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White matter microstructure and verbal fluency
We examined white matter correlates of semantic (Category Fluency Animals) and phonemic or lexical fluency (COWAT FAS) after stroke, accounting for stroke severity measured with the Nation al Institutes of health Stroke Scale (NIHSS), age, sex, and level of education. White matter fibre density and cross-section measures were automatically extracted from 72 tracts, using MRtrix and TractSeg software in 72 ischaemic stroke survivors assessed 3 months after their event. We conducted re gression analyses separately for phonemic and semantic fluency for each tract. Worse semantic fluency was associated with lower fibre densit...
Source: Anatomy and Embryology - October 17, 2022 Category: Anatomy Source Type: research

Evaluation of Diffusion –Perfusion Mismatch in Acute Ischemic Stroke with a New Automated Perfusion-Weighted Imaging Software: A Retrospective Study
ConclusionsThe iStroke automatic processing of ADC and PWI is a reliable software for the identification of diffusion –perfusion mismatch in acute ischemic stroke.
Source: Neurology and Therapy - October 6, 2022 Category: Neurology Source Type: research

Peer-support interventions for women with cardiovascular disease: protocol for synthesising the literature using an evidence map
Introduction The leading cause of death for women is cardiovascular disease (CVD), including ischaemic heart disease, stroke and heart failure. Previous literature suggests peer support interventions improve self-reported recovery, hope and empowerment in other patient populations, but the evidence for peer support interventions in women with CVD is unknown. The aim of this study is to describe peer support interventions for women with CVD using an evidence map. Specific objectives are to: (1) provide an overview of peer support interventions used in women with ischaemic heart disease, stroke and heart failure, (2) identif...
Source: BMJ Open - October 5, 2022 Category: General Medicine Authors: Parry, M., Visintini, S., Johnston, A., Colella, T. J., Kapur, D., Liblik, K., Gomes, Z., Dancey, S., Liu, S., Goodenough, C., Hay, J. L., Noble, M., Adreak, N., Robert, H., Tang, N., O'Hara, A., Wong, A., Mullen, K.-A. Tags: Open access, Cardiovascular medicine Source Type: research

Differential associations between pre-diabetes, diabetes and stroke occurrence among West Africans
CONCLUSION: Pre-DM is strongly and independently associated with stroke in Africans. Improving glycemic control through screening, healthy lifestyle and pharmacotherapy at a population level may be strategic in reducing the rising burden of stroke in Africa.PMID:36194925 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106805
Source: Atherosclerosis - October 4, 2022 Category: Cardiology Authors: Fred Stephen Sarfo Bruce Ovbiagele Joshua Akinyemi Onoja Akpa Albert Akpalu Kolawole Wahab Godwin Ogbole Reginald Obiako Morenikeji Komolafe Lukman Owolabi Godwin Osaigbovo Carolyn Jenkins Adekunle Fakunle Abiodun Adeoye Dan Lackland Donna Arnett Hemant K Source Type: research

The PRESTO study: awareness of stroke symptoms and time from onset to intervention
In conclusion, our results may suggest that an informative campaign can be successf ul in making people rapidly aware of stroke onset, with the consequent rapid access to hospitals. Considering the changing of way of access to information, we think that an extensive multimedia campaign should be evaluated in the next future.
Source: Neurological Sciences - October 3, 2022 Category: Neurology Source Type: research

The Impact of Standardized Health Education in Patients with Ischemic Stroke on Patient Management Satisfaction and Quality of Clinical Management Services
CONCLUSION: The application of standardized health education in patients with ischemic stroke has certain clinical value.PMID:36118830 | PMC:PMC9473899 | DOI:10.1155/2022/5698400
Source: Computational and Mathematical Methods in Medicine - September 19, 2022 Category: Statistics Authors: Jing Chen Lin Xiang Source Type: research

Implementation of an Advanced Practice Registered Nurse–Led Clinic to Improve Follow-up Care for Post–Ischemic Stroke Patients
CONCLUSION: An APRN-led clinic can improve follow-up care and may reduce unplanned 30-day readmissions for post–ischemic stroke patients. Further work is needed to determine the impact of alternative approaches such as telehealth.
Source: Journal of Neuroscience Nursing - September 10, 2022 Category: Neuroscience Tags: Clinical Nursing Focus Source Type: research

