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Source: Journal of Stroke and Cerebrovascular Diseases

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Total 6824 results found since Jan 2013.

Troponin Elevation Predicts Atrial Fibrillation in Patients with Stroke or Transient Ischemic Attack
Conclusions: cTnI elevation predicts new-onset AF on 24-hour Holter measurement in patients with acute ischemic stroke or TIA and may indicate a poorer prognosis and a higher risk of stroke, MI, and death at 3 months.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2012 Category: Neurology Authors: Isabelle Beaulieu-Boire, Nancy Leblanc, Léo Berger, Jean-Martin Boulanger Tags: Original Articles Source Type: research

The Relationship between Knowledge and Risk for Heart Attack and Stroke
Background: Stroke and myocardial infarction (MI) represent 2 of the leading causes of death in the United States. The early recognition of risk factors and event symptoms allows for the mitigation of disability or death. We sought to compare subject knowledge of stroke and MI, assess subject risk for cardiovascular disease, and determine if an association exists between knowledge and risk.Methods: In this cross-sectional survey, adult, non–health care professionals were presented with a written knowledge test and risk assessment tool. Subjects were classified into 3 categories of cardiovascular risk. Associations were t...
Source: Journal of Stroke and Cerebrovascular Diseases - March 12, 2012 Category: Neurology Authors: Cameron Lambert, Seth Vinson, Frances Shofer, Jane Brice Tags: Original Articles Source Type: research

The Totaled Health Risks in Vascular Events (THRIVE) Score Predicts Ischemic Stroke Outcomes Independent of Thrombolytic Therapy in the NINDS tPA Trial
Conclusions: The THRIVE score provides accurate prediction of long-term neurologic outcomes in patients with acute ischemic stroke regardless of treatment modality. Both the THRIVE score and tPA administration predict outcome, but the THRIVE score does not influence the impact of tPA on outcome, and tPA administration does not influence the impact of THRIVE score on outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - November 5, 2012 Category: Neurology Authors: Hooman Kamel, Nihar Patel, Vivek A. Rao, Sean P. Cullen, Bonnie S. Faigeles, Wade S. Smith, Alexander C. Flint Tags: Original Articles Source Type: research

Intravenous Thrombolysis with Neuroprotective Therapy by Edaravone for Ischemic Stroke Patients Older than 80 Years of Age
Background: Alteplase, a recombinant tissue plasminogen activator (tPA), was approved for patients with acute ischemic stroke within 3 hours of stroke onset in Japan in October 2005 at a dose of 0.6 mg/kg. The aim of this study was to assess the safety and efficacy of alteplase in elderly patients in Japan.Methods: One hundred twenty-nine consecutive patients who were admitted to our 5 hospital groups and who received intravenous tPA within 3 hours of stroke onset between January 2010 and December 2011 were divided into 2 groups by age (80 years of age [older group]) and by treatment with or without edaravone. Clinical bac...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Syoichiro Kono, Kentaro Deguchi, Nobutoshi Morimoto, Tomoko Kurata, Toru Yamashita, Yoshio Ikeda, Hisashi Narai, Yasuhiro Manabe, Yoshiki Takao, Sanami Kawada, Kenichi Kashihara, Yasushi Takehisa, Satoshi Inoue, Hideki Kiriyama, Koji Abe Tags: Original Articles Source Type: research

Improving the Prediction of Stroke or Death After Transient Ischemic Attack (TIA) by Adding Diffusion-weighted Imaging Lesions and TIA Etiology to the ABCD2 Score
The present study investigated the addition of transient ischemic attack (TIA) etiology and diffusion-weighted imaging (DWI) to the ABCD2 score, creating the ABCDE+ score, to improve the predictive ability of stroke risk or death at 6 months after TIA. We performed a cohort study of 150 consecutive patients with TIA. All patients underwent DWI and all had an etiologic workup and were followed up for 6 months. The area under the receiver operating characteristic curve (AUC) was used to compare the scores' ability to predict the outcome of stroke or death. Multivariate Cox regression analysis was performed to evaluate the as...
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2012 Category: Neurology Authors: Ali Arhami Dolatabadi, Amirhosein Meisami, Hamidreza Hatamabadi, Behnam Mansori, Ali Shahrami, Afshin Amini, Kazem Jamali Tags: Original Articles Source Type: research

