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Total 3622 results found since Jan 2013.

Non-calcified active atherosclerosis plaque detection with 18F-NaF and 18F-FDG PET/CT dynamic imaging
This study was aimed to assess the behavior of 18F-sodium fluoride (18F-NaF) and 18F-fluorodeoxyglucose (18F-FDG) uptake in the aorta and iliac arteries as a function of plaque density on CT images. We report metabolically active artery plaques associated to inflammation in the absence of calcification. 18 elderly volunteers were recruited and imaged with computed tomography (CT) and positron emission tomography (PET) with 18F-NaF and 18F-FDG. A total of 1338 arterial segments were analyzed, 766 were non-calcified and 572 had calcifications. For both 18F-NaF and 18F-FDG, the mean SUV values were found statistically signifi...
Source: Australasian Physical and Engineering Sciences in Medicine - January 30, 2023 Category: Biomedical Engineering Source Type: research

Intracranial carotid artery calcification morphology differs in patients with lacunar and non-lacunar acute ischemic strokes
CONCLUSIONS: Our study suggests that intimal ICAC pattern is associated with lacunar stroke and may serve as a marker for lacunar stroke etiology, possibly strengthen the relation between endothelial dysfunction and lacunar stroke.PMID:36692888 | DOI:10.1111/ene.15704
Source: Atherosclerosis - January 24, 2023 Category: Cardiology Authors: Federico Mazzacane Beatrice Del Bello Federica Ferrari Alessandra Persico Elisa Rognone Anna Pichiecchio Alessandro Padovani Anna Cavallini Andrea Morotti Francesco Arba Source Type: research

Reduction in wound healing complications and infection rate by lumbar CSF drainage after decompressive hemicraniectomy
CONCLUSIONS: In patients after DHC and open basal cisterns on postoperative CT, lumbar drainage appears to be safe and reduces the rate of surgical wound revisions and intracranial infection after DHC while the risk for provoking paradoxical herniation is low early after surgery.PMID:36681955 | DOI:10.3171/2022.10.JNS221589
Source: Journal of Neurosurgery - January 22, 2023 Category: Neurosurgery Authors: Peter Truckenmueller Anton Fr üh Stefan Wolf Katharina Faust Nils Hecht Julia Onken Robert Ahlborn Peter Vajkoczy Anna Zdunczyk Source Type: research

Unlucky numbers: Fighting murder convictions that rest on shoddy stats
LEIDEN, THE NETHERLANDS— When a Dutch nurse named Lucia de Berk stood trial for serial murder in 2003, statistician Richard Gill was aware of the case. But he saw no reason to stick his nose into it. De Berk was a pediatric nurse at Juliana Children’s Hospital in The Hague. In 2001, after a baby died while she was on duty, a colleague told superiors that De Berk had been present at a suspiciously high number of deaths and resuscitations. Hospital staff immediately informed the police. When investigators reexamined records from De Berk’s shifts, they found 10 suspicious incidents. Three other hospitals where D...
Source: Science of Aging Knowledge Environment - January 19, 2023 Category: Geriatrics Source Type: research

Reliability of respiratory-gated real-time two-dimensional cine incorporating deep learning reconstruction for the assessment of ventricular function in an adult population
This study aimed to assess the image quality and accuracy of respiratory-gated real-time two-dimensional (2D) cine incorporating deep learning reconstruction (DLR) for the quantification of biventricular volumes and function compared with those of the standard reference, that is, breath-hold 2D balanced steady-state free precession (bSSFP) cine, in an adult population. Twenty-four patients (15 men, mean age 50.7  ± 16.5 years) underwent cardiac magnetic resonance for clinical indications, and 2D DLR and bSSFP cine were acquired on the short-axis view. The image quality scores were based on three main criteria: blood-t...
Source: The International Journal of Cardiovascular Imaging - January 17, 2023 Category: Radiology Source Type: research

FDA Approves Lecanemab, a New Alzheimer ’s Drug
On Jan. 6, the U.S. Food and Drug Administration (FDA) approved a new drug to treat Alzheimer’s disease in its early stages. Lecanemab, which will be available under the name Leqembi, can slow the cognitive decline associated with Alzheimer’s disease by 27%, according to data submitted to the FDA by the drug’s developers, Eisai and Biogen. It’s only the second medication to show any improvement in neurodegeneration, a key criterion in the FDA’s consideration for approval. “For a long time, this is what we have been looking for,” says Dr. Sam Gandy, professor of neurology and psychi...
Source: TIME: Health - January 6, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs healthscienceclimate Source Type: news

Association of aortic arch calcification with acute ischemic stroke subtypes and endovascular thrombectomy outcomes
This study analyzed AAC on computer tomography (CT) scans, with the goal of predicting the subtypes and outcomes of ischemic stroke patients undergoing endovascular thrombectomy (EVT).
Source: Journal of Vascular and Interventional Radiology : JVIR - January 2, 2023 Category: Radiology Authors: Yu-Li Lee, Jiann-Der Lee, Hsu-Huei Weng, An-Ni Wang, Yuan-Hsiung Tsai Tags: Clinical Study Source Type: research

Long-term improvement of symptoms of angina pectoris after successful revascularization of coronary artery chronic total occlusions
Conclusions. Successful CTO PCI is associated with better long-term relief of symptoms of angina pectoris compared to failed CTO PCI.PMID:36587829 | DOI:10.1080/14017431.2022.2161621
Source: Scandinavian Cardiovascular Journal - January 1, 2023 Category: Cardiology Authors: Hirokazu Miyashita Lauri Mansikkaniemi Juha Sinisalo Juhani Stewart Petri Laine Source Type: research