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Source: Stroke
Procedure: MRI Scan
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Total 526 results found since Jan 2013.
Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Scientific Statement
Two decades of epidemiological research shows that silent cerebrovascular disease is common and is associated with future risk for stroke and dementia. It is the most common incidental finding on brain scans. To summarize evidence on the diagnosis and management of silent cerebrovascular disease to prevent stroke, the Stroke Council of the American Heart Association convened a writing committee to evaluate existing evidence, to discuss clinical considerations, and to offer suggestions for future research on stroke prevention in patients with 3 cardinal manifestations of silent cerebrovascular disease: silent brain infarcts...
Source: Stroke - January 22, 2017 Category: Neurology Authors: Eric E. Smith, Gustavo Saposnik, Geert Jan Biessels, Fergus N. Doubal, Myriam Fornage, Philip B. Gorelick, Steven M. Greenberg, Randall T. Higashida, Scott E. Kasner, Sudha Seshadri Tags: Statements and Guidelines AHA/ASA Scientific Statement Source Type: research
Predictors and Clinical Impact of Incident Lacunes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Clinical Sciences
This study aimed to determine the predictors and clinical impact of such lesions in a large cohort of patients.Methods—Two hundred and six NOTCH3 mutation carriers (mean age, 49.5±10.6 years) were followed up over 3 years. Incident lacunes were identified using difference imaging from 3-dimensional T1 images. Clinical events and change in different clinical scores such as the Mattis Dementia Rating Scale, Modified Rankin Scale, Barthel index, and time to complete part A and part B of Trail Making Test were recorded. Associations were analyzed with multivariable logistic regression analysis and ANCOVA.Results—Over a me...
Source: Stroke - January 22, 2017 Category: Neurology Authors: Yifeng Ling, Francois De Guio, Marco Duering, Eric Jouvent, Dominique Herve, Ophelia Godin, Martin Dichgans, Hugues Chabriat Tags: Magnetic Resonance Imaging (MRI), CADASIL Original Contributions Source Type: research
Incidence, Locations, and Longitudinal Course of Cerebral Microbleeds in European Moyamoya Clinical Sciences
Background and Purpose—Cerebral microbleeds (cMBs) have previously been linked with especially high incidence in Asian patients with moyamoya together with high tendency to bleed. This, presumably, is characteristic of patients with moyamoya. Herein, we, therefore, investigate retrospectively the frequency, location, and longitudinal course of cMBs in a large German cohort.Methods—We included all patients with moyamoya who underwent standard magnetic resonance imaging, including T2*-weighted images, in our department between 1998 and 2015. Two independent readers evaluated magnetic resonance imaging scans to determine ...
Source: Stroke - January 22, 2017 Category: Neurology Authors: Holger Wenz, Ralf Wenz, Mate Maros, Gregory Ehrlich, Mansour Al–Zghloul, Christoph Groden, Alex Forster Tags: Imaging, Magnetic Resonance Imaging (MRI), Vascular Disease Original Contributions Source Type: research
NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke Study) Clinical Sciences
Conclusions—CEST is safe among unselected ischemic stroke patients with or without a visible occlusion on computed tomography angiography and with varying grades of clinical severity. There was, however, statistically no significant clinical effect of sonothrombolysis in this prematurely stopped trial.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01949961.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Aliona Nacu, Christopher E. Kvistad, Halvor Naess, Halvor Oygarden, Nicola Logallo, Jorg Assmus, Ulrike Waȷe–Andreassen, Kathinka D. Kurz, Gesche Neckelmann, Lars Thomassen Tags: Clinical Studies, Ischemia, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Is Unexplained Early Neurological Deterioration After Intravenous Thrombolysis Associated With Thrombus Extension? Clinical Sciences
Conclusions—In this study, unexplained END occurring after thrombolysis was independently associated with susceptibility vessel sign extension, suggesting in situ thrombus extension or re-embolization. These findings strengthen the need to further investigate early post-thrombolysis administration of antithrombotics to reduce the risk of this ominous clinical event.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Pierre Seners, Robert Hurford, Marie Tisserand, Guillaume Turc, Laurence Legrand, Olivier Naggara, Jean-Louis Mas, Catherine Oppenheim, Jean-Claude Baron Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research
