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Specialty: Neurology
Source: JAMA Neurology

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Total 364 results found since Jan 2013.

Ischemic Stroke Incidence Trends After Transient Ischemic Attack
This systematic review and meta-analysis calculates the pooled event rate for ischemic stroke within 2, 7, 30, and 90 days of a transient ischemic attack and compares this incidence among patients recruited before 1999, from 1999 to 2007, and after 2007.
Source: JAMA Neurology - October 12, 2020 Category: Neurology Source Type: research

Remote Ischemic Perconditioning for the Treatment of Acute Ischemic Stroke —Reply
In Reply We thank Zhao et al for the interest in our randomized clinical trial. We agree that it is of interest to evaluate remote ischemic perconditioning specifically in patients with acute ischemic stroke and mismatch. We did not target these patients exclusively, because when the Remote Ischemic Conditioning in Acute Brain Infarction (RESCUE BRAIN) was designed in 2012, there was no proof of the efficacy of this approach; the DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention with Trevo (DAWN) and Endovascular Therapy Following Imaging Evaluati...
Source: JAMA Neurology - September 28, 2020 Category: Neurology Source Type: research

Remote Ischemic Perconditioning for the Treatment of Acute Ischemic Stroke
To the Editor We read with interest the article by Pico et al, who reported the results of a randomized clinical trial to determine whether remote ischemic perconditioning can reduce brain infarction volume growth in patients with acute ischemic stroke. In the study, treatment with remote ischemic perconditioning had no significant effect on brain infarction volume growth at 24 hours after symptom onset. Two main hypotheses were proposed for the neutral results: remote ischemic perconditioning may not have any beneficial effect, or this trial mainly recruited patients who had received reperfusion therapies. However, we con...
Source: JAMA Neurology - September 28, 2020 Category: Neurology Source Type: research

Reperfusion Therapy for In-Hospital Ischemic Stroke in the Endovascular Therapy Era
This cohort study uses a large US national registry to assess temporal trends from 2008 to 2018 in the use of intravenous and endovascular reperfusion therapies, process measures of quality, and association between functional outcomes and key patient characteristics, comorbidities, and treatments of in-hospital vs out-of-hospital stroke onset.
Source: JAMA Neurology - September 21, 2020 Category: Neurology Source Type: research

In-Hospital Acute Strokes —Opportunities to Optimize Care and Improve Outcomes
Stroke is a well-known complication of acute medical or surgical illnesses. Prior work has shown that patients with stroke occurring in the hospital are more likely to encounter delays in diagnosis, have gaps in care, and experience worse outcomes compared with patients with stroke occurring out of the hospital. Delay in the recognition of symptoms of stroke is particularly relevant for extremely short-term revascularization therapies, which was previously limited to a relatively narrow time window for treatment with intravenous thrombolysis. Patients with in-hospital stroke may be more likely than patients with community-...
Source: JAMA Neurology - September 21, 2020 Category: Neurology Source Type: research

Correction to Author ’s Name in Byline
This article was corre cted online.
Source: JAMA Neurology - September 8, 2020 Category: Neurology Source Type: research

The Complex Role of Racism in Stroke
This Viewpoint highlights the complex role of racism in stroke, and suggests a framework for understanding its effects.
Source: JAMA Neurology - August 21, 2020 Category: Neurology Source Type: research

Endovascular Treatment After Stroke Due to Large Vessel Occlusion for Patients Presenting Very Late
This case-control study examines the prevalence of salvageable tissues 16 hours or more from the time the patient was last known well after ischemic stroke due to emergent large vessel occlusion and investigates the effectiveness of endovascular treatment in delayed large vessel occlusion.
Source: JAMA Neurology - August 10, 2020 Category: Neurology Source Type: research

Perioperative Stroke Risk Reduction in Patients With Patent Foramen Ovale
This Viewpoint considers ischemic stroke risk for patients with a patent foramen ovale.
Source: JAMA Neurology - August 3, 2020 Category: Neurology Source Type: research

Prevalence of High-Risk Plaques and Risk of Stroke in Asymptomatic Carotid Stenosis
This meta-analysis examines the prevalence of high-risk plaques and the risk of ipsilateral ischemic events to assess the relevance and feasibility of using multimodal neurovascular imaging to perform risk-oriented selection for revascularization among patients with asymptomatic carotid stenosis.
Source: JAMA Neurology - August 3, 2020 Category: Neurology Source Type: research

New Horizons in Pharmacologic Therapy for Secondary Stroke Prevention
This narrative review summarizes the results of recent and ongoing randomized clinical trials of drugs for secondary stroke prevention.
Source: JAMA Neurology - July 27, 2020 Category: Neurology Source Type: research

Antihypertensive Medication Use Among Individuals With a History of Stroke and Hypertension, 2005 to 2016
This cross-sectional study investigates the adequacy of blood pressure control among stroke survivors and antihypertensive treatment trends using National Health and Nutrition Examination Survey data.
Source: JAMA Neurology - July 27, 2020 Category: Neurology Source Type: research

Stroke Thrombolysis With Tenecteplase to Reduce Spread of Coronavirus Disease 2019 and Alteplase Shortage
This Viewpoint advocates for expanded usage of tenecteplase in patients with stroke as a means of avoiding coronavirus disease 2019 spread and easing potential shortages of alteplase.
Source: JAMA Neurology - July 20, 2020 Category: Neurology Source Type: research

Characteristics of Recurrent Ischemic Stroke After ESUS
This secondary analysis of a randomized clinical trial assesses the subtype of recurrent ischemic stroke after embolic stroke of underdetermined source, the interaction with treatment assignment, and the consistency of cerebral location of the qualifying and recurrent strokes in the study population of the NAVIGATE-ESUS trial.
Source: JAMA Neurology - July 6, 2020 Category: Neurology Source Type: research

Prognosis of Cryptogenic Stroke With Patent Foramen Ovale at Older Ages and Implications for Trials
This systematic review and meta-analysis examines the recurrence of ischemic stroke and possible use of patent foramen ovale closure in patients aged 60 years or older.
Source: JAMA Neurology - July 6, 2020 Category: Neurology Source Type: research