Filtered By:
Source: Stroke
Procedure: PET Scan
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 171 results found since Jan 2013.
DWI-ASPECTS (Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Scores) and DWI-FLAIR (Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery) Mismatch in Thrombectomy Candidates Brief Report
Conclusions—Agreement between clinicians assessing DWI-ASPECTS and DWI-FLAIR mismatch may not be sufficient to make repeatable clinical decisions in mechanical thrombectomy. The dichotomization of the DWI-ASPECTS (0–5 versus 0–6 or 0–6 versus 7–10) improved interrater and intrarater agreement, however, its relevance for patients selection for mechanical thrombectomy needs to be validated in a randomized trial.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Robert Fahed, Augustin Lecler, Candice Sabben, Naim Khoury, Celina Ducroux, Vanessa Chalumeau, Daniele Botta, Erwah Kalsoum, William Boisseau, Loic Duron, Dominique Cabral, Patricia Koskas, Azzedine Benaissa, Hasmik Koulakian, Michael Obadia, Benȷa Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Brief Reports Source Type: research
Prevalence and Natural History of Superficial Siderosis Clinical Sciences
This study aimed to report the prevalence and natural history of SS in a population-based study.Methods—Brain magnetic resonance imaging scans from the MCSA (Mayo Clinic Study of Aging), a population-based study of residents 50 to 89 years of age in Olmsted County, Minnesota, were reviewed. Participants with imaging consistent with SS were identified from 2011 through 2016. An inverse probability weighting approach was used to convert our observed frequencies to population prevalence of SS. Additional data abstracted included amyloid positron emission tomography, Apolipoprotein E genotype, coexisting cerebral microbleeds...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Michael Pichler, Prashanthi Vemuri, Alejandro A. Rabinstein, Jeremiah Aakre, Kelly D. Flemming, Robert D. Brown Jr, Neeraj Kumar, Kejal Kantarci, Walter Kremers, Michelle M. Mielke, David S. Knopman, Clifford R. Jack Jr, Ronald C. Petersen, Val Lowe, Jona Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research
Neuroimaging Correlates of Cerebral Microbleeds Clinical Sciences
Conclusions—CMBs are a common vascular pathology in the elderly. Markers of hypertensive small-vessel disease may contribute to deep CMBs while cerebral amyloid angiopathy may drive development of lobar CMBs.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Jonathan Graff-Radford, Jeannette Simino, Kejal Kantarci, Thomas H. Mosley Jr, Michael E. Griswold, B. Gwen Windham, A. Richey Sharrett, Marilyn S. Albert, Rebecca F. Gottesman, Clifford R. Jack Jr, Prashanthi Vemuri, David S. Knopman Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Atherosclerosis Original Contributions Source Type: research
Island Sign Clinical Sciences
Conclusions—The island sign is a reliable CT imaging marker that independently predicts hematoma expansion and poor outcome in patients with ICH. The noncontrast CT island sign may serve as a potential marker for therapeutic intervention.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Qi Li, Qing-Jun Liu, Wen-Song Yang, Xing-Chen Wang, Li-Bo Zhao, Xin Xiong, Rui Li, Du Cao, Dan Zhu, Xiao Wei, Peng Xie Tags: Intracranial Hemorrhage Original Contributions Source Type: research
Long-Delay Arterial Spin Labeling Provides More Accurate Cerebral Blood Flow Measurements in Moyamoya Patients Clinical Sciences
Background and Purpose—Arterial spin labeling (ASL) MRI is a promising, noninvasive technique to image cerebral blood flow (CBF) but is difficult to use in cerebrovascular patients with abnormal, long arterial transit times through collateral pathways. To be clinically adopted, ASL must first be optimized and validated against a reference standard in these challenging patient cases.Methods—We compared standard-delay ASL (post-label delay=2.025 seconds), multidelay ASL (post-label delay=0.7–3.0 seconds), and long-label long-delay ASL acquisitions (post-label delay=4.0 seconds) against simultaneous [15O]-positron emiss...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Audrey P. Fan, Jia Guo, Mohammad M. Khalighi, Praveen K. Gulaka, Bin Shen, Jun Hyung Park, Harsh Gandhi, Dawn Holley, Omar Rutledge, Prachi Singh, Tom Haywood, Gary K. Steinberg, Frederick T. Chin, Greg Zaharchuk Tags: Magnetic Resonance Imaging (MRI), Nuclear Cardiology and PET, Moyamoya Original Contributions Source Type: research
