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Source: Stroke
Procedure: PET Scan

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Total 171 results found since Jan 2013.

Stroke Patients Develop Antibodies That React With Components of N-Methyl-D-Aspartate Receptor Subunit 1 in Proportion to Lesion Size Clinical Sciences
Conclusions— Antibodies that bind recombinant GluN1-S2 peptides (but not the intact GluN1 protein) develop transiently in patients after stroke in proportion to infarct size, suggesting that these antibodies are raised secondarily to neuronal damage. The anti–GluN1-S2 antibodies may provide useful information about the presence and severity of cerebral infarction. This will require confirmation in larger studies.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Kalev-Zylinska, M. L., Symes, W., Little, K. C. E., Sun, P., Wen, D., Qiao, L., Young, D., During, M. J., Barber, P. A. Tags: Ischemic biology - basic studies, Other diagnostic testing Clinical Sciences Source Type: research

Effects of Noninvasive Brain Stimulation on Language Networks and Recovery in Early Poststroke Aphasia Clinical Sciences
Conclusions— Ten sessions of inhibitory rTMS over the right posterior inferior frontal gyrus, in combination with speech and language therapy, significantly improve language recovery in subacute ischemic stroke and favor recruitment of left-hemispheric language networks.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Thiel, A., Hartmann, A., Rubi-Fessen, I., Anglade, C., Kracht, L., Weiduschat, N., Kessler, J., Rommel, T., Heiss, W.-D. Tags: Behavioral Changes and Stroke, PET and SPECT, Rehabilitation, Stroke, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Spatiotemporal Uptake Characteristics of 18F-2-Fluoro-2-Deoxy-D-Glucose in a Rat Middle Cerebral Artery Occlusion Model Basic Sciences
Conclusions— Elevated FDG uptake at the peri-ischemic zone is consistently observed during acute cerebral ischemia. The region with elevated FDG uptake likely reflects viable tissues that can be salvaged with reperfusion. Therefore, acute FDG positron emission tomography imaging might hold promise in the management of patients with acute stroke.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Yuan, H., Frank, J. E., Hong, Y., An, H., Eldeniz, C., Nie, J., Bunevicius, A., Shen, D., Lin, W. Tags: Nuclear cardiology and PET, Acute Cerebral Infarction Basic Sciences Source Type: research

Clinical Outcomes Strongly Associated With the Degree of Reperfusion Achieved in Target Mismatch Patients: Pooled Data from the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution Studies Clinical Sciences
Conclusion— The degree of reperfusion documented on perfusion-weighted imaging after reperfusion therapies corresponds closely with clinical outcomes in TMM patients. Reperfusion of ≥90% of the perfusion lesion is an appropriate goal for reperfusion therapies to aspire to.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Inoue, M., Mlynash, M., Straka, M., Kemp, S., Jovin, T. G., Tipirneni, A., Hamilton, S. A., Marks, M. P., Bammer, R., Lansberg, M. G., Albers, G. W., for the DEFUSE 1 and 2 Investigators Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Effects of Candesartan in Acute Stroke on Cognitive Function and Quality of Life: Results From the Scandinavian Candesartan Acute Stroke Trial Brief Reports
Conclusions— Candesartan did not improve cognitive function or quality of life. Rather, there were signs of harmful effects. These findings support the conclusion from our previous report that there is no indication for routine blood pressure–lowering treatment with candesartan in the acute phase of stroke. Clinical Trial Registration— URL: www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Hornslien, A. G., Sandset, E. C., Bath, P. M., Wyller, T. B., Berge, E., on Behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cardiovascular Pharmacology, Cerebrovascular disease/stroke, Acute Stroke Syndromes, Other Stroke Treatment - Medical Brief Reports Source Type: research

Transcranial Laser Therapy and Infarct Volume Brief Reports
Conclusions— TLT was not associated with a reduction in overall or cortical infarct volume as measured on computed tomography in the subacute phase.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Kasner, S. E., Rose, D. Z., Skokan, A., Walker, M. G., Shi, J., Streeter, J., the NEST-2 Steering Committee and Investigators Tags: Acute Cerebral Infarction, Neuroprotectors Brief Reports Source Type: research

Accuracy and Clinical Usefulness of Intracerebral Hemorrhage Grading Scores: A Direct Comparison in a UK Population Clinical Sciences
Conclusions— Although existing grading scores are highly predictive of 30-day mortality, GCS alone was as predictive in our cohort, but age was not.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Parry-Jones, A. R., Abid, K. A., Di Napoli, M., Smith, C. J., Vail, A., Patel, H. C., King, A. T., Tyrrell, P. J. Tags: Acute Cerebral Hemorrhage, Intracerebral Hemorrhage Clinical Sciences Source Type: research

