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Specialty: Neurology
Source: Neurological Research

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Total 488 results found since Jan 2013.

Ligustilide provides neuroprotection by promoting angiogenesis after cerebral ischemia.
CONCLUSION: LGSL promoted focal angiogenesis and attenuated ischemia-induced brain injury, suggesting that LGSL is a potential agent that improves angiogenesis and promotes recovery from ischemic stroke. PMID: 32584207 [PubMed - as supplied by publisher]
Source: Neurological Research - June 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Impact of post-stroke disability and disability-perception on health-related quality of life of stroke survivors: the moderating effect of disability-severity.
CONCLUSION: Significant disability exists among stroke survivors and impaired their HRQoL while disability-severity moderating the effect. More stroke survivors have positive attitude towards their disability and impact positively on their physical health. PMID: 32573376 [PubMed - as supplied by publisher]
Source: Neurological Research - June 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Intracranial collaterals and arterial wall features in severe symptomatic vertebrobasilar stenosis.
CONCLUSION: Intracranial good collateral of posterior circulation may be associated with lower risk of arterial positive remodeling and culprit plaque diffuse distribution, plaque enhancement in patients with severe sIVBAS. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT02705599. PMID: 32573371 [PubMed - as supplied by publisher]
Source: Neurological Research - June 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The effect of cyclosporin a on ischemia-reperfusion damage in a mouse model of ischemic stroke.
DISCUSSION: CsA showed potential as a neuroprotective drug for the treatment of ischemic stroke patients; besides interfering with the typical NF-κB signaling pathway, the Akt pathway may also be involved in the effects of CsA. PMID: 32529968 [PubMed - as supplied by publisher]
Source: Neurological Research - June 14, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Association between mitral regurgitation and clinical outcome after endovascular thrombectomy in stroke patients.
CONCLUSIONS: Significant MR might prevent the clinical recovery of AF patients. PMID: 32497466 [PubMed - as supplied by publisher]
Source: Neurological Research - June 5, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Population-based stroke surveillance using big data: state-wide epidemiological trends in admissions and mortality in New South Wales, Australia.
DISCUSSION: Improved prevention may have underpinned declining intracerebral haemorrhage rates while survival gains suggest that innovations in care are being successfully translated. Mortality in patients surviving the acute period is unchanged and may be increasing for subarachnoid haemorrhage warranting investment in post-discharge care and secondary prevention. PMID: 32449879 [PubMed - as supplied by publisher]
Source: Neurological Research - May 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Factors associated with medication persistence among ischemic stroke patients: a systematic review.
Conclusions: Stroke patients' medication persistence decreases over time, and persistence on antiplatelets, anticoagulants, and statin was poor. Several factors were associated with medication persistence, and these factors should be considered in future secondary preventative strategies. PMID: 32321382 [PubMed - as supplied by publisher]
Source: Neurological Research - April 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Evaluation of intracranial and extracranial atherosclerotic lesions in patients with symptomatic coronary artery disease.
Conclusions: The prevalence of ECAD, ICAD and EICAD is high in patients with CAD, and the presence of these conditions is positively correlated with the extent and degree of CAD. Evaluations of ECAD and ICAD should be highly recommended for CAD patients to reduce the future risk of cardiovascular diseases. PMID: 32284016 [PubMed - as supplied by publisher]
Source: Neurological Research - April 16, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Assessment of the manifestations of atrial fibrillation in patients with acute cerebral stroke - a single-center study based on 998 patients.
Discussion: The above data should prompt neurologists, cardiologists and family doctors to try to detect AF as a risk factor for ischemic stroke which worsens patient prognosis, prolongs hospital stay and contributes to increase in mortality, especially when more effective drug treatment is currently possible. PMID: 32241245 [PubMed - as supplied by publisher]
Source: Neurological Research - April 5, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Human urinary kallidinogenase in treating acute ischemic stroke patients: analyses of pooled data from a randomized double-blind placebo-controlled phase IIb and phase III clinical trial.
Conclusion: HUK is safe and provides potential clinical benefits as a treatment for acute ischemic stroke. Further large post-marketing observational studies are needed. PMID: 32138624 [PubMed - as supplied by publisher]
Source: Neurological Research - March 7, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Statin effects on post-stroke epilepsy and mortality - Taiwan population-based study.
Conclusion: Statins have a modest but non-significant effect in preventing post-apoplectic epilepsy in Taiwan. Statins decrease post-stroke mortality only in men. Further studies are needed to depict their exact roles in these issues. PMID: 32122287 [PubMed - as supplied by publisher]
Source: Neurological Research - March 4, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Inducing ketogenesis via an enteral formulation in patients with acute brain injury:a phase II study.
Conclusion: In patients with acute brain injury, an enterally administered ketogenic formulation increased plasma ketone concentrations, was well tolerated, did not impact on cerebral hemodynamics and can be safely administered.Clinical trial registered at the Australian New Zealand Clinical Trials Registry (ACTRN12616000332426)Abbreviations: BHB: betahydroxybutyrate; AcAc: acetoacetate; ABI: acute brain injury; TBI: traumatic brain injury; CSF: cerebrospinal fluid; SAH: subarachnoid injury; CVA: cerebrovascular accidents; ICP: intracranial pressure; CPP: cerebral perfusion pressure; ICU: intensive care unit; EVD: external...
Source: Neurological Research - February 28, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The effect of intravenous ginkgolide on clinical improvement of patients with acute ischemic stroke.
Conclusion: Intravenous ginkgolide may improve the outcome of acute ischemic stroke. Differences in effect between pre-marketing and post-marketing studies may be associated with gender, time of onset to enrollment and severity of stroke. PMID: 32048567 [PubMed - as supplied by publisher]
Source: Neurological Research - February 13, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Flexors activity of affected upper extremity in stroke patients during different standing conditions and their relationships with clinical scales: a cross-sectional study.
Conclusions: The contraction rates of elbowflexor in the affected side increase with the difficulty in different standing postures,and it may be a good index to reflect the changes of muscle tone in postural control. PMID: 32048562 [PubMed - as supplied by publisher]
Source: Neurological Research - February 13, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Low density lipoprotein cholesterol values and outcome of stroke patients: influence of previous aspirin therapy.
Conclusion: A worse outcome was seen in stroke patients with normal levels of LDLC, but this finding was restricted to patients not under previous aspirin therapy. PMID: 32024449 [PubMed - as supplied by publisher]
Source: Neurological Research - February 8, 2020 Category: Neurology Tags: Neurol Res Source Type: research