Tetramethylpyrazine Attenuates Oxygen-glucose Deprivation-induced Neuronal Damage through Inhibition of the HIF-1 α/BNIP3 Pathway: From Network Pharmacological Finding to Experimental Validation

CONCLUSION: Our study shows that TMP protects OGD-damaged PC12 cells by inhibiting the HIF-1α/BNIP3 pathway, which provides new insights into the mechanism of TMP and its neuroprotective potential.PMID:36790003 | DOI:10.2174/1381612829666230215100507
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Source Type: research