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Source: Journal of Stroke and Cerebrovascular Diseases

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Informing Patients with Acute Stroke About their Risk of Dementia: A Survey of UK Healthcare Professionals
People who have a stroke are at an increased risk of developing dementia.1,2 According to the 2021 James Lind Alliance –Stroke Association Priority Setting Partnership, cognitive issues after stroke are a key concern of people who have a stroke.3 Identifying which patients with acute stroke are at risk of dementia could help patients and their carers to plan for the future. However, informing a patient who has jus t had a stroke about their risk of dementia may cause anxiety.
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2022 Category: Neurology Authors: Emily L. Ball, Gillian E. Mead, Eugene Y.H. Tang, Dorota Religa, Terence J. Quinn, Susan D. Shenkin Source Type: research

Transition in Incidence Rate of Hospitalised Stroke and Case Fatality Rate in the Hunter Region, Australia, 2001-2019: A Prospective Hospital-Based Study
Introduction: Continuous surveillance of stroke admissions has been conducted in the Hunter region, Australia, over the past two decades. We aimed to describe the trends in incidence rates of hospitalised stroke and case-fatality rates in this region, 2001-2019. Methods: From a hospital-based stroke registry, data for admitted adult stroke patients residing in the Hunter region were collected using ICD-10 codes for ischemic and haemorrhagic stroke. Negative binomial regression and logistic regression analysis were used to analyse trends for age-standardised and age-specific incidence rates of hospitalised stroke and 28-day...
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2022 Category: Neurology Authors: Yumi Tomari Kashida, Thomas Lillicrap, Rhonda Walker, Elizabeth Holliday, Md Golam Hasnain, Shinya Tomari, Carlos Garcia-Esperon, Jennifer J. Majersik, Neil J. Spratt, Christopher Levi Source Type: research

Undernutrition at Admission Suppresses Post-Stroke Recovery of Trunk Function
Stroke is one of the most common diseases worldwide, and 50%-85% of stroke patients show post-stroke impairments in motor function.1 Many patients require assistance with activities of daily living (ADL) after stroke due to weakness in arms and legs, which results in reduced walking and holding balance ability.2-4 The decreased post-stroke physical activity and motor function lead to reductions in cardiorespiratory fitness and muscle strength, resulting in further deterioration of ADL in patients with stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: Keisuke Sato, Tatsuro Inoue, Keisuke Maeda, Akio Shimizu, Junko Ueshima, Yuria Ishida, Takahiro Ogawa, Masaki Suenaga Source Type: research

Another possible determinant for ischemic stroke with nonvalvular atrial fibrillation other than conventional oral anticoagulant treatment: The relationship between whole blood viscosity and stroke ☆
Prevention of ischemic stroke complication of atrial fibrillation (AF) is the crucial target in the disease. Stroke is largely prevented by warfarin and the introduction of new oral anticoagulants. While warfarin reduces stroke by 60 –70%, new oral anticoagulants provide at least equal success to this reduction with appropriate dose and treatment compliance.1,2 Nonetheless, we still encounter thromboembolic ischemic stroke in clinical practice in AF patients taking oral anticoagulants (OAC) and once experienced, stroke can hav e devastating consequences for the patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2022 Category: Neurology Authors: Sezen Baglan Uzunget, Kader Eliz Sahin Source Type: research

Effect of metformin on outcome after acute ischemic stroke in patients with type 2 diabetes mellitus
Diabetes mellitus is a well-known risk factor for ischemic stroke and is associated with unfavorable outcome after stroke. Metformin is recommended as first-line treatment in these patients. Pre-stroke metformin use might have neuroprotective properties resulting in reduced stroke severity. However, results of the effects of pre-stroke metformin use on functional outcome are conflicting and has not been previously described in patients with type 2 diabetes mellitus regardless of stroke severity or revascularization treatment.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2022 Category: Neurology Authors: C.J.B.A. Kersten, I.L.H. Knottnerus, E. Heijmans, M. Haalboom, A.A.M. Zandbergen, H.M. den Hertog Source Type: research

Long-term determinants of death after stroke in Ghana: Analysis by stroke types & subtypes
Data on longer-term survival (>5 years) after stroke in sub-Saharan Africa (SSA) are limited in the literature. The prospects of survival after a stroke in SSA is of considerable interest given the steep rise in stroke burden,1,2 the relatively younger age of stroke onset and the under-resourced health care delivery on the continent. Poor short-term survival outcomes are well documented3,4 but there is a need for more longitudinal data to inform policy directives on resource allocation for stroke care.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2022 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Emmanuel Ofori, Bruce Ovbiagele Source Type: research

Post-stroke cognitive impairment and the risk of stroke recurrence and death in patients with insulin resistance
Post-stroke cognitive impairment (PSCI) is associated with etiology, severity, and functional outcome of stroke. The risks of recurrent stroke and death in patients with PSCI and insulin resistance (IR) is unknown. The goal of this study was to determine whether global and domain-specific cognitive impairment after stroke in patients with IR was associated with recurrent stroke and death.
Source: Journal of Stroke and Cerebrovascular Diseases - August 27, 2022 Category: Neurology Authors: Kat Schmidt, Melinda C. Power, Adam Ciarleglio, Zurab Nadareishvili, IRIS Study Group Source Type: research