Valproate Reduces Delayed Brain Injury in a Rat Model of Subarachnoid Hemorrhage Basic Sciences
Conclusions—In our rat SAH model, valproate treatment significantly reduced brain lesion growth after KCl application. Future studies are needed to confirm that this protective effect is based on SD inhibition.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Arend M. Hamming, Annette van der Toorn, Umesh S. Rudrapatna, Lisha Ma, Hine J.A. van Os, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Erik van Zwet, Katherine Poinsatte, Ann M. Stowe, Rick M. Dijkhuizen, Marieke J.H. Wermer Tags: Animal Models of Human Disease, Magnetic Resonance Imaging (MRI), Pharmacology, Cerebral Aneurysm, Neuroprotectants Original Contributions Source Type: research
Neuroimaging Biomarkers Predict Brain Structural Connectivity Change in a Mouse Model of Vascular Cognitive Impairment Basic Sciences
Conclusions—Overall, these findings suggest that, despite the autoregulatory abilities of the mouse brain to compensate for a sudden decrease in blood flow, there is evidence of change in the brain networks that can be used as neuroimaging biomarkers to predict outcome.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Philipp Boehm–Sturm, Martina Fuchtemeier, Marco Foddis, Susanne Mueller, Rebecca C. Trueman, Marietta Zille, Jan Leo Rinnenthal, Theodore Kypraios, Laurence Shaw, Ulrich Dirnagl, Tracy D. Farr Tags: Animal Models of Human Disease, Magnetic Resonance Imaging (MRI), Vascular Disease Original Contributions Source Type: research
Three-Dimensional Map of Neonatal Arterial Ischemic Stroke Distribution From Early Multimodal Brain Imaging Brief Report
Conclusions—This is the first report of an NAIS distribution map. Regions posterior to the central sulcus present increased vulnerability. Our findings suggest that motor areas are not as frequently affected as has been previously reported. By contrast, we find high NAIS vulnerability in functional areas related to language. The distribution of ischemic strokes in neonates seems to be different from that seen in adults.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Christian Stephan–Otto, Christian Nunez, Gemma Arca, Thais Agut, Alfredo Garcia–Alix Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Brief Reports Source Type: research
Infarct Pattern and Collateral Status in Adult Moyamoya Disease Clinical Sciences
Conclusions—In the studied population of adult MMD patients, embolic phenomenon played an important role in ischemic stroke. Therapeutic strategies against thromboembolism, as well as collateral enhancing strategies targeting improvement of hemodynamic status or increased washout of emboli, are warranted.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Dong Yeop Kim, Jeong Pyo Son, Je Young Yeon, Gyeong-Moon Kim, Jong-Soo Kim, Seung-Chyul Hong, Oh Young Bang Tags: Mechanisms, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Moyamoya Original Contributions Source Type: research
Prediction of Blood-Brain Barrier Disruption and Intracerebral Hemorrhagic Infarction Using Arterial Spin-Labeling Magnetic Resonance Imaging Clinical Sciences
Background and Purpose—Arterial spin-labeling magnetic resonance imaging is sensitive for detecting hyperemic lesions (HLs) in patients with acute ischemic stroke. We evaluated whether HLs could predict blood–brain barrier (BBB) disruption and hemorrhagic transformation (HT) in acute ischemic stroke patients.Methods—In a retrospective study, arterial spin-labeling was performed within 6 hours of symptom onset before revascularization treatment in 25 patients with anterior circulation large vessel occlusion on baseline magnetic resonance angiography. All patients underwent angiographic procedures intended for endovasc...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Takeya Niibo, Hajime Ohta, Shirou Miyata, Ichiro Ikushima, Kazuchika Yonenaga, Hideo Takeshima Tags: Imaging, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Quantification of Serial Cerebral Blood Flow in Acute Stroke Using Arterial Spin Labeling Clinical Sciences
Background and Purpose—Perfusion-weighted imaging is used to select patients with acute ischemic stroke for intervention, but knowledge of cerebral perfusion can also inform the understanding of ischemic injury. Arterial spin labeling allows repeated measurement of absolute cerebral blood flow (CBF) without the need for exogenous contrast. The aim of this study was to explore the relationship between dynamic CBF and tissue outcome in the month after stroke onset.Methods—Patients with nonlacunar ischemic stroke underwent ≤5 repeated magnetic resonance imaging scans at presentation, 2 hours, 1 day, 1 week, and 1 month....
