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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 6824 results found since Jan 2013.
Impact of the COVID-19 pandemic on stroke epidemiology and clinical stroke practice in the US
: To examine the impact of the COVID-19 pandemic on stroke, the number of stroke patients, time since last known well (LKW), morbidity, and mortality of stroke patients in Southwest Healthcare System (SHS), California (CA) and the United States (US) were analyzed during 2019 and compared to 2020. Our hypothesis is that there are regional differences in stroke outcome depending on location during the COVID-19 study period which influences stroke epidemiology and clinical stroke practice.
Source: Journal of Stroke and Cerebrovascular Diseases - January 26, 2021 Category: Neurology Authors: Daniel Friedlich, Tali Newman, Stephanie Bricker Source Type: research
Clinical Outcomes and Costs of Recurrent Ischemic Stroke: A Systematic Review
Stroke is one of the leading causes of morbidity and mortality worldwide1 associated with significant healthcare costs.2 The burden of stroke is frequently reported as the incidence of first-event stroke, but the prevalence of total stroke events, including recurrent stroke, more accurately reflects the true burden.3,4 Nearly 30% of all strokes are recurrent events, and the risk is highest in the period immediately following a stroke.5 In particular, patients who have suffered an ischemic stroke are at a higher risk of experiencing one or more subsequent strokes.
Source: Journal of Stroke and Cerebrovascular Diseases - April 6, 2022 Category: Neurology Authors: Sophia R. Ferrone, Artem T. Boltyenkov, Zachary Lodato, Joseph O'Hara, Jaclyn Vialet, Ajay Malhotra, Jeffrey M. Katz, Jason J. Wang, Chinara Feizullayeva, Pina C. Sanelli Source Type: research
Cincinnati Prehospital Stroke Scale Implementation of an Urban County Severity-Based Stroke Triage Protocol: Impact and Outcomes on a Comprehensive Stroke Center
This study addresses the impact of county-based CPSS implementation to triage suspected LVO patients to a comprehensive stroke center (CSC).
Source: Journal of Stroke and Cerebrovascular Diseases - June 2, 2022 Category: Neurology Authors: Ghada A. Mohamed, Fahad Marmarchi, Yombe Fonkeu, Qasem Alshaer, Srikant Rangaraju, Michael Carr, Andrew Jones, Matthew Peczka, Israel Contreras, Lori Bahdsalvi, Cynthia Brasher, Fadi Nahab Source Type: research
Association between physical activity levels and depressive symptoms in patients with minor ischemic stroke
Post-stroke depression (PSD) in stroke patients is a serious sequela. The incidence of depression in stroke patients is approximately 22% –35%.1,2 PSD is associated with serious outcomes, leading to increased risk of mortality and reduced quality of life.3 In addition, a previous study investigating the association between depression and stroke recurrence in ischemic stroke (IS) patients reported that post-IS depression is an indepe ndent risk factor for stroke recurrence.4 Thus, prevention of PSD is important, as this could lead to further adverse functional outcomes after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2022 Category: Neurology Authors: Ryota Ashizawa, Hiroya Honda, Kohei Yoshizawa, Yuto Kameyama, Yoshinobu Yoshimoto Source Type: research
Less is more - The Finnish Prehospital Stroke Scale prospective validation
The current bifurcation of the acute stroke care pathway requires prehospital separation of strokes caused by large vessel occlusion. The first four binary items of the Finnish Prehospital Stroke Scale (FPSS) identify stroke in general, while the fifth binary item alone identifies stroke due to large vessel occlusion. The straightforward design is both easy for paramedics and statistically beneficial. We implemented FPSS based Western Finland Stroke Triage Plan, including medical districts of a comprehensive stroke center and four primary stroke centers.
Source: Journal of Stroke and Cerebrovascular Diseases - February 16, 2023 Category: Neurology Authors: Jyrki Ollikainen, Pasi Jolma, Juha-Pekka Pienim äki, Pauli Vuorinen, Niku Oksala, Marko Kimpimäki, Markku Grönroos, Tuuli-Maria Haula, Heikki Janhunen, Satu-Liisa Pauniaho Source Type: research
Development of the stroke patient concerns inventory: A modified Delphi study
Globally, there are estimated to be almost 25.7 million stroke survivors, and stroke is the third most common cause of disability worldwide.1 The impact of stroke is sudden, and can be devastating and life-changing.2 A stroke can result in a range of short and long-term physical, psychological and social problems for survivors.3 –6 Stroke survivors’ needs can present at different times post-stroke and differ between individuals. Evidence suggests that, long-term, stroke survivors’ needs are often inadequately met.
