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Source: Stroke
Procedure: MRI Scan

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Total 526 results found since Jan 2013.

Cerebral Microbleeds in Murine Amyloid Angiopathy Basic Sciences
Conclusions—Anticoagulation with warfarin or dabigatran for 3 to 4 months does not promote the formation of CMBs in aged APP23 mice. Nevertheless, warfarin but not dabigatran is associated with a higher risk of extensive intracerebral hemorrhage, suggesting that this model may allow preclinical safety evaluation of antithrombotic therapies.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Marilena Marinescu, Li Sun, Marc Fatar, Andreas Neubauer, Lothar Schad, Joanne van Ryn, Lorenz Lehmann, Roland Veltkamp Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies Original Contributions Source Type: research

Ischemic Amnesia Brief Report
Conclusions—Amnesia as the main symptom of acute ischemic cerebral events is rare, mostly transient, and easily mistaken for TGA. Although clinical clues are often present, the threshold for performing diffusion-weighted imaging in acute amnesia should be low.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Patrik Michel, Valerie Beaud, Ashraf Eskandari, Philippe Maeder, Jean–Francois Demonet, Elissavet Eskioglou Tags: Imaging, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Cognitive Impairment, Ischemic Stroke Brief Reports Source Type: research

Predicting Progression of Intracranial Arteriopathies in Childhood Stroke With Vessel Wall Imaging Brief Report
Conclusions—Our case series demonstrates the potential benefit of VWI in children with stroke because it may identify patients who will have progressive arterial disease.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Nicholas V. Stence, Lisa L. Pabst, Amanda L. Hollatz, David M. Mirsky, Paco S. Herson, Sharon Poisson, Richard J. Traystman, Timothy J. Bernard Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Regional Pediatric Acute Stroke Protocol Brief Report
Conclusions—Hyperacute recanalization treatment in pediatric stroke, relying on common protocols and adult/pediatric ward collaboration, is feasible. Larger systematic case collection is encouraged.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Laurence Tabone, Nicolas Mediamolle, Celine Bellesme, Fabrice Lesage, David Grevent, Augustin Ozanne, Olivier Naggara, Beatrice Husson, Isabelle Desguerre, Catherine Lamy, Christian Denier, Manoelle Kossorotoff Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate Brief Report
Conclusions—The CSF actively penetrates within the brain parenchyma in the gyrencephalic brain, as described for the glymphatic system in rodent. This parenchymal CSF circulation is severely impaired by SAH.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Romain Goulay, Julien Flament, Maxime Gauberti, Michael Naveau, Nolwenn Pasquet, Clement Gakuba, Evelyne Emery, Philippe Hantraye, Denis Vivien, Romina Aron-Badin, Thomas Gaberel Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies Brief Reports Source Type: research

Letter by Stanley et al Regarding Article, “Primary Angiitis of the Central Nervous System Magnetic Resonance Imaging Spectrum of Parenchymal, Meningeal, and Vascular Lesions at Baseline” Letter to the Editor
Source: Stroke - June 26, 2017 Category: Neurology Authors: Emma Stanley, Sean Murphy, Eoin Kavanagh Tags: Diagnostic Testing, Magnetic Resonance Imaging (MRI) Letters to the Editor Source Type: research

Response by Boulouis et al to Letter Regarding Article, “Primary Angiitis of the Central Nervous System: Magnetic Resonance Imaging Spectrum of Parenchymal, Meningeal, and Vascular Lesions at Baseline” Letter to the Editor
Source: Stroke - June 26, 2017 Category: Neurology Authors: Gregoire Boulouis, Hubert de Boysson, Olivier Naggara Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Letters to the Editor Source Type: research

Effect of Long-Term Vascular Care on Progression of Cerebrovascular Lesions Clinical Sciences
Conclusions—Nurse-led vascular care in hypertensive community-dwelling older persons did not diminish WMH accumulation over 3 years. However, our results do suggest this type of intervention could be effective in persons with high WMH volumes. There was no effect on lacunar infarcts incidence but numbers were low.Clinical Trial Information—URL: http://www.isrctn.com/ISRCTN29711771. Unique identifier: ISRCTN29711771.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Jan Willem van Dalen, Eric P. Moll van Charante, Matthan W.A. Caan, Philip Scheltens, Charles B.L.M. Majoie, Aart J. Nederveen, Willem A. van Gool, Edo Richard Tags: Aging, Primary Prevention, Hypertension, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Multiparametric Model for Penumbral Flow Prediction in Acute Stroke Clinical Sciences
In this study, we established a multiparametric perfusion imaging model and cross-validated it using positron emission tomography perfusion for detection of penumbral flow.Methods—In a retrospective analysis of 17 subacute stroke patients with consecutive magnetic resonance imaging and H2O15 positron emission tomography scans, perfusion maps of cerebral blood flow, cerebral blood volume, mean transit time, time-to-maximum, and time-to-peak were constructed and combined using a generalized linear model (GLM). Both the GLM maps and the single perfusion maps alone were cross-validated with positron emission tomography-cereb...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Michelle Livne, Tabea Kossen, Vince I. Madai, Olivier Zaro-Weber, Walter Moeller-Hartmann, Kim Mouridsen, Wolf-Dieter Heiss, Jan Sobesky Tags: Imaging, Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research