Predictors for Cerebral Edema in Acute Ischemic Stroke Treated With Intravenous Thrombolysis Clinical Sciences
Background and Purpose—Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with intravenous thrombolysis.Methods—We used an image-based classification of CED with 3 degrees of severity (less severe CED 1 and most severe CED 3) on postintravenous thrombolysis imaging scans. We extracted data from 42 187 patients recorded in the SITS International Register (Safe Implementation of Trea...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Magnus Thoren, Elsa Azevedo, Jesse Dawson, Jose A. Egido, Anne Falcou, Gary A. Ford, Staffan Holmin, Robert Mikulik, Jyrki Ollikainen, Nils Wahlgren, Niaz Ahmed Tags: Risk Factors, Imaging, Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis Clinical Sciences
Background and Purpose—We assessed whether the presence, number, and distribution of cerebral microbleeds (CMBs) on pre-intravenous thrombolysis MRI scans of acute ischemic stroke patients are associated with an increased risk of intracerebral hemorrhage (ICH) or poor functional outcome.Methods—We performed an individual patient data meta-analysis, including prospective and retrospective studies of acute ischemic stroke treated with intravenous tissue-type plasminogen activator. Using multilevel mixed-effects logistic regression, we investigated associations of pre-treatment CMB presence, burden (1, 2–4, ≥5, and>10...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Andreas Charidimou, Guillaume Turc, Catherine Oppenheim, Shenqiang Yan, Jan F. Scheitz, Hebun Erdur, Pascal P. Klinger–Gratz, Marwan El–Koussy, Wakoh Takahashi, Yusuke Moriya, Duncan Wilson, Chelsea S. Kidwell, Jeffrey L. Saver, Asma Sallem, S Tags: Magnetic Resonance Imaging (MRI), Prognosis, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Noninvasive Assessment of Oxygen Extraction Fraction in Chronic Ischemia Using Quantitative Susceptibility Mapping at 7 Tesla Clinical Sciences
Conclusions—OEF ratios on QSM-OEF images at 7 Tesla showed a good correlation with those on PET-OEF images in patients with unilateral steno-occlusive internal carotid artery/middle cerebral artery lesions, suggesting that noninvasive OEF measurement by MRI can be a substitute for PET.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Ikuko Uwano, Kohsuke Kudo, Ryota Sato, Kuniaki Ogasawara, Hiroyuki Kameda, Jun-ichi Nomura, Futoshi Mori, Fumio Yamashita, Kenji Ito, Kunihiro Yoshioka, Makoto Sasaki Tags: Hemodynamics, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research
In-Patient Code Stroke Clinical Sciences
Conclusions—Our study reveals the efficacy of an inpatient code stroke algorithm and educational intervention directed at nurses and allied health personnel to optimize the prompt management of inpatient strokes. Prompt assessment may lead to faster stroke interventions, which are associated with better outcomes.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Charles D. Kassardjian, Jacqueline D. Willems, Krystyna Skrabka, Rosane Nisenbaum, Judith Barnaby, Pawel Kostyrko, Daniel Selchen, Gustavo Saposnik Tags: Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Multiparametric Model for Penumbral Flow Prediction in Acute Stroke Clinical Sciences
In this study, we established a multiparametric perfusion imaging model and cross-validated it using positron emission tomography perfusion for detection of penumbral flow.Methods—In a retrospective analysis of 17 subacute stroke patients with consecutive magnetic resonance imaging and H2O15 positron emission tomography scans, perfusion maps of cerebral blood flow, cerebral blood volume, mean transit time, time-to-maximum, and time-to-peak were constructed and combined using a generalized linear model (GLM). Both the GLM maps and the single perfusion maps alone were cross-validated with positron emission tomography-cereb...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Michelle Livne, Tabea Kossen, Vince I. Madai, Olivier Zaro-Weber, Walter Moeller-Hartmann, Kim Mouridsen, Wolf-Dieter Heiss, Jan Sobesky Tags: Imaging, Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research
