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Source: Current Pharmaceutical Design

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Total 176 results found since Jan 2013.

Clinical Efficacy of the Huo Xue Hua Yu Method Combined with Aspirin in the Treatment of Acute Cerebral Infarction: A systematic evaluation and Meta-Analysis
CONCLUSION: The combination of the Huo Xue Hua Yu method and aspirin represents a beneficial adjunctive therapy for ACI.PMID:37349997 | DOI:10.2174/1381612829666230622110753
Source: Current Pharmaceutical Design - June 23, 2023 Category: Drugs & Pharmacology Authors: Chu Chen Fang Ma Xinli Wen Xing Liu Qing Tang Yilun Wu Source Type: research

Potential Biomarkers and Therapeutic Targets: Inflammation and Oxidative Stress in Left Carotid Artery Stenosis with Coronary Artery Disease
CONCLUSION: Our observations indicated that measurements of oxidative stress and inflammatory markers may be valuable for the assessment of the degree of carotid with coronary artery stenosis. The biomarkers of oxidative stress and inflammatory response may become therapeutic targets for carotid artery stenosis with coronary artery stenosis in patients.PMID:37073146 | DOI:10.2174/1381612829666230417100144
Source: Current Pharmaceutical Design - April 17, 2023 Category: Drugs & Pharmacology Authors: Xia Li Dianxuan Guo Youdong Hu Hu Hualan Zhou Ying Chen Source Type: research

Tetramethylpyrazine Attenuates Oxygen-glucose Deprivation-induced Neuronal Damage through Inhibition of the HIF-1 α/BNIP3 Pathway: From Network Pharmacological Finding to Experimental Validation
CONCLUSION: Our study shows that TMP protects OGD-damaged PC12 cells by inhibiting the HIF-1α/BNIP3 pathway, which provides new insights into the mechanism of TMP and its neuroprotective potential.PMID:36790003 | DOI:10.2174/1381612829666230215100507
Source: Current Pharmaceutical Design - February 15, 2023 Category: Drugs & Pharmacology Authors: Shixin Xu Nannan Zhang Lanlan Cao Lu Liu Hao Deng Shengyu Hua Yunsha Zhang Source Type: research

Сhronically Administered BDNF Dipeptide Mimetic GSB-106 Prevents the Depressive-like Behavior and Memory Impairments after Transient Middle Cerebral Occlusion in Rats
Conclusion. The BDNF dipeptide mimetic GSB-106 is promising for further development as a drug for the treatment of poststroke neuropsychiatric disorders.PMID:36597610 | DOI:10.2174/1381612829666230103161824
Source: Current Pharmaceutical Design - January 4, 2023 Category: Drugs & Pharmacology Authors: Polina Yu Povarnina Tatyana A Antipova Ilya O Logvinov Tatiana A Gudasheva Sergey B Seredenin Source Type: research