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Specialty: Neurology
Source: JAMA Neurology

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Total 364 results found since Jan 2013.

Risk of Hemorrhagic Stroke in Patients With Coronavirus Disease 2019 —Reply
In Reply We thank Dr Silverman and colleagues for their interest in our study and providing us the opportunity to expand on our results. Among the 1916 patients who visited the emergency department or were hospitalized with coronavirus disease 2019 (COVID-19) in our study, 8 patients (0.4% [95% CI, 0.2%-0.8%]) had hemorrhagic stroke, including 7 with intracerebral hemorrhage and 1 with subarachnoid hemorrhage. Among these 8 patients, 4 strokes were attributed to anticoagulant use.
Source: JAMA Neurology - March 8, 2021 Category: Neurology Source Type: research

Risk of Hemorrhagic Stroke in Patients With Coronavirus Disease 2019
To the Editor We read with interest the article by Merkler et al regarding the increased incidence of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) compared with those with influenza. The authors also reported that 13% of patients with COVID-19 were receiving anticoagulation at the time of the stroke. Could the authors comment on the rate of anticoagulant use in patients with COVID-19 who did not have an ischemic stroke? This would also be helpful to assess the possibility that anticoagulation may have been protective.
Source: JAMA Neurology - March 8, 2021 Category: Neurology Source Type: research

Local Cerebral Recombinant Tissue Plasminogen Activator Concentrations During Acute Stroke
This study evaluates concentrations of local cerebral recombinant tissue plasminogen activator during mechanical thrombectomy treatment in acute stroke.
Source: JAMA Neurology - March 8, 2021 Category: Neurology Source Type: research

Reperfusion Treatment and Stroke Outcomes in Hospitals With Telestroke Capacity
This study describes differences in care patterns and outcomes among patients with acute ischemic stroke who present to hospitals with and without telestroke capacity.
Source: JAMA Neurology - March 1, 2021 Category: Neurology Source Type: research

Thrombectomy for Primary Distal Posterior Cerebral Artery Occlusion Stroke
This case-control study analyzes the clinical, functional, and safety outcomes associated with endovascular therapy for patients with posterior circulation distal, medium vessel occlusion.
Source: JAMA Neurology - February 22, 2021 Category: Neurology Source Type: research

Prediction of Early Neurological Deterioration in Minor Stroke and LVO Intended for Intravenous Thrombolysis
This cohort study aims to develop and validate an easily applicable predictive score of early neurological deterioration of presumed ischemic origin following intravenous thrombolysis in patients with minor stroke and large vessel occlusion (LVO).
Source: JAMA Neurology - January 11, 2021 Category: Neurology Source Type: research

Error in Figure
This article has been corrected online.
Source: JAMA Neurology - December 21, 2020 Category: Neurology Source Type: research

Prehospital Prediction of Large Anterior Vessel Occlusion
This cohort study performs external validations, head-to-head comparisons, and feasibility ratings of 7 scales used by emergency medical services in the field to predict symptomatic large anterior vessel occlusion among patients suspected of acute stroke.
Source: JAMA Neurology - November 30, 2020 Category: Neurology Source Type: research

Self-driven Prehospital Triage Decisions for Suspected Stroke
Setting the course for prehospital triage of patients with suspected stroke is challenging. Few would disagree, and to be frank, this is rather old news. Yet the critical question remains unsolved: how do we optimally drive prehospital triage decisions for patients with suspected stroke? Central to this question is the challenge of identifying stroke specifically due to large vessel occlusion (LVO) in the prehospital setting. Furthermore, the “best choice” among the various prehospital LVO screening tools available has not been clear. Although several versions have been developed, many had not been validated in the pre...
Source: JAMA Neurology - November 30, 2020 Category: Neurology Source Type: research

Error in P Value in Abstract and Results
The Original Investigation titled “Microbleeds and the Effect of Anticoagulation in Patients With Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Randomized Clinical Trial,” published online October 19, 2020, was corrected to fix an erroneous P value in the Abstract and the Results section. Th is article was corrected online.
Source: JAMA Neurology - November 30, 2020 Category: Neurology Source Type: research

Error in Data in Abstract
This article was correc ted online.
Source: JAMA Neurology - November 23, 2020 Category: Neurology Source Type: research

Ticagrelor Plus Aspirin in Preventing Disabling Stroke
This randomized clinical trial evaluates the superiority of ticagrelor added to aspirin in preventing disabling stroke and identifies factors associated with recurrent disabling stroke.
Source: JAMA Neurology - November 7, 2020 Category: Neurology Source Type: research

Association of Reperfusion After Thrombolysis With Clinical Outcome Across the 4.5- to 9-Hours and Wake-Up Stroke Time Window
This meta-analysis of 2 randomized clinical trials examines the association of reperfusion and reduced disability, including by onset-to-randomization time strata.
Source: JAMA Neurology - November 2, 2020 Category: Neurology Source Type: research

Microbleeds and the Effect of Anticoagulation in Patients With Embolic Stroke of Undetermined Source
This prespecified analysis of a randomized clinical trial investigates the effect of cerebral microbleeds on patients with embolic stroke of undetermined source taking either daily rivaroxaban or aspirin.
Source: JAMA Neurology - October 19, 2020 Category: Neurology Source Type: research

Cerebral Microbleeds and Antithrombotic Treatments —Stop Worrying About Bleeding
Cerebral microbleeds (CMBs) are found in up to one-third of patients with ischemic stroke. Because of their hemorrhagic histopathological substrate, they have been historically associated with a risk of intracerebral hemorrhage (ICH). This has led to concerns about the safety of anticoagulation use in patients with CMBs even in the context of high risk of recurrent ischemic stroke, such as in atrial fibrillation. However, growing evidence suggests that CMBs are not only markers of bleeding propensity but also markers of future ischemic events. To further evaluate both types of risks, an assessment of the number and anatomi...
Source: JAMA Neurology - October 19, 2020 Category: Neurology Source Type: research