the severity of internal carotid artery (ICA) stenosis in the patient group was evaluated. S...
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2013 Category: Neurology Authors: Hasan S. Cura, Hasan H. Özdemir, Caner F. Demir, Serpil Bulut, Nevin İlhan, Mehmet Fatih Inci Tags: Original Articles Source Type: research
Early Mobilization after Acute Stroke
Conclusions: Neither time to mobilization nor any other candidate variable was associated with good outcome 3 months poststroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: Antje Sundseth, Bente Thommessen, Ole Morten Rønning Tags: Original Articles Source Type: research
Pooled Assessment of Computed Tomography Interpretation by Vascular Neurologists in the STRokE DOC Telestroke Network
Conclusions: Both vascular neurologists and reports from spoke radiologists had excellent reliability in identifying radiologic rt-PA contraindications. These pooled findings demonstrate that telestroke evaluation of head CT scans for acute rt-PA assessments is reliable.
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2013 Category: Neurology Authors: Ilana Spokoyny, Rema Raman, Karin Ernstrom, Bart M. Demaerschalk, Patrick D. Lyden, Thomas M. Hemmen, Amy K. Guzik, James Y. Chen, Brett C. Meyer Tags: Original Articles Source Type: research
The Impact of World and European Football Cups on Stroke in the Population of Dijon, France: A Longitudinal Study from 1986 to 2006
Conclusions: Watching European football competitions had a positive impact in the city of Dijon with a decrease of stroke numbers. European championship is possibly associated with higher television audience and long-lasting euphoria although other factors may be involved. Further studies using nationwide data are recommended to validate these findings.
Source: Journal of Stroke and Cerebrovascular Diseases - December 9, 2013 Category: Neurology Authors: Corine Aboa-Eboulé, Yannick Béjot, Jonathan Cottenet, Mehni Khellaf, Agnès Jacquin, Jérôme Durier, Olivier Rouaud, Marie Hervieu-Begue, Guy-Victor Osseby, Maurice Giroud, Catherine Quantin Tags: Original Articles Source Type: research
Safety of Protocol Violations in Acute Stroke tPA Administration
Conclusions: Despite more than one third of patients receiving thrombolysis with protocol violations, overall rates of hemorrhage remained low and did not differ from those who did not have violations. Our data support the need to expand access to thrombolysis in AIS patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Michael J. Lyerly, Karen C. Albright, Amelia K. Boehme, Reza Bavarsad Shahripour, James T. Houston, Pawan V. Rawal, Niren Kapoor, Muhammad Alvi, April Sisson, Anne W. Alexandrov, Andrei V. Alexandrov Tags: Original Articles Source Type: research
A Blood-based Biomarker Panel to Detect Acute Stroke
Background: The aim of this study was to develop an adjunctive, peripheral biomarker test to differentiate ischemic strokes, intracranial hemorrhages (ICHs), and stroke mimics in the acute setting.Methods: Serum samples were collected from 167 patients who presented with an acute neurologic deficit within 24 hours of symptom onset. Patients were adjudicated to ischemic stroke, ICH, and mimic pathology groups based on clinical and radiographic findings. Samples were tested for levels of 262 potential markers. A multivariate Cox proportional hazards regression model of 5 biomarkers was built by stepwise selection and valida...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Richa Sharma, Stephanie Macy, Kara Richardson, Yuliya Lokhnygina, Daniel T. Laskowitz Tags: Original Articles Source Type: research
Brain Natriuretic Peptide in Acute Ischemic Stroke
Elevated serum brain natriuretic peptide (BNP) levels are associated with cardioembolic stroke mainly because of atrial fibrillation (AF). However, the mechanisms of increased serum BNP levels are hitherto unclear. We aimed to identify the factors associated with increased BNP levels in patients with acute ischemic stroke. We measured serum BNP levels in consecutive patients aged 18 years or older. Stroke subtypes were classified using the Trial of ORG 10172 in Acute Stroke Treatment criteria. Categorical variables included age, sex, smoking status, alcohol consumption status, hypertension, diabetes mellitus, dyslipidemia...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Kenji Maruyama, Tsuyoshi Shiga, Mutsumi Iijima, Saori Moriya, Satoko Mizuno, Sono Toi, Kotaro Arai, Kyomi Ashihara, Kayoko Abe, Shinichiro Uchiyama Tags: Original Articles Source Type: research
Does Symptom Onset to Primary Stroke Center Time Goals Affect Stroke Outcome?
