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Condition: Parkinson's Disease
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Total 1347 results found since Jan 2013.
Parkinson ’ s Patients Get More Mobility And Better Balance With Whole Body Vibration Therapy
I’ve always believed that with a little coaxing, your body can self-heal – and the same is true for your brain.
Conventional doctors will never tell you this. For them, being a physician means managing symptoms with Big Pharma meds.
But for years, I’ve been helping patients recover using dietary changes, lasers, stem cells, and hyperbaric oxygen (HBOT). These therapies help your body heal itself.
No Big Pharma drug can do this.
But I recently began researching another natural therapy – called Whole Body Vibration, or WBV – that can help Parkinson’s patients regain their mobility and balance.
WBV isn’t new. It...
Source: Al Sears, MD Natural Remedies - August 28, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Natural Cures Source Type: news
The role of the indoles in microbiota-gut-brain axis and potential therapeutic targets: A focus on human neurological and neuropsychiatric diseases
Neuropharmacology. 2023 Aug 22:109690. doi: 10.1016/j.neuropharm.2023.109690. Online ahead of print.ABSTRACTAt present, a large number of relevant studies have suggested that the changes in gut microbiota are related to the course of nervous system diseases, and the microbiota-gut-brain axis is necessary for the proper functioning of the nervous system. Indole and its derivatives, as the products of the gut microbiota metabolism of tryptophan, can be used as ligands to regulate inflammation and autoimmune response in vivo. In recent years, some studies have found that the levels of indole and its derivatives differ signifi...
Source: Neuropharmacology - August 24, 2023 Category: Drugs & Pharmacology Authors: Yi Zhou Yue Chen Hui He Meichang Peng Meiqin Zeng Haitao Sun Source Type: research
Investigation of Pancreatic-beta cells Role in the Biological Process of Ageing
CONCLUSION: Aging accelerates beta cell senescence by generating premature cell senescence, which is mostly mediated by high glucose levels. Despite higher plasma glucose levels, hepatic gluconeogenesis accelerates and adipose tissue lipolysis rises, resulting in an increase in free fatty acid levels in the blood and worsening insulin resistance throughout the body.PMID:37608675 | DOI:10.2174/1871530323666230822095932
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 23, 2023 Category: Endocrinology Authors: Rishabh Chaudhary Janvi Khanna Manni Rohilla Sumeet Gupta Seema Bansal Source Type: research
Detection of Ferroptosis in Models of Brain Diseases
Methods Mol Biol. 2023;2712:233-251. doi: 10.1007/978-1-0716-3433-2_21.ABSTRACTFerroptosis is a regulated form of non-apoptotic cell death driven by iron-dependent lipid peroxidation. In the past decade, ferroptosis has been reported to be involved in the pathological role in the central nervous system degenerative diseases (e.g., Alzheimer's disease, Huntington's disease, and Parkinson's disease), stroke, traumatic brain injury, and brain tumor. However, how to reliably detect and classify ferroptosis from other cell death in pathological conditions remains a great challenge, especially in primary brain cells and brain ti...
Source: Mol Biol Cell - August 14, 2023 Category: Molecular Biology Authors: Danmin Shen Fei Yang Qian Li Source Type: research
Methods to Study Inflammasome Activation in the Central Nervous System: Immunoblotting and Immunohistochemistry
Methods Mol Biol. 2023;2696:223-238. doi: 10.1007/978-1-0716-3350-2_15.ABSTRACTThe inflammasome is a multiprotein complex that is responsible for mounting an innate immune response through the activation of caspase-1 and the cleavage of interleukin-1β. This multiprotein complex plays an important role in a variety of central nervous system (CNS) diseases and conditions such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, and traumatic brain injury, among others. Here we describe methodological procedures to carry out immunoblotting and immunohistochemical techniques used to study inflammasome sign...
Source: Molecular Medicine - August 14, 2023 Category: Molecular Biology Authors: Brianna Cyr Juan Pablo de Rivero Vaccari Source Type: research
Multicohort cross-sectional study of cognitive and behavioural digital biomarkers in neurodegeneration: the Living Lab Study protocol
Introduction and aims
Digital biomarkers can provide a cost-effective, objective and robust measure for neurological disease progression, changes in care needs and the effect of interventions. Motor function, physiology and behaviour can provide informative measures of neurological conditions and neurodegenerative decline. New digital technologies present an opportunity to provide remote, high-frequency monitoring of patients from within their homes. The purpose of the living lab study is to develop novel digital biomarkers of functional impairment in those living with neurodegenerative disease (NDD) and neurological condi...
Source: BMJ Open - August 3, 2023 Category: General Medicine Authors: Crook-Rumsey, M., Daniels, S. J. C., Abulikemu, S., Lai, H., Rapeaux, A., Hadjipanayi, C., Soreq, E., Li, L. M., Bashford, J., Jeyasingh-Jacob, J., Gruia, D. C., Lambert, D., Weil, R., Hampshire, A., Sharp, D. J., Haar, S. Tags: Open access, Neurology Source Type: research
Molecules, Vol. 28, Pages 5824: Neurological Applications of Celery (Apium graveolens): A Scoping Review
In conclusion, the safety of A. graveolens extract and NBP can be further investigated clinically on different neurological disorders based on their potential role in different targeted pathways.
Source: Molecules - August 2, 2023 Category: Chemistry Authors: Terence Yew Chin Tan Xin Yi Lim Nor Azrina Norahmad Hemahwathy Chanthira Kumar Bee Ping Teh Nai Ming Lai Ami Fazlin Syed Mohamed Tags: Review Source Type: research
Impact of injection guidance techniques on the efficacy and safety of incobotulinumtoxinA for sialorrhea
Background:SIAXI (NCT02091739), a double-blind, randomized, placebo-controlled study, assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U in patients with sialorrhea due to Parkinson ’s disease (PD), atypical parkinsonism, stroke or traumatic brain injury. This subgroup analysis assessed the impact of injection guidance technique.
Source: Parkinsonism and Related Disorders - August 1, 2023 Category: Neurology Authors: W. Jost, F. Pagan, O. Michel, C. Oehlwein, J. Slawek, A. Bogucki, S. Ochudlo, M. Banach, B. Flatau-Baqu é, J. Csikos, A. Blitzer Source Type: research
Placebo-controlled, randomized, double-blind study of incobotulinumtoxinA for sialorrhea
Background:This pivotal phase III study, SIAXI, investigated the efficacy and safety of incobotulinumtoxinA for the treatment of chronic sialorrhea due to Parkinson disease (PD), atypical parkinsonism, stroke, or traumatic brain injury (TBI).
Source: Parkinsonism and Related Disorders - August 1, 2023 Category: Neurology Authors: W. Jost, A. Friedman, O. Michel, C. Oehlwein, J. Slawek, A. Bogucki, S. Ochudlo, M. Banach, F. Pagan, B. Flatau-Baqu é, J. Csikos, C.J. Cairney, A. Blitzer Source Type: research