Rationale and design of the AXIOMATIC-SSP phase II trial: Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events for Secondary Stroke Prevention
Early stroke occurrence after ischemic stroke or transient ischemic attack (TIA) remains a significant risk despite advances in secondary prevention. Ischemic stroke is largely a thromboembolic disease, and major efforts to reduce the early risk of recurrent stroke in patients with non-cardioembolic stroke have focused on antiplatelet strategies.1 Improvements in outcome have been associated with novel antiplatelet strategies, but significant residual risk of ischemic stroke and the potential for major bleeding, including intracranial hemorrhage, limit the effectiveness of these options.
Source: Journal of Stroke and Cerebrovascular Diseases - August 27, 2022 Category: Neurology Authors: Mukul Sharma, Carlos A. Molina, Kazunori Toyoda, Daniel Bereczki, Scott E. Kasner, Helmi L. Lutsep, Georgios Tsivgoulis, George Ntaios, Anna Czlonkowska, Ashfaq Shuaib, Pierre Amarenco, Matthias Endres, Hans Christoph Diener, David Gailani, Anja Kahl, Mar Source Type: research

The effects of combined early oral health care and early mobilisation on the incidence of stroke-associated pneumonia
Pneumonia after stroke, which influences mortality1 and duration of hospitalisation,2 has been a common critical issue in stroke patients. In 2015, the Pneumonia in Stroke Consensus Group proposed the diagnostic criteria of stroke-associated pneumonia (SAP), which is defined as a spectrum of lower respiratory tract infections in the first 7 days after stroke.3 A systematic review and meta-analysis reported that the incidence of SAP was 14%.4 There are several mechanisms of SAP onset, such as aspiration related to consciousness disturbance and dysphagia, stroke-induced immunodepression due to pathogenic bacteria, and immunological changes.
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2022 Category: Neurology Authors: Ayaka Fujita, Manabu Iwata, Joji Hagii, Norifumi Metoki, Hiroshi Shiroto, Eiichi Tsuda Source Type: research

Stroke survivors ’ preferences for post-stroke self-management programs: A discrete choice experiment
Stroke is a leading cause of serious, long-term disability with physical, emotional, social, and financial consequences that affect both stroke survivors as well as their families. Stroke has an incidence rate of 1.8 per 1000 person-years and a prevalence of 3.7% in Singapore1, and a 2015 report showed that stroke and other cerebrovascular diseases were the 10th most common cause of hospitalization and the 4th leading cause of deaths in the country.2 Further, stroke survivors are at a higher risk of having a transient ischemic attack (TIA),3 or another cerebrovascular attack.
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2023 Category: Neurology Authors: Kinjal Doshi, Stacey Lee Henderson, Denise Ju Ling Seah, Deidre Anne De Silva, Jia Jia Lee, Vinh Anh Huynh, Semra Ozdemir Source Type: research

ASOC Osuntokun Award Lecture 2022: Partnership for stroke prevention and treatment in Africa: Qualitative research processes and findings
Africa has one of the highest rates of stroke and stroke deaths in the world. The burden of stroke is increasing with a 3-year mortality rate of up to 84%. Stroke disproportionately affects the young and middle-aged population contributing to morbidity and mortality affecting families, communities, health systems, and economic progress. My objectives of the 2022 Osuntokun Award Lecture at the African Stroke Organization Conference were to explore our qualitative research findings from our communities and to propose future qualitative methods for improving stroke outcomes in Africa.
Source: Journal of Stroke and Cerebrovascular Diseases - March 2, 2023 Category: Neurology Authors: Carolyn Jenkins Source Type: research

Do kinematic measures, added to clinical measures, better predict upper extremity motor impairments at three months post-stroke?
Stroke is a prevalent worldwide cause of serious physical impairment. Due to the intricacy of movements needed for everyday life and the fact that motor recovery is typically delayed and less complete, stroke-related motor deficits in the upper extremity (UE) are particularly challenging to rehabilitate.1 At the time of stroke, the majority of survivors reported some degree of stroke-related paresis,2 and 25% of them reported difficulties using the affected UE even 5 years after a stroke.3 These arm and hand impairments contribute toward activity limitations and participation restrictions4, which eventually lead to a signi...
Source: Journal of Stroke and Cerebrovascular Diseases - July 13, 2023 Category: Neurology Authors: Sanjukta Sardesai, John M Solomon, A Sulfikar Ali, Ashokan Arumugam, Elton Dylan Nazareth, Aparna S Pai, Vasudeva Guddattu, Senthil Kumaran D Source Type: research

Gastroesophageal Reflux during Enteral Feeding in Stroke Patients: A 24-hour Esophageal pH-monitoring Study
Conclusions: GER is associated with aspiration pneumonia and occurs more often in patients with stroke lesions in the left hemisphere.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2011 Category: Neurology Authors: Yukie Satou, Hiroaki Oguro, Yo Murakami, Keiichi Onoda, Shingo Mitaki, Chizuko Hamada, Ryo Mizuhara, Shuhei Yamaguchi Tags: Original Articles Source Type: research

Association between Inflammatory Biomarkers and Progression of Intracranial Large Artery Stenosis after Ischemic Stroke
Conclusions: In addition to traditional risk factors and baseline radiologic findings, circulating levels of IL-6 measured soon after stroke onset are associated with future ILA progression.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2011 Category: Neurology Authors: Kanako Shimizu, Kana Shimomura, Yoshiaki Tokuyama, Kenzo Sakurai, Kenji Isahaya, Satoshi Takaishi, Bunta Kato, Noriko Usuki, Takahiro Shimizu, Koji Yamada, Yasuhiro Hasegawa Tags: Original Articles Source Type: research

Long-Term Follow-up of Incidental Intracranial Aneurysms in Patients with Acute Ischemic Stroke
Conclusions: In our study, the prevalence of incidental aneurysm among acute ischemic stroke patients was 6.1%. After 2 years of follow-up, there was no aneurysm rupture or subarachnoid hemorrhage, and the diameter and shape of aneurysms did not change except for 1 patient in whom the aneurysm disappeared.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2011 Category: Neurology Authors: Yoon-Sang Oh, Young-Min Shon, Beum Saeng Kim, A-Hyun Cho Tags: Original Articles Source Type: research