Brain Natriuretic Peptide: A Relevant Marker to Rule Out Delayed Atrial Fibrillation in Stroke Patient
Detection of new atrial fibrillation (AF) after ischemic stroke is challenging. The aim of the TARGET-AF study was to identify relevant markers for ruling out delayed AF in stroke patients. Early and prolonged Holter electrocardiography (ECG) monitoring during hospitalization was performed systematically in consecutive acute stroke patients naive to AF (no history of AF or no AF on baseline ECG). All clinical and paraclinical data for routine etiologic assessment were collected. The diagnostic value of all parameters significantly associated with AF was assessed by comparison of area under the receiver operating characteri...
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2012 Category: Neurology Authors: Laurent Suissa, Saskia Bresch, Sylvain Lachaud, Marie Hélène Mahagne Tags: Original Articles Source Type: research

White Matter Changes on Magnetic Resonance Imaging: A Risk Factor for Stroke in an African Population?
Background: White matter changes are frequently observed incidental findings in elderly individuals. Many studies in Europe and the United States have assessed the association of white matter changes with stroke and other diseases. No similar study has been conducted in sub-Saharan Africa, where risk factors for stroke differ. Our objective was to explore the association between severity of white matter changes (based on visual rating scales) and stroke in a Nigerian population.Methods: Magnetic resonance imaging (MRI) scans of 50 patients were retrospectively assessed and scored using 3 different visual rating scales (by ...
Source: Journal of Stroke and Cerebrovascular Diseases - February 4, 2013 Category: Neurology Authors: Godwin I. Ogbole, Mayowa O. Owolabi, Bolutife P. Yusuf Tags: Original Articles Source Type: research

Validation of the 12-Item Stroke-Specific Quality of Life Scale in a Biethnic Stroke Population
This study in patients with ischemic stroke from diverse racial/ethnic backgrounds found that the more efficient 12-item SSQOL is a valid alternative to the full 49-item SSQOL for the assessment of health-related quality of life.
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2012 Category: Neurology Authors: Kevin A. Kerber, Devin L. Brown, Lesli E. Skolarus, Lewis B. Morgenstern, Melinda A. Smith, Nelda M. Garcia, Lynda D. Lisabeth Tags: Original Articles Source Type: research

The CHA(2)DS(2)-VASc Score Reflects Clinical Outcomes in Nonvalvular Atrial Fibrillation Patients with an Initial Cardioembolic Stroke
Conclusions: The severity of NVAF-induced initial cardioembolic stroke increased with higher CHA(2)DS(2)-VASc scores, and the outcomes were poor. The present study suggests that the CHA(2)DS(2)-VASc score may be useful not only for the evaluation of stroke risk but also for the prediction of clinical outcomes after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 25, 2013 Category: Neurology Authors: Ichiro Deguchi, Takeshi Hayashi, Yasuko Ohe, Yuji Kato, Harumitsu Nagoya, Takuya Fukuoka, Hajime Maruyama, Yohsuke Horiuchi, Norio Tanahashi Tags: Original Articles Source Type: research

Short- and Long-term Survival after Stroke in Hospitalized Patients in Chile: A Nationwide 5-Year Study
Conclusions: Short- and long-term survival after ischemic stroke was heterogeneous by geographic regions and type of health insurance, regardless age and sex were the strongest predictors. This suggests an impact of socioeconomic factors and access to acute management of strokes on survival.
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2013 Category: Neurology Authors: Lorena Hoffmeister, Pablo M. Lavados, Cristiane Murta-Nascimento, Miguel Araujo, Verónica V. Olavarría, Xavier Castells Tags: Original Articles Source Type: research

