• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Diffusion imaging and transcranial magnetic stimulation assessment of transcallosal pathways in chronic stroke
The corpus callosum is the largest white matter structure in the brain, consisting of neural fibre tracts that mediate interhemispheric communication. Such interhemispheric communication is especially important for movement, with inhibitory and excitatory signals transmitted between hemispheres based on whether unimanual or synchronous/asynchronous bimanual movement is performed (Carson, 2005). Deficits in motor function are commonly experienced following stroke and increasing evidence suggests that these deficits may be driven, in part, by disruption of transcallosal pathways (Murase et al., 2004; Duque et al., 2005; Gupt...
Source: Clinical Neurophysiology - January 14, 2015 Category: Neuroscience Authors: Cameron S. Mang, Michael R. Borich, Sonia M. Brodie, Katlyn E. Brown, Nicholas J. Snow, Katie P. Wadden, Lara A. Boyd Source Type: research

Behaviour of medial gastrocnemius motor units during postural reactions to external perturbations after stroke
The ankle plantarflexors are the main muscles controlling standing balance during anteriorly-directed sways (Di Giulio et al., 2009; Tokuno et al., 2007); this is often referred to as the “ankle strategy” (Winter et al., 1998). The medial gastrocnemius muscle has been suggested to be particularly active with anterior sways of increased magnitude (Di Giulio et al., 2009; Vieira et al., 2012) and gastrocnemius muscles have been shown to modulate with centre of mass (COM) velocity and anterior-posterior centre of pressure (APCOP) velocity and excursion during quiet stance (Gatev et al., 1999; Masani et al., 2003; Vieira et al., 2012).
Source: Clinical Neurophysiology - December 29, 2014 Category: Neuroscience Authors: C.L. Pollock, T.D. Ivanova, M.A. Hunt, S.J. Garland Source Type: research

Behavior of medial gastrocnemius motor units during postural reactions to external perturbations after stroke
The ankle plantar flexors are the main muscles controlling standing balance during anteriorly-directed sways (Di Giulio et al., 2009; Tokuno et al., 2007); this is often referred to as the “ankle strategy” (Winter et al., 1998). The medial gastrocnemius muscle has been suggested to be particularly active with anterior sways of increased magnitude (Di Giulio et al., 2009; Vieira et al., 2012) and gastrocnemius muscles have been shown to modulate with centre of mass (COM) velocity and anterior–posterior centre of pressure (APCOP) velocity and excursion during quiet stance (Gatev et al., 1999; Masani et al., 2003; Vieira et al., 2012).
Source: Clinical Neurophysiology - December 29, 2014 Category: Neuroscience Authors: C.L. Pollock, T.D. Ivanova, M.A. Hunt, S.J. Garland Source Type: research

1. Epileptic seizures in pediatric stroke: Data from the Italian Registry for Childhood Thrombosis
According to data from the Italian Registry for Childhood Thrombosis (R.I.T.I.), in about half cases diagnosis of pediatric stroke occurs after 24h from clinical onset (Baggio et al., SINP2013). The aim of the present study was to evaluate the frequency of seizures at stroke onset and their correlation with time to diagnosis in the pediatric stroke patients in the R.I.T.I. We selected the R.I.T.I. children with first acute arterial (AIS) or venous (CSVT) cerebral infarction occurring between January 2007 and June 2012; we studied prevalence, characteristics and recurrence of epileptic seizures, focusing on diagnostic delay.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: L. Baggio, S. Sartori, M. Nosadini, C. Gentilomo, P. Saracco, M. Agostini, B. Bassi, A. Palmieri, A.M. Laverda, P. Simioni, A. Suppiej, per il G.I.R.T.I. (Gruppo Italiano Registro Trombosi Infantili) Source Type: research

9. Brain network modulation following motor imagery BCI-assisted training after stroke
To evaluate the influence of Motor Imagery (MI) training assisted via Brain Computer Interface (BCI) on brain network organization in subacute stroke patients. We analyzed EEG-derived brain networks estimated before and after two training strategies (with and without BCI support); correlations between connectivity indices and clinical improvement were performed. Twenty-eight subacute stroke patients were enrolled and assigned to two groups: 14 patients underwent a one-month motor imagery (MI) training supported by a sensorimotor–based BCI (BCI group) while 14 underwent a similar MI training without BCI support (CTRL group).
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: F. Pichiorri, M. Petti, G. Morone, M. Molinari, L. Astolfi, F. Cincotti, M. Inghilleri, D. Mattia Source Type: research