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2023 Category: Neurology Authors: Brigit M. Chesworth, Kulsum Patel, Judith Redfern, Caroline L. Watkins, Simon N. Rogers, Maree L. Hackett, Marion F. Walker, Catherine E. Lightbody Source Type: research
Red blood cell distribution width to platelet ratio predicts early neurological deterioration in acute ischemic stroke patients receiving intravenous thrombolysis
Stroke is a disease that seriously threatens human health, with high incidence, a high disability rate and high mortality.1 –4 The occurrence rate of stroke ranks second in China, and stroke is a major contributor to disability and the main cause of death in China.1,2,4 Stroke patients suffer from not only neurological dysfunction but also serious social and psychological obstacles, which seriously affect their quality of life and place a massive economic burden on their families and society.1,5,6 Acute ischemic stroke (AIS) is the most common type of stroke, accounting for approximately 70% of the stroke cases in China.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2023 Category: Neurology Authors: Min Jiang, Jun Shen, Bilal Muhammad, Deqin Geng Source Type: research
Post-stroke pneumonia: Factors associated with readmission within 90 days of stroke discharge
Stroke is the fifth leading cause of death and a leading cause of disability within the United States.1,2 On average, a stroke occurs every 40 seconds and accounts for approximately 1 in every 19 deaths.2 The prevalence of stroke is projected to increase by 20.5% from 2012 to 2030.2 Post-stroke complications are prevalent; infection occurs among 30% of acute cases.3 Pneumonia is one of the most common post-stroke infections and is associated with increased morbidity.4,5 Moreover, pneumonia is recognized as an independent risk factor for stroke-related mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - August 21, 2023 Category: Neurology Authors: Tiffany Bouddhara, LeighAnn Persondek, Elizabeth Ablah, Hayrettin Okut, Liuqiang Lu, James Walker Source Type: research
Tissue Plasminogen Activator Thrombolytic Therapy for Acute Ischemic Stroke in 4 Hospital Groups in Japan
In October 2005 in Japan, the recombinant tissue plasminogen activator (tPA) alteplase was approved for patients with acute ischemic stroke within 3 hours of onset at a dose of 0.6 mg/kg. The present study was undertaken to assess the safety and efficacy of alteplase in Japan. Between October 2005 and December 2009, a total of 114 consecutive patients admitted to 4 hospitals received intravenous tPA within 3 hours of stroke onset. Clinical backgrounds and outcomes were investigated. The patients were divided into 2 chronological groups: an early group, comprising 45 patients treated between October 2005 and December 2007,...
Source: Journal of Stroke and Cerebrovascular Diseases - October 4, 2011 Category: Neurology Authors: Syoichiro Kono, Kentaro Deguchi, Nobutoshi Morimoto, Tomoko Kurata, Shoko Deguchi, Tohru Yamashita, Yoshio Ikeda, Tohru Matsuura, Hisashi Narai, Nobuhiko Omori, Yasuhiro Manabe, Taijyun Yunoki, Yoshiki Takao, Sanami Kawata, Kenichi Kashihara, Koji Abe Tags: Original Articles Source Type: research
Demographic, Clinical, and Radiologic Predictors of Neurologic Deterioration in Patients with Acute Ischemic Stroke
One-third of patients with acute ischemic stroke develop early neurologic worsening, which is associated with increased mortality and long-term functional disability. We investigated the predictive factors for neurologic deterioration in patients with acute ischemic stroke within 1 week of onset. We retrospectively investigated 643 patients who were admitted within 2 days of acute ischemic stroke between April 2007 and March 2010. Neurologic deterioration was defined as an increase of 4 points or more in the National Institutes of Health Stroke Scale (NIHSS) score within 1 week of admission. We retrieved data on demograph...