Glycosylated Hemoglobin for Diagnosis of Prediabetes in Acute Ischemic Stroke Patients
Background: Prediabetes (PD) is an independent risk factor for stroke. The American Diabetes Association (ADA) has recently published new guidelines recommending glycosylated hemoglobin A1c (HbA1c) as a marker to diagnose diabetes and PD. Diagnosis of diabetes Mellitus (DM) is often made at the time of hospitalization for stroke. Less is known about identifying PD in acute ischemic stroke (AIS) patients. We aim to investigate the frequency of new-onset PD in the hospitalized AIS patients using the new ADA guidelines.Methods: We retrospectively studied 362 AIS patients from our local database. Stroke risk factors, type of s...
Source: Journal of Stroke and Cerebrovascular Diseases - July 19, 2013 Category: Neurology Authors: Branko N. Huisa, Gulmohor Roy, Jorge Kawano, Ronald Schrader Tags: Original Articles Source Type: research

Stroke Subtypes and Comorbidity among Ischemic Stroke Patients in Brasilia and Cuenca: A Brazilian–Spanish Cross-cultural Study
Background: With the increase in life expectancy worldwide, changes in stroke subtypes and burden of stroke population are expected in both developing and developed countries. Prevalence of stroke subtypes and comorbidity in ischemic stroke patients was assessed in Brasilia, Brazil, and Cuenca, Spain.Methods: This was an international (Brazilian-Spanish) cross-sectional study. Stroke subtypes were assessed by means of Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification. Modified Rankin scale was used to measure functional recovery and the Cumulative Illness Rating Scale for Geriatrics (CIRS-G) was used to a...
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Francisco Javier Carod-Artal, Jardiel Omar Casanova Lanchipa, Luis Miguel Cruz Ramírez, Noelia Sánchez Pérez, Fátima M. Siacara Aguayo, Isabel Gómez Moreno, Lourdes Gómez Romero, Luciene Ferreira Coral, Daniele Stieven Trizotto, Clarissa Menezes Mor Tags: Original Articles Source Type: research

Initial Experience with Upfront Arterial and Perfusion Imaging among Ischemic Stroke Patients Presenting within the 4.5-hour Time Window
Conclusions: An upfront CTA/CTP protocol aided stroke team decision-making in nearly half of cases. Implementation of a CTA/CTP protocol was associated with a learning curve of 6 months before door to needle time ≤60 minutes returned to similar rates as the pre-CTA/CTP protocol.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Ali Reza Noorian, Katja Bryant, Ashley Aiken, Andrew D. Nicholson, Adam B. Edwards, Mason P. Markowski, Seena Dehkharghani, Jemisha C. Bouloute, Jacquelyn Abney, Fadi Nahab Tags: Original Articles Source Type: research

Racial and Socioeconomic Disparities in Access to Mechanical Revascularization Procedures for Acute Ischemic Stroke
Background: Mechanical revascularization procedures performed for treatment of acute ischemic stroke have increased in recent years. Data suggest association between operative volume and mortality rates. Understanding procedural allocation and patient access patterns is critical. Few studies have examined these demographics.Methods: Data were collected from the 2008 Nationwide Inpatient Sample database. Patients hospitalized with ischemic stroke and the subset of individuals who underwent mechanical thrombectomy were characterized by race, payer source, population density, and median wealth of the patient's zip code. Demog...
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: Frank J. Attenello, Peter Adamczyk, Ge Wen, Shuhan He, Katie Zhang, Jonathan J. Russin, Nerses Sanossian, Arun P. Amar, William J. Mack Tags: Original Articles Source Type: research

The Barrow Neurological Institute Screen for Higher Cerebral Functions in Cognitive Screening after Stroke
The objective of this study was to evaluate the Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS) in screening for cognitive dysfunction at long-term follow-up after stroke in young and middle-aged patients. Within the Sahlgrenska Academy Study on Ischemic Stroke Outcome, the BNIS and the Mini-Mental State Examination (MMSE) were administered to 295 consecutive surviving patients seven years after ischemic stroke. All participants were less than 70 years at index stroke. BNIS score less than 47 and an MMSE score less than 29 were chosen to indicate cognitive dysfunction. Two hundred eighty-one (95%...
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2013 Category: Neurology Authors: Petra Redfors, Caisa Hofgren, Ingrid Eriksson, Lukas Holmegaard, Hans Samuelsson, Katarina Jood Tags: Original Articles Source Type: research