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Total 276 results found since Jan 2013.

Trends in Carotid Revascularization Procedures
To the Editor In a study of Medicare beneficiaries during 1999-2014, 30-day ischemic stroke or death rates after carotid endarterectomy improved (from 4.4% in 1999-2000 to 3.1% in 2013-2014), as did all-cause mortality (from 1.6% to 1.1%). In contrast, 30-day ischemic stroke or death rates after carotid artery stenting did not differ between the beginning and the end of the study period (7.0% in 1999-2000 and 7.0% in 2013-2014) and neither did all-cause mortality (4.7% in 1999-2000 and 4.8% in 2013-2014). Importantly, 30-day ischemic stroke or death rates after carotid artery stenting were higher than those recommended by ...
Source: JAMA - January 16, 2018 Category: General Medicine Source Type: research

Trends in Carotid Revascularization Procedures —Reply
In Reply Dr Hussain and colleagues point out interesting comparisons in carotid revascularization trends in Ontario, Canada, and in the US Medicare population, including similar 30-day stroke or death outcomes after carotid endarterectomy and stenting. We agree that differing reimbursement policies in the United States and Canada may account for differing patterns of carotid stenting after 2006. A noted difference is the lower receipt of procedures among symptomatic patients in the United States vs Ontario. However, such variation is expected because the approach to asymptomatic treatment has been shown to vary among Western countries.
Source: JAMA - January 16, 2018 Category: General Medicine Source Type: research

Heat Stroke
This JAMA Patient Page describes heat stroke, its prevention, and its treatment.
Source: JAMA - December 26, 2017 Category: General Medicine Source Type: research

Incorrect Statistical Measures and Typographical Errors
This article was corrected online.
Source: JAMA - November 14, 2017 Category: General Medicine Source Type: research

Stroke Death Rate Plateaus
The steady, nearly half-century decline in the US death rate from stroke appears to have stopped in the last few years, according to arecent report.
Source: JAMA - November 14, 2017 Category: General Medicine Source Type: research

Oxygen Supplementation After Acute Stroke
Three months after acute stroke, this randomized clinical trial compares rates of death and disability among adult patients receiving continuous or nocturnal low-dose oxygen supplementation or control intervention (oxygen only if clinically indicated.
Source: JAMA - September 26, 2017 Category: General Medicine Source Type: research

Antiphospholipid Antibodies
A 39-year-old man with a history of ischemic stroke presented with right calf swelling and shortness of breath and was diagnosed with pulmonary embolism by CTPA. Testing 2 days later showed elevated titers of anticardiolipin and anti –β2 glycoprotein I antibodies and negative lupus anticoagulant screening assays. How would you interpret these results?
Source: JAMA - September 12, 2017 Category: General Medicine Source Type: research

Exosuit for Stroke Rehabilitation
Researchers at Harvard University and Boston University have developed a lightweight, soft robotic exosuit that improves gait in patients who have experienced a stroke.
Source: JAMA - September 12, 2017 Category: General Medicine Source Type: research

PCSK9 Inhibitors and the Choice Between Innovation, Efficiency, and Affordability
Cardiovascular medicine is struggling with the new proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor drugs for lowering low-density lipoprotein cholesterol (LDL), not primarily because of efficacy concerns or safety issues, but because the price of these new agents exceeds $14  000 a year. While clinicians are seeking to understand how best to exploit the potential for enhanced protection these drugs may provide to patients at risk of atherosclerotic complications (such as myocardial infarction and stroke), payers are focused on constraining the use of these medications , recognizing that the pool of candid...
Source: JAMA - August 22, 2017 Category: General Medicine Source Type: research

A Song of Hope
I will playthe last fugue of my lifeon the melting ice and rising seasas they stroke their furythrough organs and bones,on the ivory keys of an elephant ’s tuskand curl through a pangolin’s scales.They will sound in the fossil cochlea of a whale,its vertebra holding a shelletched in a lost language by expired hands.And the trees who still stand will protect useven as sea turtles drownand the ears of dolphins bleed from the noise.But the birds wh o still fly will sing me to restand the chords they still playwill be heard.
Source: JAMA - August 15, 2017 Category: General Medicine Source Type: research

Thrombectomy Using Contact Aspiration vs Stent Retriever in Ischemic Stroke
This randomized trial compares the effects of thrombectomy with a contact aspiration vs a stent retriever technique on successful endovascular revascularization in patients with acute ischemic stroke.
Source: JAMA - August 1, 2017 Category: General Medicine Source Type: research

Does Obstructive Sleep Apnea Treatment Reduce Cardiovascular Risk? It Is Far Too Soon to Say
The association of obstructive sleep apnea (OSA) with vascular disease and mortality was reported in clinical case series almost 3 decades ago and has since been confirmed in numerous prospective observational studies involving both sleep clinic patients and community-based cohorts. Physiological studies in animals and humans have suggested likely mechanisms whereby the intermittent hypercapnic hypoxemia and recurrent arousal from sleep that characterize OSA might cause vascular disease. The most strongly implicated mechanism is increased sympathetic nervous system activity, with considerable evidence as well for impaired ...
Source: JAMA - July 11, 2017 Category: General Medicine Source Type: research

Incorrect Funder
This article wa s corrected online.
Source: JAMA - May 9, 2017 Category: General Medicine Source Type: research

Misspelling of Author Name
This article was corrected online.
Source: JAMA - May 9, 2017 Category: General Medicine Source Type: research

Spider Venom Peptide May Protect Neurons After Stroke
A disulfide-rich spider venom peptide reduced brain damage in rats when given up to 8 hours after a stroke, according to a recentstudy published in theProceedings of the National Academy of Sciences.
Source: JAMA - May 2, 2017 Category: Journals (General) Source Type: research