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Source: Journal of Stroke and Cerebrovascular Diseases

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Total 6824 results found since Jan 2013.

The Frequency of Poststroke Infections and Their Impact on Early Stroke Outcome
Introduction: Poststroke infections are the most common medical complications of stroke and can occur in up to 65% of patients. The aim of this study was to assess the rate of infectious complications during hospitalization of stroke patients and to evaluate the impact of infection in general, including each of the urinary tract infection (UTI), pneumonia, and sepsis, on fatal and poor functional outcome at discharge.Methods: This retrospective study enrolled patients who have been diagnosed with acute ischemic stroke treated in a 1-year period. Poor functional outcome at discharge was defined as severe invalidity and incl...
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2013 Category: Neurology Authors: Natasa Popović, Maja Stefanović-Budimkić, Nikola Mitrović, Aleksandar Urošević, Branko Milošević, Mijomir Pelemiš, Djordje Jevtović, Ljiljana Beslać-Bumbaširević, Dejana Jovanović Tags: Original Articles Source Type: research

Prediction of Thrombolytic Therapy after Stroke-Bypass Transportation: The Maria Prehospital Stroke Scale Score
There is no prehospital stratification tool specifically for predicting thrombolytic therapy after transportation. We developed a new prehospital scale named the Maria Prehospital Stroke Scale (MPSS) by modifying the Cincinnati Prehospital Stroke Scale. Our objective is to evaluate its utility in a citywide bypass transportation protocol for intravenous (IV) tissue plasminogen activator (tPA). In the MPSS, facial droop, arm drift, and speech disturbance are tested by emergency medical technicians (EMTs). Facial droop is graded as normal (0) or abnormal (1), and the other 2 items are graded in 3 levels as normal (0), not se...
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2013 Category: Neurology Authors: Yasuhiro Hasegawa, Naoshi Sasaki, Koji Yamada, Hajime Ono, Junichiro Kumai, Kotaro Tsumura, Kazunari Suzuki, Hiroyuki Nozaki, Hitoshi Nakayama, Ichiro Takumi, Hirofumi Nikaido, Tuyoshi Katabami, Toshihiro Ueda, Shinichi Suzuki, Ryosei Iwai, Hiroshi Takaha Tags: Original Articles Source Type: research

Screening for NOTCH3 Gene Mutations Among 151 Consecutive Korean Patients with Acute Ischemic Stroke
Conclusions: In this region, NOTCH3 gene mutations are frequently found in acute stroke patients who present with neuroimaging features consistent with advanced small-vessel disease.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2011 Category: Neurology Authors: Jay Chol Choi, Keun-Hwa Lee, Sook-Keun Song, Jung Seok Lee, Sa-Yoon Kang, Ji-Hoon Kang Tags: Original Articles Source Type: research

Low-Normal Systolic Blood Pressure and Secondary Stroke Risk
A recent observational study of>20,000 patients with recent ischemic stroke suggested that systolic blood pressure (SBP) maintained in a low-normal range may be associated with increased risk of recurrent stroke, especially within the first 6 months after the first stroke. Using a distinct cohort, the current study aimed to independently evaluate the relationship between low-normal SBP levels and risk of recurrent stroke through analysis of a trial dataset involving 3680 patients with recent noncardioembolic ischemic stroke aged ≥35 years recruited from 56 centers between September 1996 and May 2003 and followed for 2 ye...
Source: Journal of Stroke and Cerebrovascular Diseases - January 16, 2012 Category: Neurology Authors: Bruce Ovbiagele Tags: Original Articles Source Type: research

Safety of Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Saccular Intracranial Aneurysms
Conclusions: Intravenous thrombolysis was safe among our patients with acute ischemic stroke and incidental intracranial saccular aneurysm.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2012 Category: Neurology Authors: Manoj K. Mittal, Raymond C.S. Seet, Yi Zhang, Robert D. Brown, Alejandro A. Rabinstein Tags: Original Articles Source Type: research

What Change in the National Institutes of Health Stroke Scale Should Define Neurologic Deterioration in Acute Ischemic Stroke?
Background: Neurologic deterioration (ND) occurs in one-third of patients with stroke. However, the true incidence of ND and risk for adverse outcomes remains unknown because no standardized definition of ND exists. Our study compared the prognostic value of a range of definitions for ND in patients with acute ischemic stroke (AIS).Methods: All patients who presented to our center with AIS within 48 hours of symptom onset between July 2008 and June 2010 were retrospectively identified. Patient demographics, National Institutes of Health Stroke Scale (NIHSS) scores, etiologies of ND, and outcome measures were compared betw...
Source: Journal of Stroke and Cerebrovascular Diseases - June 25, 2012 Category: Neurology Authors: James E. Siegler, Amelia K. Boehme, Andre D. Kumar, Michael A. Gillette, Karen C. Albright, Sheryl Martin-Schild Tags: Original Articles Source Type: research

Antithrombotic Management of Stroke Patients Before Colonoscopy
Conclusions: In this retrospective analysis, there was no significant difference in the occurrence of stroke, myocardial infarction, venous thromboembolism, and major bleeding between patients who had medications continued around the time of colonoscopy versus those who had temporary discontinuation. A prospective, randomized controlled study is warranted to further elucidate this issue.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2012 Category: Neurology Authors: Basel Assaad, Veronica Kemerko Sesi, Renzo Figari, Lonni Schultz, Nithin Thummala, Mohammed Rehman, Arun Chandok, Ann Silverman, Brian Silver Tags: Original Articles Source Type: research

