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Source: JAMA
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Total 276 results found since Jan 2013.
A Recent Study Linked Diet Soda With Stroke —But Is It Correlation or Causation?
This Medical News article is an interview with Yasmin Mossavar-Rahmani, PhD, RD, who studied the association of artificially sweetened beverages with cardiovascular disease and mortality in women.
Source: JAMA - April 23, 2019 Category: General Medicine Source Type: research
Cerebral Intraparenchymal Hemorrhage
This narrative review summarizes the pathophysiology, presentation, and management of patients with intraparenchymal hemorrhagic stroke, and approaches to poststroke rehabilitation, risk factor management, and anticoagulation.
Source: JAMA - April 2, 2019 Category: General Medicine Source Type: research
Association of Aspirin Use for Primary Prevention of CVD With Cardiovascular Events and Bleeding
This meta-analysis estimates the association between use of aspirin for primary prevention of cardiovascular disease and the rate of cardiovascular mortality, nonfatal myocardial infarction, nonfatal stroke, and bleeding.
Source: JAMA - January 22, 2019 Category: General Medicine Source Type: research
Clinical Considerations for Aspirin Use for Primary Prevention in 2019
Reducing platelet activity with aspirin and other antiplatelet agents is an important factor in the prevention and management of atherothrombotic vascular events. For this indication, aspirin has both beneficial and potentially harmful effects; it can diminish or reverse thrombus formation (eg, in the setting of acute myocardial infarction or stroke), but it also increases the risk of bleeding.
Source: JAMA - January 22, 2019 Category: General Medicine Source Type: research
Matched-Sibling Stem Cell Transplantation and Stroke in Children With SCA
Stroke is one of the most devastating complications of sickle cell anemia (SCA), and risk of stroke starts very early in life. Before screening techniques were available, 11% of children with homozygous SCA had ischemic stroke by their 20th birthday. Although most children with SCA will have neurologic recovery after stroke, approximately one-third will have long-term neurologic sequelae, including motor impairment. Moreover, children with SCA who have had a stroke often have neurocognitive impairment and difficulties with academic performance.
Source: JAMA - January 22, 2019 Category: General Medicine Source Type: research
Hypertension —A Public Health Challenge of Global Proportions
This issue ofJAMA, from illustrated cover to in-depth content, is dedicated to hypertension, a worldwide problem of enormous consequence. High blood pressure affects more than 1 billion people worldwide, and that number is increasing. Untreated or uncontrolled, hypertension is the single largest contributor to cardiovascular disease, causing stroke, heart failure, coronary artery disease, and kidney disease, and also is a major contributor to kidney disease. Progress over the last several decades has led to increased understanding of the relationship between blood pressure and health outcomes and to the development of mult...
Source: JAMA - November 6, 2018 Category: General Medicine Source Type: research
Association Between Young Adult Hypertension and Cardiovascular Events in Middle Age
This cohort study investigates associations between blood pressure classifications defined by the 2017 ACC/AHA guidelines in adults younger than 40 years and long-term CVD events including myocardial infarction, heart failure, and stroke.
Source: JAMA - November 6, 2018 Category: General Medicine Source Type: research
Benefits May Persist After Antihypertensive and Statin Treatment
Patients with hypertension may benefit from antihypertensive treatment with a calcium channel blocker and a lipid-lowering statin years after taking the medications, reported a long-term follow-upstudy in theLancet. Patients who received amlodipine-based antihypertensive treatment had fewer stroke deaths —independent of blood pressure levels—and patients taking lipid-lowering atorvastatin had fewer cardiovascular deaths.
Source: JAMA - October 23, 2018 Category: General Medicine Source Type: research
Left Atrial Appendage Occlusion and Surgical Ablation for AF During Cardiac Surgery
To the Editor Dr Yao and colleagues identified an association between left atrial appendage occlusion (LAAO) and reduced risk of stroke and all-cause mortality after cardiac surgery in a large insurance database (75 782 patients). There are limitations of the study that require careful consideration.
Source: JAMA - October 16, 2018 Category: General Medicine Source Type: research
Left Atrial Appendage Occlusion and Surgical Ablation for AF During Cardiac Surgery —Reply
In Reply Dr Coyan and colleagues point out that LAAO and surgical ablation of AF are often performed together, and they raise a question whether surgical ablation, rather than LAAO, was responsible for the association with reduced risks of stroke and mortality in our study. We believe that surgical AF ablation is unlikely to have influenced our findings.
Source: JAMA - October 16, 2018 Category: General Medicine Source Type: research
Cardiovascular Disease in India
Ischemic heart disease deaths are rising in India, particularly in rural areas and among young adults, while deaths from stroke have dropped in most parts of the country, according to a study inThe Lancet Global Health.
Source: JAMA - September 18, 2018 Category: General Medicine Source Type: research
Clinical and Imaging Characteristics Associated With Thrombus Recanalization in Ischemic Stroke
This cohort study examines baseline clinical and biochemical variables, intracranial thrombus characteristics, and stroke workflow interval times associated with clot recanalization among patients with ischemic stroke treated with intravenous alteplase.
Source: JAMA - September 11, 2018 Category: General Medicine Source Type: research
Electrocardiographic Monitoring for Prevention of AF-Associated Cardioembolic Stroke
Screening appropriate populations for atrial fibrillation has become an important clinical question, because cardioembolic stroke may be the first clinical manifestation of atrial fibrillation. In this issue ofJAMA, the US Preventive Services Task Force (USPSTF) provides its Recommendation Statement on screening for atrial fibrillation with electrocardiography (ECG), based on a detailed review of the evidence. For a substantial number of patients, atrial fibrillation may first be diagnosed concurrent with the stroke or in follow-up. Given the known association of atrial fibrillation with stroke and that anticoagulation can...
Source: JAMA - August 7, 2018 Category: General Medicine Source Type: research
Intravenous Alteplase for Mild Nondisabling Acute Ischemic Stroke
Treatment of patients with stroke has changed substantially during the past 25 years. In 1995, the NINDS rt-PA trial showed among selected patients with acute ischemic stroke who were treated with intravenous alteplase within 3 hours of known stroke onset or last known well time had reduced disability at 3 months. In 2008, the ECASS III trial demonstrated benefit of intravenous alteplase among selected patients treated up to 4.5 hours after known stroke onset or last known well time. Benefit from alteplase treatment occurred despite higher rates of symptomatic intracranial hemorrhage compared with placebo (6.4% vs 0.6% in ...
Source: JAMA - July 10, 2018 Category: General Medicine Source Type: research
Ankle Brachial Index Screening and Improving Peripheral Artery Disease Detection and Outcomes
Lower extremity peripheral artery disease (PAD) affects an estimated 8.5 million adults in the United States and 202 million adults worldwide. PAD consists of atherosclerosis of the lower extremity arteries, resulting in inadequate oxygen supply to lower extremity muscles during walking activity. People with PAD typically walk only 1 to 3 blocks before having to stop and rest because of ischemic leg symptoms. PAD is also a marker for the presence of atherosclerotic disease in the coronary and cerebrovascular arteries. Consistent with this phenomenon, people with PAD have higher rates of acute coronary events, ischemic stro...
Source: JAMA - July 10, 2018 Category: General Medicine Source Type: research
