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Source: Stroke
Procedure: PET Scan

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Total 171 results found since Jan 2013.

Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Scientific Statement
Two decades of epidemiological research shows that silent cerebrovascular disease is common and is associated with future risk for stroke and dementia. It is the most common incidental finding on brain scans. To summarize evidence on the diagnosis and management of silent cerebrovascular disease to prevent stroke, the Stroke Council of the American Heart Association convened a writing committee to evaluate existing evidence, to discuss clinical considerations, and to offer suggestions for future research on stroke prevention in patients with 3 cardinal manifestations of silent cerebrovascular disease: silent brain infarcts...
Source: Stroke - January 22, 2017 Category: Neurology Authors: Eric E. Smith, Gustavo Saposnik, Geert Jan Biessels, Fergus N. Doubal, Myriam Fornage, Philip B. Gorelick, Steven M. Greenberg, Randall T. Higashida, Scott E. Kasner, Sudha Seshadri Tags: Statements and Guidelines AHA/ASA Scientific Statement Source Type: research

Incidence, Locations, and Longitudinal Course of Cerebral Microbleeds in European Moyamoya Clinical Sciences
Background and Purpose—Cerebral microbleeds (cMBs) have previously been linked with especially high incidence in Asian patients with moyamoya together with high tendency to bleed. This, presumably, is characteristic of patients with moyamoya. Herein, we, therefore, investigate retrospectively the frequency, location, and longitudinal course of cMBs in a large German cohort.Methods—We included all patients with moyamoya who underwent standard magnetic resonance imaging, including T2*-weighted images, in our department between 1998 and 2015. Two independent readers evaluated magnetic resonance imaging scans to determine ...
Source: Stroke - January 22, 2017 Category: Neurology Authors: Holger Wenz, Ralf Wenz, Mate Maros, Gregory Ehrlich, Mansour Al–Zghloul, Christoph Groden, Alex Forster Tags: Imaging, Magnetic Resonance Imaging (MRI), Vascular Disease Original Contributions Source Type: research

Intracranial Carotid Artery Calcification Relates to Recanalization and Clinical Outcome After Mechanical Thrombectomy Clinical Sciences
Conclusions—A larger amount of ICAC before mechanical thrombectomy in acute stroke patients is an indicator of worse postprocedural arterial revascularization and poorer functional outcome.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Maria Hernandez–Perez, Daniel Bos, Laura Dorado, Karliȷn Pellikaan, Meike W. Vernooiȷ, Elena Lopez–Cancio, Natalia Perez de la Ossa, Meritxell Gomis, Carlos Castano, Josep Munuera, Josep Puig, Monica Millan, Antoni Davalos Tags: Computerized Tomography (CT), Imaging, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Lipid Changes Around the Final Menstrual Period Predict Carotid Subclinical Disease in Postmenopausal Women Clinical Sciences
Conclusions—Changes in lipids as women approach the FMP provide useful clinical information for understanding postmenopausal carotid indices.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Karen A. Matthews, Samar R. El Khoudary, Maria M. Brooks, Carol A. Derby, Sioban D. Harlow, Emma J.M. Barinas–Mitchell, Rebecca C. Thurston Tags: Epidemiology, Women, Atherosclerosis, Coronary Artery Disease Original Contributions Source Type: research

