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Characteristics of drug-related problems among hospitalized ischemic stroke patients in China
Conclusion Drug-related problems are relatively common in hospitalized ischemic stroke patients in China, and treatment safety is the major DRP type. Pharmacist intervention can identify and resolve pertinent DRPs to optimize medication therapy.
Source: International Journal of Clinical Pharmacy - June 29, 2020 Category: Drugs & Pharmacology Source Type: research

Reduction in the doses of direct oral anticoagulants and risk of ischemic stroke events: A hospital survey.
Abstract Inappropriately reduced doses (IRDs) of direct oral anticoagulants (DOACs) are common in clinical practice. We performed a retrospective review using electronic medical records of St. Marianna University School of Medicine Hospital (a 1200-bed teaching hospital in Japan) to address the prevalence of IRDs and patient-related factors that result in IRDs. We also surveyed DOAC-treated patients who were hospitalized due to a stroke during the 5-year study period to analyze the association between stroke events and IRDs. We found that one in five patients who were newly prescribed a DOAC was treated with IRDs....
Source: Biological and Pharmaceutical Bulletin - May 11, 2020 Category: Drugs & Pharmacology Authors: Ueda A, Toki S, Kitayama C, Akazawa M Tags: Biol Pharm Bull Source Type: research

Trends of antihypertensive agents in patients with hypertension and coronary artery disease in a tertiary hospital of China
Conclusion The compliance to guidelines is overall well for patients with hypertension and coronary artery disease, but improvements is needed for patients with type 2 diabetes. Multi-center studies with large-scale data are required to further assess the usage of antihypertensive agents in patients.
Source: International Journal of Clinical Pharmacy - February 19, 2020 Category: Drugs & Pharmacology Source Type: research

An Assessment of Patients Factors Effect on Prescriber Adherence to Ischemic Stroke Secondary Prevention Guidelines.
CONCLUSION: Adherence to stroke secondary prevention guidelines was suboptimal especially in the antihypertensive prescription component. Further assessments and evaluations are required improve guidelines adherence. PMID: 31971113 [PubMed - as supplied by publisher]
Source: Current Clinical Pharmacology - January 22, 2020 Category: Drugs & Pharmacology Authors: Al Qawasmeh M, Alhusban A, Alfwaress F, El-Salem K Tags: Curr Clin Pharmacol Source Type: research

The association of clopidogrel and 2-oxo-clopidogrel plasma levels and the 40  months clinical outcome after primary PCI
Conclusion Clopidogrel dose-adjusted plasma concentration in STEMI patients, as well as multivessel coronary artery disease, showed significance in predicting an unfavorable composite clinical outcome after 40-month follow-up.
Source: International Journal of Clinical Pharmacy - October 26, 2018 Category: Drugs & Pharmacology Source Type: research

Predictors of Direct Oral Anticoagulants Utilization for Thromboembolism Prevention in Atrial Fibrillation.
CONCLUSION: To the best of our knowledge, this is the first observational study finding that concomitant use of clopidogrel reduced the likelihood of DOAC utilization while prescription by a neurologist increased the probability of receiving a DOAC over warfarin in patients with AF.This article is open to POST-PUBLICATION REVIEW. Registered readers (see "For Readers") may comment by clicking on ABSTRACT on the issue's contents page. PMID: 28459661 [PubMed - in process]
Source: Journal of Pharmacy and Pharmaceutical Sciences - May 2, 2017 Category: Drugs & Pharmacology Tags: J Pharm Pharm Sci Source Type: research

Pharmacists' role in a hospital's initiative to become a certified primary stroke center.
CONCLUSION: By participating in the implementation of a number of transformative initiatives, the pharmacy department played an important role in enabling the medical center to provide consistent, excellent care for all patients with stroke as it prepared for certification as a PSC. PMID: 26896520 [PubMed - as supplied by publisher]
Source: American Journal of Health-System Pharmacy : AJHP - February 22, 2016 Category: Drugs & Pharmacology Authors: Gilmer A, Sweeney L, Nakajima S Tags: Am J Health Syst Pharm Source Type: research

An audit of the pharmacological management of ischaemic stroke patients in a metropolitan Australian hospital
Conclusion The majority of the cohort was discharged on the appropriate evidence based medications for the management of secondary stroke. Further improvement may be achieved by pharmacist intervening as part of a multidisciplinary team.
Source: International Journal of Clinical Pharmacy - January 31, 2015 Category: Drugs & Pharmacology Source Type: research

Appropriateness of Prescribing Dabigatran Etexilate and Rivaroxaban in Patients With Nonvalvular Atrial Fibrillation: A Prospective Study.
CONCLUSIONS:: Inappropriate use of DE and rivaroxaban in patients with NVAF is frequent and possibly leads to AEs. Reinforcing education of health care professionals and patients is needed. Collaboration with clinical pharmacists can contribute to better use. PMID: 24982310 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - June 30, 2014 Category: Drugs & Pharmacology Authors: Larock AS, Mullier F, Sennesael AL, Douxfils J, Devalet B, Chatelain C, Dogné JM, Spinewine A Tags: Ann Pharmacother Source Type: research