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Source: Stroke
Procedure: MRI Scan

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Total 526 results found since Jan 2013.

Hyperintense Vessels, Collateralization, and Functional Outcome in Patients With Stroke Receiving Endovascular Treatment Clinical Sciences
Conclusions—Low FHV-ASPECTS is associated with both better collateral status and better 3-month functional outcome in acute stroke patients with M1 vessel occlusion.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Alexander H. Nave, Anna Kufner, Philipp Bucke, Eberhard Siebert, Stefan Kliesch, Ulrike Grittner, Hansȷorg Bazner, Thomas Liebig, Matthias Endres, Jochen B. Fiebach, Christian H. Nolte, Martin Ebinger, Hans Henkes Tags: Angiography, Magnetic Resonance Imaging (MRI), Prognosis, Revascularization, Ischemic Stroke Original Contributions Source Type: research

Neuroprotective Effects of MAGL (Monoacylglycerol Lipase) Inhibitors in Experimental Ischemic Stroke Basic Sciences
Conclusions—Our results suggest that MAGL may contribute to the pathophysiology of focal cerebral ischemia and is thus a promising therapeutic target for the treatment of ischemic stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Sang-Ho Choi, Allison L. Arai, Yongshan Mou, Byeongteck Kang, Cecil Chern-Chyi Yen, John Hallenbeck, Afonso C. Silva Tags: Animal Models of Human Disease, Basic Science Research, Inflammation, Ischemic Stroke Original Contributions Source Type: research

Patients With Undetermined Stroke Have Increased Atrial Fibrosis Brief Report
Conclusions—The LA phenotype that was found in patients with undetermined cause supports the hypothesis that an atrial disease may be associated with stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Ana Catarina Fonseca, Pedro Alves, Nuno Inacio, Joao Pedro Marto, Miguel Viana–Baptista, Teresa Pinho–e–Melo, Jose M. Ferro, Ana G. Almeida Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Embolism Brief Reports Source Type: research

Reduced Intravoxel Incoherent Motion Microvascular Perfusion Predicts Delayed Cerebral Ischemia and Vasospasm After Aneurysm Rupture Brief Report
Conclusions—Decreased IVIM perfusion fraction f and blood flow–related parameter fD* correlate with DCI and proximal artery vasospasm development after cerebral aneurysm rupture.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Jeremy J. Heit, Max Wintermark, Blake W. Martin, Guangming Zhu, Michael P. Marks, Greg Zaharchuk, Robert L. Dodd, Huy M. Do, Gary K. Steinberg, Maarten G. Lansberg, Gregory W. Albers, Christian Federau Tags: Magnetic Resonance Imaging (MRI), Cerebral Aneurysm, Intracranial Hemorrhage, Aneurysm Brief Reports Source Type: research

Outcome After Reperfusion Therapies in Patients With Large Baseline Diffusion-Weighted Imaging Stroke Lesions Brief Report
Conclusions—Stroke patients with DWI lesion>70 mL may benefit from reperfusion therapy, especially those with isolated M1 occlusion or ischemia restricted to the superficial middle cerebral artery territory. The benefit of treatment seems questionable for patients with carotid occlusion or lesion extending to the deep middle cerebral artery territory.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Vincent Gautheron, Yu Xie, Marie Tisserand, Helene Raoult, Sebastien Soize, Olivier Naggara, Romain Bourcier, Sebastien Richard, Francis Guillemin, Serge Bracard, Catherine Oppenheim Tags: Magnetic Resonance Imaging (MRI), Prognosis, Revascularization, Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research

Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable Clinical Sciences
Conclusions—We provide evidence for important genetic contribution to dPVS burden in older community-dwelling people, some of which may be shared with WMHV. Differential heritability patterns for dPVS in white matter and basal ganglia suggest at least partly distinct underlying biological processes.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Marie–Gabrielle Duperron, Christophe Tzourio, Muralidharan Sargurupremraȷ, Bernard Mazoyer, Aicha Soumare, Sabrina Schilling, Philippe Amouyel, Ganesh Chauhan, Yi–Cheng Zhu, Stephanie Debette Tags: Aging, Epidemiology, Genetics, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Carotid Intima-Media Thickness Is Associated With White Matter Hyperintensities Clinical Sciences
Conclusions—Larger cIMT was associated with greater burden of cerebral WM lesions independently of demographics and traditional vascular risk factors, particularly among elderly and Hispanic participants, who are at high risk for stroke and cognitive decline.
Source: Stroke - January 22, 2018 Category: Neurology Authors: David Della-Morte, Chuanhui Dong, Matthew S. Markert, Mitchell S.V. Elkind, Ralph L. Sacco, Clinton B. Wright, Tatjana Rundek Tags: Epidemiology, Race and Ethnicity, Ultrasound Original Contributions Source Type: research

Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly Clinical Sciences
Conclusions—In a predominantly elderly cohort, elevated nighttime HR was associated with WMHV, suggesting an independent role of HR in subclinical cerebrovascular disease.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Koki Nakanishi, Zhezhen Jin, Shunichi Homma, Mitchell S.V. Elkind, Tatjana Rundek, Seitetz C. Lee, Aylin Tugcu, Mitsuhiro Yoshita, Charles DeCarli, Clinton B. Wright, Ralph L. Sacco, Marco R. Di Tullio Tags: Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Transient Ischemic Attack Results in Delayed Brain Atrophy and Cognitive Decline Clinical Sciences
Background and Purpose—Transient ischemic attack (TIA) initiates an ischemic cascade without resulting in frank infarction and, as such, represents a novel model to study the effects of this ischemic cascade and secondary neurodegeneration in humans.Methods—Patients with suspected TIA underwent acute brain perfusion imaging, and those with acute ischemia were enrolled into a prospective observational study. We collected baseline and 90-day magnetic resonance imaging, including MP-RAGE (high-resolution T1 sequence) and cognitive assessment with the Montreal Cognitive Assessment. Brain morphometry and within patient stat...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Andrew Bivard, Thomas Lillicrap, Benedicte Marechal, Carlos Garcia–Esperon, Elizabeth Holliday, Venkatesh Krishnamurthy, Christopher R. Levi, Mark Parsons Tags: Clinical Studies, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Cognitive Impairment, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Neuroimaging Identifies Patients Most Likely to Respond to a Restorative Stroke Therapy Clinical Sciences
Background and Purpose—Patient heterogeneity reduces statistical power in clinical trials of restorative therapies. Valid predictors of treatment responsiveness are needed, and several have been studied with a focus on corticospinal tract (CST) injury. We studied performance of 4 such measures for predicting behavioral gains in response to motor training therapy.Methods—Patients with subacute-chronic hemiparetic stroke (n=47) received standardized arm motor therapy, and change in arm Fugl-Meyer score was calculated from baseline to 1 month post-therapy. Injury measures calculated from baseline magnetic resonance imagin...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Jessica M. Cassidy, George Tran, Erin B. Quinlan, Steven C. Cramer Tags: Biomarkers, Imaging, Rehabilitation, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Diagnosis of Cerebral Amyloid Angiopathy Topical Review
Source: Stroke - January 22, 2018 Category: Neurology Authors: Steven M. Greenberg, Andreas Charidimou Tags: Diagnostic Testing, Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage Topical Reviews Source Type: research

Cognitive Impairment Before Intracerebral Hemorrhage Is Associated With Cerebral Amyloid Angiopathy Clinical Sciences
Conclusions—CAA (defined using magnetic resonance imaging markers) is associated with cognitive decline before symptomatic ICH. This provides evidence that small vessel disruption in CAA makes an independent contribution to cognitive impairment, in addition to effects due to brain injury caused directly by ICH.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT02513316.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Gargi Banerȷee, Duncan Wilson, Gareth Ambler, Karen Osei–Bonsu Appiah, Clare Shakeshaft, Surabhika Lunawat, Hannah Cohen, Tarek Yousry Dr, Gregory Y.H. Lip, Keith W. Muir, Martin M. Brown, Rustam Al–Shahi Salman, Hans Rolf Jager, David Tags: Cerebrovascular Disease/Stroke, Cognitive Impairment, Intracranial Hemorrhage Original Contributions Source Type: research

Factors Associated With Focal Computed Tomographic Perfusion Abnormalities in Supratentorial Transient Ischemic Attacks Clinical Sciences
Conclusions—Supratentorial TIAs are often associated with FPA in CTP, even after symptom resolution. FPAs are frequent in severe TIAs and those associated with cardioembolism or specific arterial pathologies. These findings can help clinicians in accurate diagnosis of TIA and its underlying mechanisms.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Ivo A. Meyer, Carlo W. Cereda, Pamela N. Correia, Jean-Baptiste Zerlauth, Francesco Puccinelli, David C. Rotzinger, Michael Amiguet, Philippe Maeder, Reto A. Meuli, Patrik Michel Tags: Computerized Tomography (CT), Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Cerebellar Hematoma Location Brief Report
Background and Purpose—Spontaneous cerebellar intracerebral hemorrhage (ICH) has been reported to be mainly associated with vascular changes secondary to hypertension. However, a subgroup of cerebellar ICH seems related to vascular amyloid deposition (cerebral amyloid angiopathy). We sought to determine whether location of hematoma in the cerebellum (deep and superficial regions) was suggestive of a particular hemorrhage-prone small-vessel disease pathology (cerebral amyloid angiopathy or hypertensive vasculopathy).Methods—Consecutive patients with cerebellar ICH from a single tertiary care medical center were recruite...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Marco Pasi, Sandro Marini, Andrea Morotti, Gregoire Boulouis, Li Xiong, Andreas Charidimou, Alison M. Ayres, Myung Joo Lee, Alessandro Biffi, Joshua N. Goldstein, Jonathan Rosand, M. Edip Gurol, Steven M. Greenberg, Anand Viswanathan Tags: Intracranial Hemorrhage Brief Reports Source Type: research

DWI-ASPECTS (Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Scores) and DWI-FLAIR (Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery) Mismatch in Thrombectomy Candidates Brief Report
Conclusions—Agreement between clinicians assessing DWI-ASPECTS and DWI-FLAIR mismatch may not be sufficient to make repeatable clinical decisions in mechanical thrombectomy. The dichotomization of the DWI-ASPECTS (0–5 versus 0–6 or 0–6 versus 7–10) improved interrater and intrarater agreement, however, its relevance for patients selection for mechanical thrombectomy needs to be validated in a randomized trial.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Robert Fahed, Augustin Lecler, Candice Sabben, Naim Khoury, Celina Ducroux, Vanessa Chalumeau, Daniele Botta, Erwah Kalsoum, William Boisseau, Loic Duron, Dominique Cabral, Patricia Koskas, Azzedine Benaissa, Hasmik Koulakian, Michael Obadia, Benȷa Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Brief Reports Source Type: research