Prediction of Blood-Brain Barrier Disruption and Intracerebral Hemorrhagic Infarction Using Arterial Spin-Labeling Magnetic Resonance Imaging Clinical Sciences
Background and Purpose—Arterial spin-labeling magnetic resonance imaging is sensitive for detecting hyperemic lesions (HLs) in patients with acute ischemic stroke. We evaluated whether HLs could predict blood–brain barrier (BBB) disruption and hemorrhagic transformation (HT) in acute ischemic stroke patients.Methods—In a retrospective study, arterial spin-labeling was performed within 6 hours of symptom onset before revascularization treatment in 25 patients with anterior circulation large vessel occlusion on baseline magnetic resonance angiography. All patients underwent angiographic procedures intended for endovasc...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Takeya Niibo, Hajime Ohta, Shirou Miyata, Ichiro Ikushima, Kazuchika Yonenaga, Hideo Takeshima Tags: Imaging, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Quantification of Serial Cerebral Blood Flow in Acute Stroke Using Arterial Spin Labeling Clinical Sciences
Background and Purpose—Perfusion-weighted imaging is used to select patients with acute ischemic stroke for intervention, but knowledge of cerebral perfusion can also inform the understanding of ischemic injury. Arterial spin labeling allows repeated measurement of absolute cerebral blood flow (CBF) without the need for exogenous contrast. The aim of this study was to explore the relationship between dynamic CBF and tissue outcome in the month after stroke onset.Methods—Patients with nonlacunar ischemic stroke underwent ≤5 repeated magnetic resonance imaging scans at presentation, 2 hours, 1 day, 1 week, and 1 month....
Source: Stroke - December 22, 2016 Category: Neurology Authors: George W.J. Harston, Thomas W. Okell, Fintan Sheerin, Ursula Schulz, Phil Mathieson, Ian Reckless, Kunal Shah, Gary A. Ford, Michael A. Chappell, Peter Jezzard, James Kennedy Tags: Ischemic Stroke Original Contributions Source Type: research

Frequency and Predictors of Dysphagia in Patients With Recent Small Subcortical Infarcts Brief Report
Background and Purpose—Detailed data on the occurrence of swallowing dysfunction in patients with recent small subcortical infarcts (RSSI) in the context of cerebral small vessel disease are lacking. This prompted us to assess the frequency of and risk factors for dysphagia in RSSI patients.Methods—We identified all inpatients with magnetic resonance imaging–confirmed RSSI between January 2008 and February 2013. Demographic and clinical data were extracted from our stroke database, and magnetic resonance imaging scans were reviewed for morphological changes. Dysphagia was determined according to the Gugging Swallowin...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Simon Fandler, Thomas Gattringer, Sebastian Eppinger, Kathrin Doppelhofer, Daniela Pinter, Kurt Niederkorn, Christian Enzinger, Joanna M. Wardlaw, Franz Fazekas Tags: Magnetic Resonance Imaging (MRI), Complications, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial) Clinical Sciences
Conclusions—We found an association between right insular involvement and higher odds of death and worse functional outcome. The difference between right- and left-sided insular lesions on outcomes seemed to be most evident for mild/moderate strokes.Clinical Trial Registration—URL: http://www.isrctn.com. Unique identifier: ISRCTN25765518.
Source: Stroke - November 27, 2016 Category: Neurology Authors: Luciano A. Sposato, Geoffrey Cohen, Joanna M. Wardlaw, Peter Sandercock, Richard I. Lindley, Vladimir Hachinski, on behalf of the IST-3 Expert Reading Panel and the IST-3 Collaborative Group Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Optimal Computed Tomographic Perfusion Scan Duration for Assessment of Acute Stroke Lesion Volumes Clinical Sciences
Background and Purpose—The minimal scan duration needed to obtain reliable lesion volumes with computed tomographic perfusion (CTP) has not been well established in the literature.Methods—We retrospectively assessed the impact of gradual truncation of the scan duration on acute ischemic lesion volume measurements. For each scan, we identified its optimal scan time, defined as the shortest scan duration that yields measurements of the ischemic lesion volumes similar to those obtained with longer scanning, and the relative height of the fitted venous output function at its optimal scan time.Results—We analyzed 70 compu...
Source: Stroke - November 27, 2016 Category: Neurology Authors: Aimen S. Kasasbeh, Soren Christensen, Matus Straka, Nishant Mishra, Michael Mlynash, Roland Bammer, Gregory W. Albers, Maarten G. Lansberg Tags: Computerized Tomography (CT), Ischemic Stroke Original Contributions Source Type: research

Prevalence of Amyloid Positron Emission Tomographic Positivity in Poststroke Mild Cognitive Impairment Brief Reports
Conclusions— The prevalence of amyloid-pathology in patients with PS-MCI is not increased when compared with cognitively healthy stroke survivors and to recent estimates for cognitively healthy elderly subjects. Factors other than amyloid-pathology likely contribute to the development of PS-MCI. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01334749.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Wollenweber, F. A., Darr, S., Muller, C., Duering, M., Buerger, K., Zietemann, V., Malik, R., Brendel, M., Ertl-Wagner, B., Bartenstein, P., Rominger, A., Dichgans, M. Tags: Magnetic Resonance Imaging (MRI), Nuclear Cardiology and PET, Cerebrovascular Disease/Stroke, Cognitive Impairment Brief Reports Source Type: research