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2011 Category: Neurology Authors: Nobukazu Miyamoto, Yasutaka Tanaka, Yuji Ueno, Miyako Kawamura, Yoshiaki Shimada, Ryota Tanaka, Nobutaka Hattori, Takao Urabe Tags: Original Articles Source Type: research
Survival and Differentiation of Transplanted Neural Stem Cells Derived from Human Induced Pluripotent Stem Cells in A Rat Stroke Model
Conclusions: To our knowledge, this is the first report of transplantation of NSCs derived from human iPSCs in a stroke model. Human iPSC-derived NSCs survived in the postischemic rat brain and appeared to differentiate, primarily into neurons. This cell transplantation approach for stroke appears to be feasible, but further optimization is needed.
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2011 Category: Neurology Authors: Matthew B. Jensen, Hongmei Yan, Rajeev Krishnaney-Davison, Abdullah Al Sawaf, Su-Chun Zhang Tags: Original Articles Source Type: research
Remote Assessment of Stroke Using the iPhone 4
This study demonstrates the efficacy of using the relatively inexpensive iPhone 4 in telestroke management. Twenty patients with stroke were assessed at the bedside using an iPhone 4, and each examination was directed remotely on another iPhone 4. Both the physician performing the bedside exam and the remote physician calculated a National Institutes of Health Stroke Scale (NIHSS) score for each patient. Each physician was blinded to the other’s NIHSS score. In the 20 patients assessed, NIHSS scores ranged from 0 to 22. Interrater reliability assessed using the κ statistic demonstrated excellent agreement in 10 items (l...
Source: Journal of Stroke and Cerebrovascular Diseases - October 24, 2011 Category: Neurology Authors: Eric R. Anderson, Bryan Smith, Moges Ido, Michael Frankel Tags: Original Articles Source Type: research
Comparison of the Effects of High- and Low-frequency Repetitive Transcranial Magnetic Stimulation on Upper Limb Hemiparesis in the Early Phase of Stroke
Background: Recently, high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) and low-frequency rTMS (LF-rTMS) are reported to improve motor function significantly in chronic hemiparetic stroke patients. However, few studies have investigated the safety and efficacy of these rTMS modalities introduced during the early phase of stroke. The purpose of this study was to clarify the rTMS modality that is more beneficial for upper limb hemiparesis in the early phase of stroke using a randomized controlled trial.Methods: Twenty-nine patients with a hemispheric stroke lesion in the early phase of stroke were examine...
Source: Journal of Stroke and Cerebrovascular Diseases - December 16, 2011 Category: Neurology Authors: Nobuyuki Sasaki, Saneyuki Mizutani, Wataru Kakuda, Masahiro Abo Tags: Original Articles Source Type: research
Recent Trends in Inpatient Mortality and Resource Utilization for Patients with Stroke in the United States: 2005-2009
Background: The aim of the study is to evaluate recent trends in mortality, length of stay, costs, and charges for patients admitted to the US hospitals with the principal diagnosis of stroke.Methods: This was a retrospective temporal trends study using data from the Nationwide Inpatient Sample from 2005 to 2009.Results: During the study period, there were 2.7 million hospital admissions with the diagnosis of stroke in the United States (470,000 intracerebral hemorrhage, 130,000 subarachnoid hemorrhage, and 2.1 million ischemic strokes). In-hospital mortality decreased from 10.2% in 2005 to 9.0% in 2009 (26.0%-23.0%, 23.4...
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Maria Stepanova, Chapy Venkatesan, Laith Altaweel, Alita Mishra, Zobair M. Younossi Tags: Original Articles Source Type: research
Impact of Telemedicine Implementation in Thrombolytic Use for Acute Ischemic Stroke: The University of Pittsburgh Medical Center Telestroke Network Experience
Background: Intravenous thrombolysis is the only therapy for acute ischemic stroke that is approved by the US Food and Drug Association. The use of telemedicine in stroke makes it possible to bring the expertise of academic stroke centers to underserved areas, potentially increasing the quality of stroke care.Methods: All consecutive admissions for stroke were reviewed for 1 year before telemedicine implementation and for variable periods thereafter. A retrospective review identified 2588 admissions for acute stroke between March 2005 and December 2008 at 12 hospitals participating in a telestroke network, including 919 pa...
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2013 Category: Neurology Authors: Edilberto Amorim, Min-Mei Shih, Steven A. Koehler, Lori L. Massaro, Syed F. Zaidi, Mouhammad A. Jumaa, Vivek K. Reddy, Maxim D. Hammer, Tudor G. Jovin, Lawrence R. Wechsler Tags: Original Articles Source Type: research