Epidemiology, Pathophysiology, and Treatment of Hypertension in Ischaemic Stroke Patients
Stroke continues to be one of the leading causes of mortality and morbidity worldwide. There are 2 main types of stroke: ischaemic strokes, which are caused by obstruction of the blood vessels leading to or within the brain, and haemorrhagic strokes, which are induced by the disruption of blood vessels. Stroke is a disease of multifactorial aetiology that may develop as an end state in patients with serious vascular conditions—most notably, uncontrolled arterial hypertension—thereby necessitating the effective control of this risk factor to prevent stroke or its recurrence. This paper focuses specifically on the epidem...
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2012 Category: Neurology Authors: Nur Fatirul Hisham, Ulvi Bayraktutan Tags: Review Articles Source Type: research

Population Trends and Disparities in Outpatient Utilization of Neurologists for Ischemic Stroke
Conclusions: Between 1998 and 2009, IS-related outpatient utilization increased substantially to neurologists but declined to generalists. We identified demographic variations in outpatient utilization of neurologists that potentially lead to disparities in stroke evaluation and management.
Source: Journal of Stroke and Cerebrovascular Diseases - December 26, 2011 Category: Neurology Authors: Sudeep Karve, Rajesh Balkrishnan, Eric Seiber, Milap Nahata, Deborah A. Levine Tags: Original Articles Source Type: research

Exclusion Criteria for Intravenous Thrombolysis in Stroke Mimics: An Observational Study
Conclusions: SM patients frequently had exclusion criteria for systemic thrombolysis, the most frequent being presenting beyond the established thrombolytic window.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Alejandro M. Brunser, Sergio Illanes, Pablo M. Lavados, Paula Muñoz, Daniel Cárcamo, Arnold Hoppe, Verónica V. Olavarria, Iris Delgado, Violeta Díaz Tags: Original Articles Source Type: research

Short-term Bleeding Events Observed with Clopidogrel Loading in Acute Ischemic Stroke Patients
Discussion: Contrary to our original hypothesis, patients with AIS receiving clopidogrel loading doses within 24 hours of symptom onset did not appear to experience a higher rate of new serious bleeding events during acute hospitalization when compared with patients who did not receive loading doses. The Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke trial is expected to provide insight into the safety of clopidogrel loading as an acute intervention after cerebral ischemia.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Lester Y. Leung, Karen C. Albright, Amelia K. Boehme, Joseph Tarsia, Kamal R. Shah, James E. Siegler, Erica M. Jones, Gayle R. Pletsch, Timothy M. Beasley, Sheryl Martin-Schild Tags: Original Articles Source Type: research

Zoster Sine Herpete, Vertebral Artery Stenosis, and Ischemic Stroke
We report an immunocompetent man with common cold symptoms and conjunctivitis, followed by an acute onset of bulbar weakness and hemihypesthesia without preceding skin rash. Acute medullary infarction and left vertebral artery stenosis were detected. VZV infection was finally identified. Zoster sine herpetic interferes with accurate diagnosis of infectious stroke, and vertebral artery involvement is unusual in ischemic stroke in this situation. An unexplained course of ischemic stroke event should be suspected in patients with VZV cerebrovasculopathy, especially in those without conventional stroke risk factors and those...
Source: Journal of Stroke and Cerebrovascular Diseases - September 12, 2012 Category: Neurology Authors: Wei-Hsi Chen, Chi Chui, Hsin-Ling Yin Tags: Case Reports Source Type: research

Sleep Apnea Treatment After Stroke (SATS) Trial: Is It Feasible?
Sleep apnea affects more than half of patients with acute ischemic stroke and is associated with poor stroke outcome. This pilot study assessed the feasibility of a randomized, sham-controlled continuous positive airway pressure (CPAP) trial in subjects with acute ischemic stroke. Subjects identified with sleep apnea based on an apnea-hypopnea index ≥5 on overnight polysomnography or portable respiratory monitoring within 7 days of onset of stroke symptoms were randomized to receive active or sham CPAP for a 3-month period. Objective usage was ascertained by compliance data cards. Subjects, treating physicians, and outco...
Source: Journal of Stroke and Cerebrovascular Diseases - July 25, 2011 Category: Neurology Authors: Devin L. Brown, Ronald D. Chervin, John D. Kalbfleisch, Michael J. Zupancic, Erin M. Migda, Anna Svatikova, Maryann Concannon, Cory Martin, Kevin J. Weatherwax, Lewis B. Morgenstern Tags: Original Articles Source Type: research

Treatment of Acute Stroke in Patients on Dabigatran: A Survey of US Stroke Specialists
Conclusions: There is a remarkable lack of consensus among vascular neurologists regarding the assessment and treatment of acute stroke patients on dabigatran.
Source: Journal of Stroke and Cerebrovascular Diseases - January 14, 2013 Category: Neurology Authors: Igor Rybinnik, Michael T. Mullen, Steven Messe, Scott E. Kasner, Brett Cucchiara Tags: Original Articles Source Type: research