Predicting Domain-Specific Health-Related Quality of Life Using Acute Infarct Volume Clinical Sciences
Background and Purpose—Limited data exist on the relationship between acute infarct volume and health-related quality of life (HRQOL) measures after ischemic stroke. We evaluated whether acute infarct volume predicts domain-specific Neuro-Quality of Life scores at 3 months after stroke.Methods—Between 2012 and 2014, we prospectively enrolled consecutive patients with ischemic stroke and calculated infarct volume. Outcome scores at 3 months included modified Rankin Scale and Neuro-Quality of Life T scores. We evaluated whether volume organized by quartiles predicted modified Rankin Scale and HRQOL scores at 3 months usi...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Chen Lin, Jungwha Lee, Neil Chatterjee, Carlos Corado, Timothy Carroll, Andrew Naidech, Shyam Prabhakaran Tags: Magnetic Resonance Imaging (MRI), Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Exacerbation of Thromboinflammation by Hyperglycemia Precipitates Cerebral Infarct Growth and Hemorrhagic Transformation Basic Sciences
Conclusions—We show that hyperglycemia primes the thromboinflammatory cascade, thus, amplifying middle cerebral artery occlusion–induced DMT. DMT exacerbation in hyperglycemic rats impaired reperfusion and precipitated neurovascular damage, blood–brain barrier disruption, and hemorrhagic transformation. Our results designate DMT as a possible target for reduction of the deleterious impact of hyperglycemia in acute ischemic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Jean–Philippe Desilles, Varouna Syvannarath, Veronique Ollivier, Clement Journe, Sandrine Delbosc, Celina Ducroux, William Boisseau, Liliane Louedec, Lucas Di Meglio, Stephane Loyau, Martine Jandrot–Perrus, Louis Potier, Jean–Baptiste Mi Tags: Biomarkers, Inflammation, Pathophysiology, Blood-Brain Barrier, Ischemic Stroke Original Contributions Source Type: research

Sustained Neurological Recovery After Stroke in Aged Rats Treated With a Novel Prostacyclin Analog Basic Sciences
Conclusions—Our data suggest that targeting the IP receptor with MRE-269 is a novel strategy to reduce cerebral ischemia injury and promote long-term neurological recovery in ischemic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Changjun Yang, Kelly M. DeMars, Jon C. Alexander, Marcelo Febo, Eduardo Candelario-Jalil Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Long-Term Exposure to Ambient Air Pollution and Subclinical Cerebrovascular Disease in NOMAS (the Northern Manhattan Study) Brief Report
Conclusions—We found no evidence that long-term exposure to ambient air pollution is independently associated with subclinical cerebrovascular disease in an urban population-based cohort.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Erin R. Kulick, Gregory A. Wellenius, Joel D. Kaufman, Janet T. DeRosa, Patrick L. Kinney, Ying Kuen Cheung, Clinton B. Wright, Ralph L. Sacco, Mitchell S. Elkind Tags: Epidemiology, Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Overestimation of Susceptibility Vessel Sign Brief Report
Conclusions—The overestimation ratio of SVS can predict cardiogenic embolism, with both high sensitivity and specificity, which can be helpful for the management of acute ischemic stroke patients in hyperacute stage.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Ruiting Zhang, Ying Zhou, Chang Liu, Meixia Zhang, Shenqiang Yan, David S. Liebeskind, Min Lou Tags: Clinical Studies, Etiology, Magnetic Resonance Imaging (MRI), Ischemic Stroke Brief Reports Source Type: research

Prevalence of Developmental Venous Anomalies Increases With Age Brief Report
Background and Purpose—To test the hypothesis that developmental venous anomalies (DVAs) may develop in the postnatal period, we studied the age-related prevalence of DVAs on contrast-enhanced magnetic resonance imaging.Methods—Reports from a consecutive series of head magnetic resonance images with intravenous contrast performed over a 2-year period at our institution were reviewed. Studies reporting the presence of a DVA were retrieved and reviewed by a neuroradiologist. Patients were divided into 4 age groups: (1)
Source: Stroke - June 26, 2017 Category: Neurology Authors: Waleed Brinjikji, Ali El-Rida El-Masri, John T. Wald, Giuseppe Lanzino Tags: Cerebrovascular Malformations, Vascular Disease Brief Reports Source Type: research