87. Anodal transcranial direct current stimulation of motor cortex does not ameliorates spasticity in multiple sclerosis
Spasticity is a common disorder and a major cause of a long-term disability in patients with multiple sclerosis (MS). Transcranial direct current stimulation (tDCs) is a potential tool to improve motor deficits in several neurological disease and, recently, it has been proposed as effective in decreasing spasticity after stroke. To assess whether anodal tDCS is effective in modulating lower limb spasticity in MS patients. We performed a single-centre randomized, double-blind, sham-controlled study to investigate efficacy of anodal vs sham tDCs in 20 relapsing-remitting MS patients.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Iodice, F. Manganelli, L. Ruggiero, R. Dubbioso, L. Santoro Source Type: research

106. Deep repetitive transcranial magnetic stimulation (rTMS) with H-coil coupled with cycling in chronic lower limb dysfuncion after stroke: A randomized, placebo-controlled, crossover study
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of post-stroke deficits. We evaluated the feasibility, safety and efficacy of excitatory Hz rTMS with H-coil over the leg motor areas combined with active cycling on paretic lower limb motor function in chronic post-stroke. rTMS was delivered with the H-coil targeting the lower limbs (real or sham for 11 sessions over 3weeks, with cross-over after 4weeks wash-out, in 12 subjects with first stroke more than 6months before.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Chieffo, F. Giatsidis, E. Houdayer, M. Fichera, A. Nuara, E. Coppi, L. Ferrari, G. Di Maggio, R. Santangelo, A. Poggi, M. Sessa, M. Comola, A. Zangen, G. Comi, L. Leocani Source Type: research

112. Low frequency repetitive transcranial magnetic stimulation in early phase of rehabilitation of patients with post-stroke aphasia
About 50% of post-stroke patients remain aphasic a condition that greatly impede their reintegration to society. Results of Repetitive Transcranial Magnetic Stimulation (rTMS) as supplementary treatment for sub-acute post-stroke aphasia are controversial. We assessed the efficacy of inhibitory rTMS with conventional speech therapy to help recovery language performance in sub-acute stroke aphasia.In a randomised case-control double-blind study 12 non-fluent aphasic were consecutively enrolled. All patients suffered a first-ever stroke in the sub-acute stage defined as time since lesion onset from 1 month post-stroke.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Carrai, A. Grippo, A. Angelini, A. Vettori, T. Atzori, C. Falsini, M. Martini, A. Pizzi Source Type: research

Contributions of Motoneuron Hyperexcitability to Clinical Spasticity in Hemispheric Stroke Survivors
Spasticity, affecting up to 43% of chronic stroke survivors (Wissel et al., 2013), is diagnosed clinically as muscular hypertonia, coupled with other reflex disturbances. This hypertonia is defined as a velocity-dependent resistance to stretching due to exaggerated reflex responses (Lance, 1980). There are also concurrent mechanical changes of the muscular-tendon complex, which also contribute to increased muscle tone. Although spasticity can sometimes be beneficial for certain functional movements (e.g., making locomotion and body weight support possible), it is still a major neurological impairment that frequently limits...
Source: Clinical Neurophysiology - November 15, 2014 Category: Neuroscience Authors: Xiaogang Hu, Nina L. Suresh, Matthieu K. Chardon, William Z. Rymer Source Type: research

Cortical activation and inter-hemispheric sensorimotor coherence in individuals with arm dystonia due to childhood stroke
Motor disorders following childhood stroke are common (Lynch and Nelson, 2001), yet are insufficiently studied (Bejot et al., 2012). Of the observed post-stroke motor sequelae, childhood dystonia is the most frequently occurring disorder (Bejot et al., 2012). Dystonia, as it occurs in children, is defined as a movement disorder in which involuntary sustained or intermittent muscle contractions cause twisting and repetitive movements, abnormal postures, or both (Sanger et al., 2010). Post-stroke dystonia is most commonly observed on the side of the body contralateral to the stroke, and is referred to as hemidystonia.
Source: Clinical Neurophysiology - November 14, 2014 Category: Neuroscience Authors: Sahana N. Kukke, Ana Carolina de Campos, Diane Damiano, Katharine E. Alter, Nicholas Patronas, Mark Hallett Source Type: research