Increased Frontal Lobe Activation After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions— We have shown increased activation in areas of the anterior cingulate gyrus and frontobasal regions during the execution of more demanding tasks in good grade. The degree of activation in the anterior cingulate gyrus has a negative correlation with cognitive (Montreal Cognitive Assessment) scores. These subtle differences may be related to the common neurocognitive and behavioral complaints seen in this patient population.
Source: Stroke - September 25, 2016 Category: Neurology Authors: da Costa, L., Dunkley, B. T., Bethune, A., Robertson, A., Keller, A., Pang, E. W. Tags: Imaging, Prognosis, Cerebral Aneurysm, Intracranial Hemorrhage Clinical Sciences Source Type: research

Remote Lower White Matter Integrity Increases the Risk of Long-Term Cognitive Impairment After Ischemic Stroke in Young Adults Clinical Sciences
Conclusions— These findings indicate that although stroke has an acute onset, it might have long lasting effects on remote white matter integrity and thereby increases the risk of long-term cognitive impairment.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Schaapsmeerders, P., Tuladhar, A. M., Arntz, R. M., Franssen, S., Maaijwee, N. A. M., Rutten-Jacobs, L. C. A., Schoonderwaldt, H. C., Dorresteijn, L. D. A., van Dijk, E. J., Kessels, R. P. C., de Leeuw, F.-E. Tags: Magnetic Resonance Imaging (MRI), Cognitive Impairment, Ischemic Stroke Clinical Sciences Source Type: research

The Capillary Index Score as a Marker of Viable Cerebral Tissue: Proof of Concept--The Capillary Index Score in the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Trial Clinical Sciences
Conclusions— The absence of capillary blush on pretreatment digital subtraction angiogram seems to correspond to nonviable cerebral tissue. Successful revascularization reduces the chance of tissue hypodensity (infarction), when capillary blush is present. Clinical Trial Registration— URL: http://www.trialregister.nl. Unique identifier: NTR number 1804. URL: http://www.isrctn.com. Unique identifier: ISRCTN10888758.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Al-Ali, F., Berkhemer, O. A., Yousman, W. P., Elias, J. J., Bender, E. N., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Dillon, W. P., Majoie, C. B. L. M. Tags: Computerized Tomography (CT), Revascularization, Ischemic Stroke Clinical Sciences Source Type: research

Postmortem Study of Validation of Low Signal on Fat-Suppressed T1-Weighted Magnetic Resonance Imaging as Marker of Lipid Core in Middle Cerebral Artery Atherosclerosis Clinical Sciences
Conclusions— LST1 is a promising imaging biomarker of identifying intraplaque lipid core, which may be useful to distinguish intracranial atherosclerotic disease from other intracranial vasculopathies and to assess plaque vulnerability for risk stratification of patients with intracranial atherosclerotic disease. In vivo clinical studies are required to explore the correlation between LST1 and clinical outcomes of patients with intracranial atherosclerotic disease.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Yang, W.-J., Chen, X.-Y., Zhao, H.-L., Niu, C.-B., Zhang, B., Xu, Y., Wong, K.-S., Ng, H.-K. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Vascular Disease Clinical Sciences Source Type: research

Leukoaraiosis, Cerebral Hemorrhage, and Outcome After Intravenous Thrombolysis for Acute Ischemic Stroke: A Meta-Analysis (v1) Clinical Sciences
Conclusions— Leukoaraiosis might increase post-intravenous thrombolysis sICH risk and poor outcome poststroke. Despite increased sICH risk, intravenous tissue-type plasminogen activator treatment has net clinical benefit in patients with leukoaraiosis. Given the risk of bias/confounding, these results should be considered hypothesis-generating and do not justify withholding intravenous thrombolysis.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Charidimou, A., Pasi, M., Fiorelli, M., Shams, S., von Kummer, R., Pantoni, L., Rost, N. Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Clinical Sciences Source Type: research