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Source: Stroke
Procedure: MRI Scan

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Total 526 results found since Jan 2013.

Interactions Between the Corticospinal Tract and Premotor-Motor Pathways for Residual Motor Output After Stroke Clinical Sciences
Conclusions—The present data show that patients with stroke with different degree of CST disruption differ in their dependency on structural premotor–motor connections for residual motor output. This finding might have important implications for future research on recovery prediction models and on responses to treatment strategies.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Robert Schulz, Eunhee Park, Jungsoo Lee, Won Hyuk Chang, Ahee Lee, Yun-Hee Kim, Friedhelm C. Hummel Tags: Mechanisms, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Neurostimulation Original Contributions Source Type: research

Hemorrhagic Transformation After Large Cerebral Infarction in Rats Pretreated With Dabigatran or Warfarin Basic Sciences
Background and Purpose—It is uncertain whether hemorrhagic transformation (HT) after large cerebral infarction is less frequent in dabigatran users than warfarin users. We compared the occurrence of HT after large cerebral infarction among rats pretreated with dabigatran, warfarin, or placebo.Methods—This was a triple-blind, randomized, and placebo-controlled experiment. After treatment with warfarin (0.2 mg/kg), dabigatran (20 mg/kg), or saline for 7 days, Wistar rats were subjected to transient middle cerebral artery occlusion. As the primary outcome, HT was determined by gradient-recalled echo imaging. For the secon...
Source: Stroke - September 25, 2017 Category: Neurology Authors: Il Kwon, Sunho An, Jayoung Kim, Seung-Hee Yang, Joonsang Yoo, Jang-Hyun Baek, Hyo Suk Nam, Young Dae Kim, Hye Sun Lee, Hyun-Jung Choi, Ji Hoe Heo Tags: Magnetic Resonance Imaging (MRI), Anticoagulants, Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

White Matter Hyperintensity Volume and Outcome of Mechanical Thrombectomy With Stentriever in Acute Ischemic Stroke Brief Report
Conclusions—Mechanical thrombectomy using stentrievers seems to be safe in selected patients with acute ischemic stroke with large vessel occlusion, nonwithstanding the severity of WMH burden in this population. Larger prospective studies are warranted to validate these findings.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Kunakorn Atchaneeyasakul, Thabele Leslie-Mazwi, Kathleen Donahue, Anne-Katrin Giese, Natalia S. Rost Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Correction to: Effect of Long-Term Vascular Care on Progression of Cerebrovascular Lesions: Magnetic Resonance Imaging Substudy of the PreDIVA Trial (Prevention of Dementia by Intensive Vascular Care) Correction
Source: Stroke - August 28, 2017 Category: Neurology Tags: Corrections Source Type: research

Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General Population Clinical Sciences
Conclusions—Men are at greater risk of developing incident brain infarcts than women. Persons with incident brain infarcts decline faster in cognition and have an increased risk of dementia compared with those free of infarcts. Incident subcortical infarcts contribute more than cortical and cerebellar infarcts to incident dementia which may indicate that infarcts of small vessel disease origin contribute more to the development of dementia than infarcts of embolic origin in larger vessels.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Sigurdur Sigurdsson, Thor Aspelund, Olafur Kjartansson, Elias F. Gudmundsson, Maria K. Jonsdottir, Gudny Eiriksdottir, Palmi V. Jonsson, Mark A. van Buchem, Vilmundur Gudnason, Lenore J. Launer Tags: Epidemiology, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Vascular Disease Original Contributions Source Type: research