The P300 in middle cerebral artery strokes or hemorrhages: Outcome predictions and source localization
Stroke is the leading cause of disability and is the third leading cause of death worldwide (Murray and Lopez, 1997). According to the World Health Organisation, a total of 15 million people suffer a stroke each year. Strokes can principally be classified into two main categories, ischemic and hemorrhagic (Donnan et al., 2008). 85% of all strokes are of ischemic origin (Qureshi et al., 2001) and most commonly occur within the territory of the middle cerebral artery (MCA). The MCA supplies the lateral portion of the cerebral cortex (about 60–70% of the hemisphere).
Source: Clinical Neurophysiology - November 1, 2014 Category: Neuroscience Authors: Mana R. Ehlers, Carmen López Herrero, Andreas Kastrup, Helmut Hildebrandt Source Type: research

The P300 in middle cerebral artery strokes or hemorrhages: outcome predictions and source localisation
Stroke is the leading cause of disability and is the third leading cause of death worldwide (Murray and Lopez, 1997). According to the World Health Organisation, a total of 15 million people suffer a stroke each year. Strokes can principally be classified into two main categories, ischemic and hemorrhagic (Donnan et al., 2008). 85 % of all strokes are of ischemic origin (Qureshi et al., 2001) and most commonly occur within the territory of the middle cerebral artery (MCA). The MCA supplies the lateral portion of the cerebral cortex (about 60 % - 70 % of the hemisphere).
Source: Clinical Neurophysiology - November 1, 2014 Category: Neuroscience Authors: Mana R. Ehlers, Carmen López Herrero, Andreas Kastrup, Helmut Hildebrandt Source Type: research

Reply to “Perception of lower extremity loading in stroke”
As reflected by the comments of Kumar et al. (2014), there is an increasing interest in developing quantitative measurements of complex sensorimotor behaviors in people with neurologic injury or disease. In concept, our manuscript “Perception of lower extremity loads in stroke survivors” addresses one of these behaviors, which is likely to be important to gait function in stroke survivors. While we believe that impairment in load perception plays an important role in gait, Kumar et al. raise many important issues related to interpreting data from testing paradigms with higher complexity, and in extrapolating these labo...
Source: Clinical Neurophysiology - October 27, 2014 Category: Neuroscience Authors: Virginia W. Chu, T. George Hornby, Brian D. Schmit Tags: Letter to the Editor Source Type: research

Perception of lower extremity loading in stroke
We read with great interest the article entitled “Perception of lower extremity loads in stroke survivors” by Chu et al. (2014). There is a dearth of studies regarding perception of loading in stroke population. We applaud the authors for the contemporary thoughts on the method of measuring lower extremity dynamic load perception. We take this opportunity to share few scientific facts related to the scope of this article.
Source: Clinical Neurophysiology - October 25, 2014 Category: Neuroscience Authors: Senthil N.S. Kumar, Leonard H Joseph, Ahmad Pharmy Jalil Tags: Letter to the Editor Source Type: research

P11. Quality of Life after pediatric ischemic stroke: Five year follow-up of swiss children
Children after pediatric arterial ischemic stroke (AIS) are known to suffer from neurological and neuropsychological impairments but limited data is available concerning quality of life (QoL) outcome. The aim of this present study is to examine long-term effects on QoL in a population-based AIS sample from Switzerland.
Source: Clinical Neurophysiology - October 1, 2014 Category: Neuroscience Authors: S. Kornfeld, S. Winkelbeiner, M. Studer, E. Boltshauser, A. Capone Mori, A. Datta, J. Fluss, D. Mercati, A. Hackenberg, E. Keller, O. Maier, J.P. Marcoz, G.P. Ramelli, C. Poloni, R. Schmid, T. Schmitt-Mechelke, E Wehrli, T. Heinks, M. Steinlin Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20