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Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
Clin Exp Hypertens. 2022 Jan 3:1-9. doi: 10.1080/10641963.2021.2022688. Online ahead of print.ABSTRACTIn 2020, the National Center for Cardiovascular Diseases with National Committee on Hypertension Management in Primary Health Care in China issued revised national clinical practice guidelines on the management of hypertension in primary health care based on the 2018 Chinese guidelines for the management of hypertension. To evaluate adherence to the guidelines, this retrospective study assessed the real-world status of antihypertensive drug prescribing for Chinese patients with hypertension, classified by comorbidity: coro...
Source: Clinical and Experimental Hypertension - January 3, 2022 Category: Cardiology Authors: Renren Yang Jia Tang Yunping Zhuo Ming Kuang Hongying Liu Source Type: research

Tachycardia: The hidden cardiovascular risk factor in uncomplicated arterial hypertension.
Abstract Early detection and management of elevated blood pressure is crucial in reducing the burden of cardiovascular disease (CVD). The importance of an absolute risk assessment and patient risk stratification has been highlighted in the European hypertension guidelines since 2003. Amongst numerous risk factors influencing patient prognosis, elevated heart rate (HR) has been indicated as important predictor of future risk of hypertension, coronary heart disease, sudden cardiac death, heart failure, CVD, stroke, total cancer and mortality. Given that resting HR can be easily determined in clinical practice and mo...
Source: Cardiology Journal - February 25, 2019 Category: Cardiology Authors: Cierpka-Kmieć K, Hering D Tags: Cardiol J Source Type: research

Secondary CV Prevention in South America in a Community Setting: The PURE Study
ConclusionsThere are large gaps in the use of proven medications for secondary prevention of cardiovascular disease in South America. Strategies to improve the sustained use of these medications will likely reduce cardiovascular disease burden substantially.
Source: Global Heart - July 10, 2018 Category: Cardiology Source Type: research

Blood pressure treatment levels and choice of antihypertensive agent in people with diabetes mellitus: an overview of systematic reviews
Conclusion: The available evidence supports treatment in people with type 2 diabetes and SBP more than 140 mmHg, using any of the major antihypertensive drug classes.
Source: Journal of Hypertension - January 31, 2017 Category: Cardiology Tags: Reviews Source Type: research

Turkish registry for diagnosis and treatment of acute heart failure: TAKTIK study.
CONCLUSION: Compared to previous data collected around the world, AHF patients in Turkey were younger, had more frequently valvular heart disease as the underlying cause, and were more noncompliant with medical treatment, but overall mortality was lower. Drugs shown to reduce mortality, and which also form the basis of guideline-directed medical therapy, are still used inadequately. PMID: 28045409 [PubMed - in process]
Source: Turk Kardiyoloji Dernegi arsivi - November 30, 2016 Category: Cardiology Authors: Eren M, Zoghi M, Tuncer M, Çavuşoğlu Y, Demirbağ R, Şahin M, Serdar OA, Onrat E, Mutlu H, Dursunoğlu D, Yılmaz MB, Temizhan A, TAKTIK Investigators Tags: Turk Kardiyol Dern Ars Source Type: research

Socioeconomic factors and use of secondary preventive therapies for cardiovascular diseases in South Asia: The PURE study
Conclusion The use of secondary preventive drug therapies in patients with known CHD or stroke in South Asia is low with over 80% receiving none of the effective drug treatments. Low household wealth is the most important determinant.
Source: European Journal of Preventive Cardiology - September 11, 2015 Category: Cardiology Authors: Gupta, R., Islam, S., Mony, P., Kutty, V. R., Mohan, V., Kumar, R., Thakur, J., Shankar, V. K., Mohan, D., Vijayakumar, K., Rahman, O., Yusuf, R., Iqbal, R., Shahid, M., Mohan, I., Rangarajan, S., Teo, K. K., Yusuf, S. Tags: Original scientific papers Source Type: research

Effects of blood pressure-lowering on outcome incidence in hypertension: 5. Head-to-head comparisons of various classes of antihypertensive drugs – overview and meta-analyses
Conclusions: The results of all available evidence from head-to-head drug class comparisons do not allow the formulation of a fixed paradigm of drug choice valuable for all hypertensive patients, but the differences found may suggest specific choices in specific conditions, or preferable combinations of drugs.
Source: Journal of Hypertension - June 5, 2015 Category: Cardiology Tags: Reviews Source Type: research

Trends in Antihypertensive Medication Use and Blood Pressure Control Among Adults With Hypertension in Germany.
CONCLUSIONS: Increased and improved antihypertensive use might be a main contributor to the decrease in BP observed in Germany in the last decade. However, there are still socio-demographic and health disparities in hypertension treatment and control. PMID: 25968124 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - May 11, 2015 Category: Cardiology Authors: Sarganas G, Knopf H, Grams D, Neuhauser HK Tags: Am J Hypertens Source Type: research

Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs – Overview and meta-analyses
Conclusion: BP lowering by all classes of antihypertensive drugs is accompanied by significant reductions of stroke and major cardiovascular events. This supports the concept that reduction of these events is because of BP lowering per se rather than specific drug properties. However, evidence of risk reduction of other events and particularly mortality was obtained so far with some drug classes only. As a result of marked differences in the trial design, total cardiovascular risk, SBP/DBP differences and statistical power, comparisons of meta-analyses of different drug-specific placebo-controlled RCTs appear unwarranted.
Source: Journal of Hypertension - January 6, 2015 Category: Cardiology Tags: Reviews and Meta-Analyses Source Type: research

Peripheral artery disease and outcomes after myocardial infarction: An individual-patient meta-analysis of 28,771 patients in CAPRICORN, EPEHESUS, OPTIMAAL and VALIANT
Abstract: Objectives: To examine the prevalence of peripheral artery disease (PAD) and the relationship between PAD and cardiovascular (CV) outcomes in subjects with left ventricular systolic dysfunction, heart failure or both after acute myocardial infarction (MI).Background: PAD is associated with poorer prognosis in patients with stable and unstable coronary heart disease but whether PAD is associated with worse outcomes following substantial acute MI is unknown.Methods: Univariate and multivariate Cox proportional hazards modelling was used to compare clinical outcomes in an individual-patient meta-analysis of 4 trials...
Source: International Journal of Cardiology - November 29, 2012 Category: Cardiology Authors: Sally C. Inglis, Judith Bebchuk, Sultan A. Al-Suhaim, Jessica Case, Marc A. Pfeffer, Scott D. Solomon, Yingxin (Rachel) Hou, Bertram Pitt, Henry J. Dargie, Ian Ford, John Kjekshus, Faiez Zannad, Kenneth Dickstein, John J.V. McMurray Tags: Original Articles Source Type: research