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Tamoxifen promotes white matter recovery and cognitive functions in male mice after chronic hypoperfusion
Publication date: Available online 5 October 2019Source: Neurochemistry InternationalAuthor(s): Yuxue Chen, Yeye Tian, Hao Tian, Qibo Huang, Yongkang Fang, Wei Wang, Yue Wan, Dengji Pan, Minjie XieAbstractCerebral white matter lesions (WMLs) induced by chronic cerebral hypoperfusion are one of the major components of stroke pathology and closely associated with cognitive impairment. However, the repair and related pathophysiology of white matter after brain injury remains relatively elusive and underexplored. Successful neuroregeneration is a method for the potential treatment of CNS disorders. A non-steroidal estrogen rec...
Source: Neurochemistry International - October 6, 2019 Category: Neuroscience Source Type: research

Using Dental Pulp Stem Cells for Stroke Therapy
Conclusion and Future Perspectives Stem cell-based therapy is a promising alternative for stroke treatment. While stem cells from different sources, including induced PSC, ESC, MSC, and NSC, have been investigated, using NSC and enhancing the natural mechanisms is most appropriate for brain repair. In preclinical models of stroke, stem cell transplantation has led to positive outcomes through a variety of cellular and molecular mechanisms, many being mediated by the array of beneficial factors produced by the cells. Recent advances in cellular reprogramming have provided alternative sources of NSC to be investigated, allo...
Source: Frontiers in Neurology - April 28, 2019 Category: Neurology Source Type: research

This Vitamin Could Save Your Life
For years, I’ve recommended that my patients take a special family of super-nutrients with the power to boost their health and save their lives in at least a half a dozen ways. I’m talking about tocotrienols, an especially potent form of vitamin E. Tocotrienols, which comprise four out of the eight types of vitamin E, are powerful antioxidants that until recently were ignored by mainstream medicine. But the patients at my wellness clinic and regular readers of my newsletter will know that I’ve recommended them as a critical nutrient for years. And I do it because almost daily I observe the effects of the...
Source: Al Sears, MD Natural Remedies - March 26, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Nutrition antioxidants brain Cancer heart heart disease nutrients supplements vitamins Source Type: news