Background: Treating acute ischemic stroke (AIS) within 4.5 hours and door-to-needle time of less than 60 minutes may optimize recovery. It is unknown if onset to Primary Stroke Center (PSC) time goals affect outcome. The purpose of this study was to examine effects of symptom onset to PSC time goals on outcome.Methods: Analysis included prospectively collected data from the University of California San Diego Specialized Program of Treatment Research in Acute Stroke. All AIS patients treated with intravenous recombinant tissue plasminogen activator were included if treated within 270 minutes, and 90-day modified Rankin ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Bryant Chee, Rema Raman, Karin Ernstrom, Amy K. Guzik, Thomas M. Hemmen, Karen S. Rapp, Brett C. Meyer, Dawn M. Meyer Tags: Original Articles Source Type: research
The Impact of Comprehensive Stroke Care Capacity on the Hospital Volume of Stroke Interventions: A Nationwide Study in Japan: J-ASPECT Study
We examined the effect of hospital characteristics, having a t-PA protocol, and the number of fulfilled CSC items (total CSC score) on the hospital volume of t-PA infusion, removal of intracerebral hemorrhage, and coiling and clipping of intracranial aneurysms performed in 2009.Results: Approximately 55% of hospitals responded to the survey. Facilities with t-PA protocols (85%) had a significantly higher likelihood of having 23 CSC items, for example, personnel (eg, neurosurgeons: 97.3% versus 66.1% and neurologists: 51.3% versus 27.7%), diagnostic (eg, digital cerebral angiography: 87.4% versus 43.2%), specific expertise...
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Koji Iihara, Kunihiro Nishimura, Akiko Kada, Jyoji Nakagawara, Kazunori Toyoda, Kuniaki Ogasawara, Junichi Ono, Yoshiaki Shiokawa, Toru Aruga, Shigeru Miyachi, Izumi Nagata, Shinya Matsuda, Koichi B. Ishikawa, Akifumi Suzuki, Hisae Mori, Fumiaki Nakamura, Tags: Original Articles Source Type: research
Quality of Life after Lacunar Stroke: The Secondary Prevention of Small Subcortical Strokes Study
Background: We sought to describe the course and predictors of quality of life (QOL) after lacunar stroke. We hypothesized that there is a decline in QOL after recovery from lacunar stroke.Methods: The Secondary Prevention of Small Subcortical Strokes is a clinical trial in lacunar stroke patients with annual assessments of QOL with the stroke-specific QOL score. The overall score was used and analyzed as a continuous variable (range 0-5). We fit linear mixed models to assess the trend in QOL over time, assuming linearity of time, and adjusted for demographics, medical risk factors, cognitive factors, and functional status...
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2013 Category: Neurology Authors: Mandip S. Dhamoon, Leslie A. McClure, Carole L. White, Helena Lau, Oscar Benavente, Mitchell S.V. Elkind Tags: Original Articles Source Type: research
Synthetic Cannabis and Acute Ischemic Stroke
We describe 2 cases that introduce a previously unreported association between synthetic cannabis use and ischemic stroke in young adults. A 22-year-old woman presented with dysarthria, left hemiplegia, and left hemianesthesia within hours of first use of synthetic cannabis. She was healthy and without identified stroke risk factors other than oral contraceptive use and a patent foramen ovale without venous thromboses. A 26-year-old woman presented with nonfluent aphasia, left facial droop, and left hemianesthesia approximately 12 hours after first use of synthetic cannabis. Her other stroke risk factors included migraine ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Miya E. Bernson-Leung, Lester Y. Leung, Sandeep Kumar Tags: Case Reports Source Type: research
Nontraumatic Convexal Subarachnoid Hemorrhage Concomitant with Acute Ischemic Stroke
Conclusions: In this retrospective review of cases with ischemic stroke and cSAH, over half of patients had occlusion of major arteries. Cerebral amyloid angiopathy was suggested by magnetic resonance imaging findings and subsequent events in 3 patients. The overall outcome was unfavorable although the causal relationship with cSAH was unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - March 17, 2014 Category: Neurology Authors: Makoto Nakajima, Yuichiro Inatomi, Toshiro Yonehara, Teruyuki Hirano, Yukio Ando Tags: Original Articles Source Type: research
Outcomes in People after Stroke Attending an Adapted Cardiac Rehabilitation Exercise Program: Does Time from Stroke Make a Difference?
The objectives of the present study are (1) to evaluate the effects of a CRP in participants with motor impairment after stroke and (2) to explore the effects of elapsed time from stroke on physiological/quality-of-life outcomes.Methods: The CRP included 24 weeks of resistance and aerobic training. Primary outcomes in 120 participants, 25.4 ± 42.3 (mean ± standard deviation) months after stroke, included 6-minute walk distance (6MWD), VO2peak, timed repeated sit-to-stand performance, and affected-side isometric knee extensor strength (IKES). Secondary measures included gait characteristics (cadence, step lengths, an...
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2014 Category: Neurology Authors: Susan Marzolini, Ada Tang, William McIlroy, Paul I. Oh, Dina Brooks Tags: Original Articles Source Type: research