Autoregulation of Cerebral Blood Flow is Preserved in Primary Intracerebral Hemorrhage Brief Reports
Conclusions— CBF remained stable after acute BP reduction, suggesting some preservation of cerebral autoregulation.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Gould, B., McCourt, R., Asdaghi, N., Dowlatshahi, D., Jeerakathil, T., Kate, M., Coutts, S. B., Hill, M. D., Demchuk, A. M., Shuaib, A., Emery, D., Butcher, K., on behalf of the ICH ADAPT investigators Tags: Acute Cerebral Hemorrhage, Brain Circulation and Metabolism Brief Reports Source Type: research

Yield of Cather Angiography After Computed Tomography Negative, Lumbar Puncture Positive Subarachnoid Hemorrhage Brief Reports
Conclusions— Catheter angiography should be performed in patients with computed tomography negative but suspicious lumbar puncture, particularly in the presence of xanthochromia. The benefit of angiography in patients with erythrocytosis only is unclear and deserves future study.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Wallace, A. N., Dines, J. N., Zipfel, G. J., Derdeyn, C. P. Tags: CT and MRI, Angiography Brief Reports Source Type: research

Rating Method for Dilated Virchow-Robin Spaces on Magnetic Resonance Imaging Brief Reports
Conclusions— We describe a reliable rating method that can facilitate pathogenic and prognostic research on dilated Virchow–Robin spaces using MRI.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Adams, H. H. H., Cavalieri, M., Verhaaren, B. F. J., Bos, D., van der Lugt, A., Enzinger, C., Vernooij, M. W., Schmidt, R., Ikram, M. A. Tags: Brain Circulation and Metabolism, Computerized tomography and Magnetic Resonance Imaging Brief Reports Source Type: research

Thrombolysis Despite Recent Stroke: A Case Series Brief Reports
Conclusions— In our center, we thrombolysed 6 patients despite recent stroke. Three patients had asymptomatic petechial hemorrhagic transformation within the area of subacute infarct, without apparent neurological worsening. Prospective studies are needed to explore the possible safety of tissue-type plasminogen activator in the context of previous subacute stroke in otherwise eligible patients.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Alhazzaa, M., Sharma, M., Blacquiere, D., Stotts, G., Hogan, M., Dowlatshahi, D. Tags: Acute Cerebral Infarction, Thrombolysis Brief Reports Source Type: research

Minimally Invasive Surgery Plus Recombinant Tissue-type Plasminogen Activator for Intracerebral Hemorrhage Evacuation Decreases Perihematomal Edema Clinical Sciences
Conclusions— Hematoma evacuation is associated with significant reduction in PHE. Furthermore, PHE does not seem to be exacerbated by rt-PA, making such neurotoxic effects unlikely when the drug is delivered to intracranial clot.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Mould, W. A., Carhuapoma, J. R., Muschelli, J., Lane, K., Morgan, T. C., McBee, N. A., Bistran-Hall, A. J., Ullman, N. L., Vespa, P., Martin, N. A., Awad, I., Zuccarello, M., Hanley, D. F., for the MISTIE Investigators Tags: Acute Cerebral Hemorrhage, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

The Modified Graeb Score: An Enhanced Tool for Intraventricular Hemorrhage Measurement and Prediction of Functional Outcome Clinical Sciences
Conclusions— The mGS, a semiquantitative scale for IVH volume measurement, is a reliable measure with prognostic validity suitable for rapid use in clinical practice and in research.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Morgan, T. C., Dawson, J., Spengler, D., Lees, K. R., Aldrich, C., Mishra, N. K., Lane, K., Quinn, T. J., Diener-West, M., Weir, C. J., Higgins, P., Rafferty, M., Kinsley, K., Ziai, W., Awad, I., Walters, M. R., Hanley, D., the CLEAR and VISTA Investigato Tags: Acute Cerebral Hemorrhage, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Early Magnetic Resonance Imaging in Transient Ischemic Attack and Minor Stroke: Do it or Lose it Clinical Sciences
Conclusions— Delayed MRI after TIA or minor stroke reduces the diagnostic yield and results in missed understanding of the lesion pattern. MRI of minor stroke and TIA patients should occur early after symptom onset, and delayed imaging should be interpreted with caution.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Moreau, F., Modi, J., Almekhlafi, M., Bal, S., Goyal, M., Hill, M. D., Coutts, S. B. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Transient Ischemic Attacks Clinical Sciences Source Type: research

Early Diffusion-Weighted Imaging and Perfusion-Weighted Imaging Lesion Volumes Forecast Final Infarct Size in DEFUSE 2 Clinical Sciences
Conclusions— Baseline DWI and early follow-up PWI (Tmax >6 seconds) volumes provide a reasonable approximation of final infarct volume after endovascular therapy.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Wheeler, H. M., Mlynash, M., Inoue, M., Tipirneni, A., Liggins, J., Zaharchuk, G., Straka, M., Kemp, S., Bammer, R., Lansberg, M. G., Albers, G. W., on behalf of the DEFUSE 2 Investigators Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research