Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable [Clinical Sciences]

Conclusions—We provide evidence for important genetic contribution to dPVS burden in older community-dwelling people, some of which may be shared with WMHV. Differential heritability patterns for dPVS in white matter and basal ganglia suggest at least partly distinct underlying biological processes.

Source: Stroke - January 22, 2018 Category: Neurology Authors: Marie–Gabrielle Duperron, Christophe Tzourio, Muralidharan Sargurupremraȷ, Bernard Mazoyer, Aicha Soumare, Sabrina Schilling, Philippe Amouyel, Ganesh Chauhan, Yi–Cheng Zhu, Stephanie Debette Tags: Aging, Epidemiology, Genetics, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research