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Stroke risk in treatment of type 2 diabetes in China: a 7 year retrospective cohort study
Publication date: November 2016 Source:The Lancet Diabetes & Endocrinology, Volume 4, Supplement 1 Author(s): Rui Liu, Qing Wang, Vivian Szeto, Andrew Barszczyk, Tianru Jin, Edoardo Mannucci, Hong-Shuo Sun, Zhong-Ping Feng Background Diabetes and stroke are leading causes of death and disability, and major public health concerns in China, which accounts for 25% of patients with diabetes worldwide. Type 2 diabetes is an independent risk factor for cerebral ischaemia and accounts for about 20% of stroke cases. We previously showed that KATP channel activation provides neuroprotection against cerebral ischaemia and t...
Source: The Lancet Diabetes and Endocrinology - November 17, 2016 Category: Endocrinology Source Type: research

A Network Pharmacology Approach for Exploring the Mechanisms of < em > Panax notoginseng < /em > Saponins in Ischaemic Stroke
CONCLUSIONS: The ameliorative effects of PNS against IS were predicted to be associated with the regulation of the IGF1-PI3K-Akt signalling pathway. Ginsenoside Re and ginsenoside Rb1 may play an important role in the treatment of IS.PMID:34434246 | PMC:PMC8382556 | DOI:10.1155/2021/5582782
Source: Evidence-based Complementary and Alternative Medicine - August 26, 2021 Category: Complementary Medicine Authors: Cong Wang Hao Chen Shi-Tang Ma Bin-Bin Mao Yu Chen Hao-Nan Xu Hao Yu Source Type: research

A Study of the Relationship between Blood Glucose and Serum Insulin in Acute Cerebrovascular Disease
CONCLUSION: A rise in blood glucose and serum insulin levels is associated with the incidence and prognosis of acute cerebrovascular disease, and it is positively correlated with the severity of the acute cerebrovascular disease.PMID:35958906 | PMC:PMC9359818 | DOI:10.1155/2022/9041551
Source: Evidence-based Complementary and Alternative Medicine - August 12, 2022 Category: Complementary Medicine Authors: Lei Zhao Shuangling Xiu Lina Sun Zhijing Mu Junling Fu Source Type: research

Gal-geun-dang-gwi-tang improves diabetic vascular complication in apolipoprotein E KO mice fed a western diet
Conclusions: These findings suggest that GGDGT attenuates endothelial dysfunction via improvement of the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signalling pathway and improves insulin sensitivity in diabetic atherosclerosis.
Source: BMC Complementary and Alternative Medicine - November 22, 2014 Category: Complementary Medicine Authors: So LeeYun LeeJung ChoiMin KhoJung YoonSun ShinDae KangHo Lee Source Type: research

More than a stretch: Yoga’s benefits may extend to the heart
As a long-time yoga enthusiast, I’m always happy to hear about benefits newly attributed to this ancient practice. Doing yoga for a few hours each week helps me feel calmer and more balanced, both physically and mentally. Now, new research suggests that my habit also may be helping my heart. A recent review of yoga and cardiovascular disease published in the European Journal of Preventive Cardiology indicates that yoga may help lower heart disease risk as much as conventional exercise, such as brisk walking. As I write in the April issue of the Harvard Heart Letter, the studies in the review looked at different types...
Source: New Harvard Health Information - April 15, 2015 Category: Consumer Health News Authors: Julie Corliss Tags: Complementary and alternative medicine Heart Health alternative therapy cardiovascular disease exercise yoga Source Type: news

SGLT2 Inhibitors: Emerging Roles in the Protection Against Cardiovascular and Kidney Disease Among Diabetic Patients.
Conclusion: SGLT2 inhibitors are novel antidiabetic medications with immense utility in the management of patients with T2DM. Furthermore, SGLT2 inhibitors have demonstrated to reduce the progression to advanced forms of kidney disease and its associated complications. These medications should be front and center in the management of patients with diabetic kidney disease with and without chronic kidney disease as they confer protection against cardiovascular/renal death and improve all-cause mortality. Future studies should evaluate the benefits and implications of early initiation of SGLT2 inhibitors, as well as the long-...
Source: International Journal of Nephrology and Renovascular Disease - November 7, 2020 Category: Urology & Nephrology Tags: Int J Nephrol Renovasc Dis Source Type: research

Inhibition of the Immunoproteasome Subunit LMP7 Ameliorates Cerebral White Matter Demyelination Possibly via TGF < em > β < /em > /Smad Signaling
CONCLUSIONS: The possible mechanism underlying this was attributed to that the immunoproteasome regulates TGFβ/Smad signaling-mediated neuroinflammation and oligodendrocyte remyelination.PMID:34675988 | PMC:PMC8526201 | DOI:10.1155/2021/6426225
Source: Evidence-based Complementary and Alternative Medicine - October 22, 2021 Category: Complementary Medicine Authors: Xingyong Chen Nannan Yao Zejing Lin Yinzhou Wang Source Type: research

Anti-Diabesity Middle Eastern Medicinal Plants and Their Action Mechanisms
Evid Based Complement Alternat Med. 2022 Jul 18;2022:2276094. doi: 10.1155/2022/2276094. eCollection 2022.ABSTRACTOver the last four decades, the escalation in diabetes and obesity rates has become epidemic all over the world. Diabesity describes the strong link between T2D and obesity. It correlates deeper with the elevated risks of developing cardiovascular disease hypertension, stroke, and several malignancies. Therapeutic usage of medicinal plants and natural products in the treatment of diabetes and obesity has long been known to physicians of Greco-Arab and Islamic medicine. Improved versions of their abundant medici...
Source: Evidence-based Complementary and Alternative Medicine - July 28, 2022 Category: Complementary Medicine Authors: Bashar Saad Abdalsalam Kmail Sameena Z H Haq Source Type: research