Vascular Risk Factor Profiles Differ Between Magnetic Resonance Imaging-Defined Subtypes of Younger-Onset Lacunar Stroke Clinical Sciences
Conclusions—In this magnetic resonance imaging–verified lacunar stroke population, we identified a distinct risk factor profile in the group as a whole. However, there were differing risk factor profiles according to the presence of multiple lacunar infarcts and confluent WMH. The association of hypertension, smoking, and renal impairment with the presence of multiple lacunar infarcts and confluent WMH might reflect a diffuse small vessel arteriopathy.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Loes C.A. Rutten-Jacobs, Hugh S. Markus Tags: Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Detection of Left Ventricular Thrombus by Cardiac Magnetic Resonance in Embolic Stroke of Undetermined Source Clinical Sciences
Background and Purpose—We aimed to use contrast-enhanced cardiac magnetic resonance (CE-CMR) imaging to elucidate the prevalence of left ventricular (LV) thrombus in patients suspected of embolic stroke of undetermined source (ESUS) with previous myocardial infarction or LV dysfunction (LV ejection fraction [LVEF]
Source: Stroke - August 28, 2017 Category: Neurology Authors: Junji Takasugi, Hiroshi Yamagami, Teruo Noguchi, Yoshiaki Morita, Tomotaka Tanaka, Yoshinori Okuno, Satoshi Yasuda, Kazunori Toyoda, Yasufumi Gon, Kenichi Todo, Manabu Sakaguchi, Kazuyuki Nagatsuka Tags: Diagnostic Testing, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Embolism, Thrombosis Original Contributions Source Type: research

Long-Delay Arterial Spin Labeling Provides More Accurate Cerebral Blood Flow Measurements in Moyamoya Patients Clinical Sciences
Background and Purpose—Arterial spin labeling (ASL) MRI is a promising, noninvasive technique to image cerebral blood flow (CBF) but is difficult to use in cerebrovascular patients with abnormal, long arterial transit times through collateral pathways. To be clinically adopted, ASL must first be optimized and validated against a reference standard in these challenging patient cases.Methods—We compared standard-delay ASL (post-label delay=2.025 seconds), multidelay ASL (post-label delay=0.7–3.0 seconds), and long-label long-delay ASL acquisitions (post-label delay=4.0 seconds) against simultaneous [15O]-positron emiss...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Audrey P. Fan, Jia Guo, Mohammad M. Khalighi, Praveen K. Gulaka, Bin Shen, Jun Hyung Park, Harsh Gandhi, Dawn Holley, Omar Rutledge, Prachi Singh, Tom Haywood, Gary K. Steinberg, Frederick T. Chin, Greg Zaharchuk Tags: Magnetic Resonance Imaging (MRI), Nuclear Cardiology and PET, Moyamoya Original Contributions Source Type: research

Vascular Tissue-Type Plasminogen Activator Promotes Intracranial Aneurysm Formation Basic Sciences
Conclusions—Altogether, this preclinical study demonstrates that the tPA present in the blood stream is a key player of the formation of IAs. Thus, tPA should be considered as a possible new target for the prevention of IAs formation and rupture.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Paul–Emile Labeyrie, Romain Goulay, Sara Martinez de Lizarrondo, Marie Hebert, Maxime Gauberti, Eric Maubert, Barbara Delaunay, Benȷamin Gory, Francesco Signorelli, Francis Turȷman, Emmanuel Touze, Patrick Courtheoux, Denis Vivien, Cyr Tags: Animal Models of Human Disease, Pathophysiology, Cerebral Aneurysm Original Contributions Source Type: research

Detecting Intracranial Vessel Wall Lesions With 7T-Magnetic Resonance Imaging Brief Report
Conclusions—Although overall intracranial vessel wall lesion burden and contrast enhancement were comparable between patients with recent posterior circulation ischemia and healthy controls, this study also revealed significant differences between the 2 groups, suggesting an association between posterior circulation lesion burden/enhancement and ischemic events.Clinical Trial Registration—URL: http://www.trialregister.nl. Unique identifier: NTR5688.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Anita A. Harteveld, Anja G. van der Kolk, H. Bart van der Worp, Nikki Dieleman, Jaco J.M. Zwanenburg, Peter R. Luijten, Jeroen Hendrikse Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA), Atherosclerosis Brief Reports Source Type: research

Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis Clinical Sciences
Background and Purpose—We assessed whether the presence, number, and distribution of cerebral microbleeds (CMBs) on pre-intravenous thrombolysis MRI scans of acute ischemic stroke patients are associated with an increased risk of intracerebral hemorrhage (ICH) or poor functional outcome.Methods—We performed an individual patient data meta-analysis, including prospective and retrospective studies of acute ischemic stroke treated with intravenous tissue-type plasminogen activator. Using multilevel mixed-effects logistic regression, we investigated associations of pre-treatment CMB presence, burden (1, 2–4, ≥5, and>10...
Source: Stroke - July 24, 2017 Category: Neurology Authors: Andreas Charidimou, Guillaume Turc, Catherine Oppenheim, Shenqiang Yan, Jan F. Scheitz, Hebun Erdur, Pascal P. Klinger–Gratz, Marwan El–Koussy, Wakoh Takahashi, Yusuke Moriya, Duncan Wilson, Chelsea S. Kidwell, Jeffrey L. Saver, Asma Sallem, S Tags: Magnetic Resonance Imaging (MRI), Prognosis, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Early Prediction of Delayed Ischemia and Functional Outcome in Acute Subarachnoid Hemorrhage Clinical Sciences
Background and Purpose—Diffusion tensor imaging (DTI) parameters are markers of cerebral lesion in some diseases. In patients with acute subarachnoid hemorrhage (SAH), we investigated whether DTI parameters measured at
Source: Stroke - July 24, 2017 Category: Neurology Authors: Isabel Fragata, Marta Alves, Ana Luisa Papoila, Ana Paiva Nunes, Patricia Ferreira, Nuno Canto–Moreira, Patricia Canhao Tags: Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage Original Contributions Source Type: research

Admission Brain Cortical Volume Clinical Sciences
Conclusions—Smaller cortical volumes in fronto-temporo-insular areas measured 24 to 72 hours post stroke are associated with cognitive vulnerability in the subacute stroke phase.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Sharmila Sagnier, Gwenaelle Catheline, Bixente Dilharreguy, Fanny Munsch, Antoine Bigourdan, Mathilde Poli, Sabrina Debruxelles, Stephane Olindo, Pauline Renou, Francois Rouanet, Vincent Dousset, Thomas Tourdias, Igor Sibon Tags: Magnetic Resonance Imaging (MRI), Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research

Age-Specific Sex Differences in Magnetic Resonance Imaging-Depicted Carotid Intraplaque Hemorrhage Clinical Sciences
We report age-specific sex differences in the presence of magnetic resonance imaging-depicted carotid IPH.Methods—Patients (n=1115) underwent magnetic resonance imaging for carotid IPH between 2005 and 2014. Low-grade carotid stenosis patients (n=906) without prior endarterectomy were eligible for this cross-sectional study.Results—Of the 906 patients included (mean age±SD in years, 66.98±15.15), 63 (6.95%) had carotid IPH. In men and women, carotid IPH was present in 11.43% (48 of 420) and 3.09% (15 of 486), respectively (P
Source: Stroke - July 24, 2017 Category: Neurology Authors: Navneet Singh, Alan R. Moody, Bowen Zhang, Isabella Kaminski, Kush Kapur, Stephanie Chiu, Pascal N. Tyrrell Tags: Pathophysiology, Vascular Biology, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Atherosclerosis Original Contributions Source Type: research

Noninvasive Assessment of Oxygen Extraction Fraction in Chronic Ischemia Using Quantitative Susceptibility Mapping at 7 Tesla Clinical Sciences
Conclusions—OEF ratios on QSM-OEF images at 7 Tesla showed a good correlation with those on PET-OEF images in patients with unilateral steno-occlusive internal carotid artery/middle cerebral artery lesions, suggesting that noninvasive OEF measurement by MRI can be a substitute for PET.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Ikuko Uwano, Kohsuke Kudo, Ryota Sato, Kuniaki Ogasawara, Hiroyuki Kameda, Jun-ichi Nomura, Futoshi Mori, Fumio Yamashita, Kenji Ito, Kunihiro Yoshioka, Makoto Sasaki Tags: Hemodynamics, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research