Exacerbation of Thromboinflammation by Hyperglycemia Precipitates Cerebral Infarct Growth and Hemorrhagic Transformation Basic Sciences
Conclusions—We show that hyperglycemia primes the thromboinflammatory cascade, thus, amplifying middle cerebral artery occlusion–induced DMT. DMT exacerbation in hyperglycemic rats impaired reperfusion and precipitated neurovascular damage, blood–brain barrier disruption, and hemorrhagic transformation. Our results designate DMT as a possible target for reduction of the deleterious impact of hyperglycemia in acute ischemic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Jean–Philippe Desilles, Varouna Syvannarath, Veronique Ollivier, Clement Journe, Sandrine Delbosc, Celina Ducroux, William Boisseau, Liliane Louedec, Lucas Di Meglio, Stephane Loyau, Martine Jandrot–Perrus, Louis Potier, Jean–Baptiste Mi Tags: Biomarkers, Inflammation, Pathophysiology, Blood-Brain Barrier, Ischemic Stroke Original Contributions Source Type: research
Clinical Correlates, Ethnic Differences, and Prognostic Implications of Perivascular Spaces in Transient Ischemic Attack and Ischemic Stroke Clinical Sciences
Background and Purpose—Perivascular spaces (PVSs) are considered markers of small vessel disease. However, their long-term prognostic implications in transient ischemic attack/ischemic stroke patients are unknown. Ethnic differences in PVS prevalence are also unknown.Methods—Two independent prospective studies were conducted, 1 comprising predominantly whites with transient ischemic attack/ischemic stroke (OXVASC [Oxford Vascular] study) and 1 comprising predominantly Chinese with ischemic stroke (University of Hong Kong). Clinical and imaging correlates, prognostic implications for stroke and death, and ethnic differe...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Kui–Kai Lau, Linxin Li, Caroline E. Lovelock, Giovanna Zamboni, Tsz–Tai Chan, Man–Fung Chiang, Kin–Ting Lo, Wilhelm Kuker, Henry Ka–Fung Mak, Peter M. Rothwell Tags: Imaging, Magnetic Resonance Imaging (MRI), Prognosis, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Focal Macroscopic Cortical Lesions in Cerebral Autosomal-Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Brief Report
Conclusions—Focal macroscopic cortical lesions can be detected using specific magnetic resonance imaging approaches in CADASIL patients long before the end stage of the disorder. The underlying mechanisms and precise clinical consequences of these cortical changes still need to be determined.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Aicha Lyoubi–Idrissi, Francois De Guio, Hugues Chabriat, Eric Jouvent Tags: Imaging, Magnetic Resonance Imaging (MRI), CADASIL, Cerebrovascular Disease/Stroke Brief Reports Source Type: research
Baseline Hemodynamic Impairment and Future Stroke Risk in Adult Idiopathic Moyamoya Phenomenon Clinical Sciences
Conclusions—The risk of new or recurrent stroke was lower than expected. The low event rate, low prevalence of increased OEF, and potential selection bias introduced by revascularization surgery limit strong conclusions about the association of increased OEF and future stroke risk.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00629915.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Colin P. Derdeyn, Gregory J. Zipfel, Allyson R. Zazulia, Patricia H. Davis, Shyam Prabhakaran, Cristina S. Ivan, Venkatesh Aiyagari, James R. Sagar, Nancy Hantler, Lina Shinawi, John J. Lee, Hussain Jafri, Robert L. Grubb Jr, J. Philip Miller, Ralph G. Da Tags: Ischemic Stroke, Moyamoya Original Contributions Source Type: research
Predictive Value of RAPID Assessed Perfusion Thresholds on Final Infarct Volume in SWIFT PRIME (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment) Clinical Sciences
Conclusions—Brain regions with rCBF 0.30 to 0.34 or rCBV 0.32 to 0.34 thresholds provided the most accurate prediction of infarct volume in patients who achieved complete reperfusion with MAEs of ≤9 mL.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01657461.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Maxim Mokin, Elad I. Levy, Jeffrey L. Saver, Adnan H. Siddiqui, Mayank Goyal, Alain Bonafe, Christophe Cognard, Reza Jahan, Gregory W. Albers Tags: Computerized Tomography (CT), Ischemic Stroke Original Contributions Source Type: research