Source: Stroke - December 22, 2016 Category: Neurology Authors: George W.J. Harston, Thomas W. Okell, Fintan Sheerin, Ursula Schulz, Phil Mathieson, Ian Reckless, Kunal Shah, Gary A. Ford, Michael A. Chappell, Peter Jezzard, James Kennedy Tags: Ischemic Stroke Original Contributions Source Type: research
Frequency and Predictors of Dysphagia in Patients With Recent Small Subcortical Infarcts Brief Report
Background and Purpose—Detailed data on the occurrence of swallowing dysfunction in patients with recent small subcortical infarcts (RSSI) in the context of cerebral small vessel disease are lacking. This prompted us to assess the frequency of and risk factors for dysphagia in RSSI patients.Methods—We identified all inpatients with magnetic resonance imaging–confirmed RSSI between January 2008 and February 2013. Demographic and clinical data were extracted from our stroke database, and magnetic resonance imaging scans were reviewed for morphological changes. Dysphagia was determined according to the Gugging Swallowin...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Simon Fandler, Thomas Gattringer, Sebastian Eppinger, Kathrin Doppelhofer, Daniela Pinter, Kurt Niederkorn, Christian Enzinger, Joanna M. Wardlaw, Franz Fazekas Tags: Magnetic Resonance Imaging (MRI), Complications, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research
Magnetic Resonance Imaging and Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Topical Reviews
Source: Stroke - December 22, 2016 Category: Neurology Authors: Lisa A. van der Kleij, Jill B. De Vis, Jean-Marc Olivot, Lionel Calviere, Christophe Cognard, Nicolaas P.A. Zuithoff, Gabriel J.E. Rinkel, Jeroen Hendrikse, Mervyn D.I. Vergouwen Tags: Imaging, Magnetic Resonance Imaging (MRI), Meta Analysis, Cerebral Aneurysm, Cerebrovascular Disease/Stroke Topical Review Source Type: research
Insulin Resistance Is a Risk Factor for Silent Lacunar Infarction Clinical Sciences
This study aims to investigate the association between insulin resistance (IR) and silent lacunar infarction (SLI) in healthy adults.Methods—We recruited 2326 healthy Korean adults who took health checkups, including a brain magnetic resonance imaging. SLI was defined as an infarction measuring 0.3 to 1.5 cm in diameter that was localized in the territory of perforating branches of cerebral arteries, as seen in the brain magnetic resonance imaging. The homeostasis model assessment–estimated insulin resistance index was used for IR estimation, and the cutoff value for its diagnosis for Koreans was 2.56.Results—The mea...
Source: Stroke - November 27, 2016 Category: Neurology Authors: Ji Eun Lee, Dong Wook Shin, Jae Moon Yun, Sang Hyuck Kim, You-Seon Nam, BeLong Cho, Jae-Sung Lim, Han-Yeong Jeong, Hyung-Min Kwon, Jin-Ho Park Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial) Clinical Sciences
Conclusions—We found an association between right insular involvement and higher odds of death and worse functional outcome. The difference between right- and left-sided insular lesions on outcomes seemed to be most evident for mild/moderate strokes.Clinical Trial Registration—URL: http://www.isrctn.com. Unique identifier: ISRCTN25765518.
Source: Stroke - November 27, 2016 Category: Neurology Authors: Luciano A. Sposato, Geoffrey Cohen, Joanna M. Wardlaw, Peter Sandercock, Richard I. Lindley, Vladimir Hachinski, on behalf of the IST-3 Expert Reading Panel and the IST-3 Collaborative Group Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research
