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Drug: Diazepam

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Total 41 results found since Jan 2013.

Pharmacological prevention of postictal agitation after electroconvulsive therapy —A systematic review and meta-analysis
ConclusionFor clinical practice, we believe that our results indicate that dexmedetomidine should be considered for the prevention of PIA in patients that have previously experienced PIA.
Source: Frontiers in Psychiatry - April 20, 2023 Category: Psychiatry Source Type: research

DBI/ACBP is a targetable autophagy checkpoint involved in aging and cardiovascular disease
In conclusion, it appears that extracellular DBI/ACBP can be targeted to combat age-associated cardiovascular disease.Abbreviations: BMI: body mass index; CDKN2A/p16: cyclin dependent kinase inhibitor 2A; CVD: cardiovascular disease; DBI/ACBP: diazepam binding inhibitor, acyl-CoA binding protein; ELISA: enzyme-linked immunosorbent assay; GABA: gamma-aminobutyric acid; GABR: gamma-aminobutyric acid type A receptor.PMID:36579946 | DOI:10.1080/15548627.2022.2160565
Source: Autophagy - December 29, 2022 Category: Cytology Authors: L éa Montégut Adrien Joseph Hui Chen Mahmoud Abdellatif Christoph Ruckenstuhl Isabelle Martins Frank Madeo Guido Kroemer Source Type: research

What It ’s Like to Live With Stiff Person Syndrome
twIn an emotional social-media video posted Dec. 8, singer Celine Dion informed fans that she has been diagnosed with a rare neurological disease called stiff person syndrome. A diagnosis wasn’t easy or straightforward. “I’ve been dealing with problems with my health for a long time…we now know this is what’s been causing all of the spasms that I’ve been having,” said Dion, who is 54. Here’s what to know about the condition and what it feels like. What is stiff person syndrome? According to the National Institute of Neurological Disorders and Stroke, stiff person syndrome has...
Source: TIME: Health - December 9, 2022 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Disease healthscienceclimate Source Type: news

Potentiation of GABAergic synaptic transmission by diazepam acutely increases resting beat-to-beat blood pressure variability in young adults
Am J Physiol Regul Integr Comp Physiol. 2022 Mar 29. doi: 10.1152/ajpregu.00291.2021. Online ahead of print.ABSTRACTResting beat-to-beat blood pressure variability is a powerful predictor of cardiovascular events and end-organ damage. However, its underlying mechanisms remain unknown. Herein, we tested the hypothesis that a potentiation of GABAergic synaptic transmission by diazepam would acutely increase resting beat-to-beat blood pressure variability. In 40 (17 females) young, normotensive subjects, resting beat-to-beat blood pressure (finger photoplethysmography) was continuously measured for 5 to 10 min, 60 min after t...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - March 29, 2022 Category: Physiology Authors: Andr é L Teixeira Massimo Nardone Milena Samora Igor Alexandre Fernandes Plinio Santos Ramos Jeann L Sabino-Carvalho Djalma Rabelo Ricardo Philip J Millar Lauro C Vianna Source Type: research

Antiepileptic drugs for the primary and secondary prevention of seizures after stroke
CONCLUSIONS: There is insufficient evidence to support the routine use of AEDs on the primary and secondary prevention of seizures after stroke. Further well-conducted studies are warranted for this important clinical problem.PMID:35129214 | DOI:10.1002/14651858.CD005398.pub4
Source: Cochrane Database of Systematic Reviews - February 7, 2022 Category: General Medicine Authors: Richard S Chang William Cy Leung Michael Vassallo Lucy Sykes Emma Battersby Wood Joseph Kwan Source Type: research