Emergency medical service utilization among acute ischemic stroke patients in Beijing: An observational study
ConclusionThis study demonstrated an inadequate use of EMS among AIS patients in Beijing, especially in rural areas, and revealed several associated factors. Enhanced education programs and EMS accessibility are necessary particularly for high-risk individuals and regions.
Source: Frontiers in Neurology - September 6, 2022 Category: Neurology Source Type: research

O20 Thrombectomy for medium vessel occlusions: treatment effect of successful recanalization on long term functional outcome
ConclusionTICI 2b recanalization in MeVO increased probability of good outcome from 27% to 58%, TICI 3 recanalization did not further improve prognosis. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep and Fabian Flottmann are consultants for Eppdata.Milani Deb-Chatterji has received research grants from the Werner Otto Stiftung.Götz Thomalla received fees as consultant from Acandis, Bayer, and Portola, and fees as lecturer from Acandis, Alexion, Amarin, Bayer, Boehringer-Ingelheim, BristolMyersSquibb, Daiichii Sankyo, Portola, and Stryker.Jens Fiehler received research...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Bechstein, M., Broocks, G., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Meyer, L., Hanning, U., Thomalla, G., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P46 How much of the improvement in functional outcome after successful recanalization is explained by follow-up infarct volume reduction?
Conclusions57% of the improvement of functional outcome after successful recanalization is explained by follow-up infarct volume reduction. Results reflect established pathophysiological assumptions and confirm the value of infarct volume as imaging endpoint in clinical trials.ReferencesBoers AMM, Jansen IGH, Brown S, et al. Mediation of the relationship between endovascular therapy and functional outcome by follow-up infarct volume in patients with acute ischemic stroke. Jama Neurology 2019;76:194–202. DOI: 10.1001/Jamaneurol.2018.3661 Do you have any conflict of interest to declare?: YesConflict of Interest Stateme...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Broocks, G., Austein, F., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Thomalla, G., Hanning, U., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P83 The relationship of functional outcome after mechanical thrombectomy and serum glucose is partially mediated by edema formation
ConclusionEdema formation explains 15% of the total adverse effects of high blood glucose levels. Major pathways might include other direct effects of high blood glucose, such as altered vessel wall and thrombus characteristics and higher thrombogenicity of the cerebral blood flow.ReferencesThorén, M., et al. "Predictors for Cerebral Edema in Acute Ischemic Stroke Treated with Intravenous Thrombolysis." Stroke 2017;48(9): 2464–2471. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep is a consultant for Eppdata.Jens Fiehler received research support from: German Minis...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Hanning, U., Fiehler, J., Broocks, G. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

Health-related quality of life and associated factors among hypertensive patients
CONCLUSIONS: Hypertensives had low HRQOL scores in all domains. Factors affecting their HRQOL should be taken into account when treating these patients.PMID:36027221 | DOI:10.1097/01.hjh.0000837808.51473.2f
Source: Atherosclerosis - August 26, 2022 Category: Cardiology Authors: Duy Tran Cong Hoa Chau Ngoc Source Type: research

Impact of non-adherence to direct oral anticoagulants amongst Swedish patients with non-valvular atrial fibrillation: results from a real-world cost-utility analysis
CONCLUSION: Adherence improving interventions for NVAF patients on DOACs such as chronic disease co-management and patient education can be cost-saving and cost-effective, within a range of costs that appear reasonable to the Swedish healthcare system.PMID:35997241 | DOI:10.1080/13696998.2022.2116848
Source: Journal of Medical Economics - August 23, 2022 Category: Health Management Authors: C Blomstr öm Lundqvist S Sj älander L A Garcia Rodriguez Ö Åkerborg G Jin A Caleyachetty M Huelsebeck K Bowrin B Schaefer H Mahdessian L Hofmeister L Å Levin Source Type: research

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