Cover 1
Publication date: December 2019Source: Global Heart, Volume 14, Issue 4Author(s): (Source: Global Heart)
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

Table of Contents
Publication date: December 2019Source: Global Heart, Volume 14, Issue 4Author(s): (Source: Global Heart)
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

General Information
Publication date: December 2019Source: Global Heart, Volume 14, Issue 4Author(s): (Source: Global Heart)
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

Global Capacity Building for Global Challenges in Cardiovascular Disease
Publication date: December 2019Source: Global Heart, Volume 14, Issue 4Author(s): Diederick E. Grobbee (Source: Global Heart)
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

Long-Term Outcomes of a Cohort of Hypertensive Subjects in Rural Ecuador
This study sought to evaluate the feasibility and the overall results of a hypertension control program, based mainly on a network of community nonprofessional health promoters, in the poor rural region of Borbon (Ecuador).MethodsThis is a prospective cohort study describing the results of a program of hypertension diagnosis, treatment and follow-up from 2004 to 2015 in the area, carried out mainly by the health promoters.ResultsThe number of hypertensive patients identified and followed over the years increased from 1,024 in 2004 to 1,733 in 2015. The percentage of patients with no visits during a year was reduced to
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

Association Between Perceived Neighborhood Characteristics and Carotid Artery Intima-Media Thickness: Cross-Sectional Results From the ELSA-Brasil Study
This study aimed to investigate the association between perceived neighborhood characteristics and subclinical atherosclerosis in a large sample of adults, using cross-sectional data from the ELSA-Brasil (Brazilian Longitudinal Study of Adult Health).MethodsParticipants free of clinical coronary artery disease answered a questionnaire designed to assess their perceptions regarding 6 neighborhood dimensions: social cohesion, walkability, availability of healthy food, safety, witnessed violence, and personal victimization. The scores of each domain were used as independent variables. Common carotid intima-media thickness (CC...
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

Developing the Core Pillars of Training Global Cardiovascular Health Researchers: Companionship, Light, and Fuel
Publication date: December 2019Source: Global Heart, Volume 14, Issue 4Author(s): Lijing L. Yan, Rajesh Vedanthan, George A. Mensah, Biraj Karmacharya, Archana Shrestha, Annette Fitzpatrick, Ha Anh Duc, Nikhil Tandon, Victor G. Davila-Roman, Mark D. Huffman, J. Jaime Miranda, Vilma Irazola, Rajendra Koju, Brad Newsome, Salim Yusuf (Source: Global Heart)
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

Strategic, Successful, and Sustained Synergy: The Global Alliance for Chronic Diseases Hypertension Program
Publication date: December 2019Source: Global Heart, Volume 14, Issue 4Author(s): Ruth Webster, Gary Parker, Stephane Heritier, Rohina Joshi, Karen Yeates, Patricio Lopez-Jaramillo, J. Jaime Miranda, Brian Oldenburg, Bruce Ovbiagele, Mayowa Owolabi, David Peiris, Devarsetty Praveen, Abdul Salam, Jon-David Schwalm, K.R. Thankappan, Nihal Thomas, Sheldon Tobe, Rajesh Vedanthan (Source: Global Heart)
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

WHF Staff and Board Members
Publication date: December 2019Source: Global Heart, Volume 14, Issue 4Author(s): (Source: Global Heart)
Source: Global Heart - November 12, 2019 Category: Cardiology Source Type: research

Effects of HIV Infection on Pulmonary Artery Pressure in Children
ConclusionsART-exposed HIV infection is associated with higher estimated PAP. Reduced RV systolic function is seen in ART-naïve HIV infection. Lower respiratory tract infection partly explains lower systolic RV function in ART-naïve relative to ART-exposed HIV infection. (Source: Global Heart)
Source: Global Heart - October 12, 2019 Category: Cardiology Source Type: research

Electrocardiographic Evidence of Cardiac Disease by Sex and HIV Serostatus in Mbarara, Uganda
Publication date: Available online 1 October 2019Source: Global HeartAuthor(s): Katherine Kentoffio, Alfred Albano, Bruce Koplan, Maggie Feng, Rahul G. Muthalaly, Jeffrey I. Campbell, Ruth Sentongo, Russell P. Tracy, Robert Peck, Samson Okello, Alexander C. Tsai, Mark J. Siedner (Source: Global Heart)
Source: Global Heart - October 2, 2019 Category: Cardiology Source Type: research

Evaluating the World Heart Federation's 25 by 25: The Forgotten Millions
Publication date: Available online 21 September 2019Source: Global HeartAuthor(s): Dominique Vervoort (Source: Global Heart)
Source: Global Heart - September 22, 2019 Category: Cardiology Source Type: research

Renal Disease Is Associated With Poor Outcomes Following Isolated Coronary Artery Bypass Grafting
ConclusionsPre-existing renal disease is significantly associated with 30-day and long-term mortality, length of intensive care unit and hospital stay as well as several other post-operative complications. (Source: Global Heart)
Source: Global Heart - September 14, 2019 Category: Cardiology Source Type: research

Effect of a Community Health Worker-Based Approach to Integrated Cardiovascular Risk Factor Control in India: A Cluster Randomized Controlled Trial
ConclusionsA population-based strategy of integrated risk factor management through community health workers led to improved systolic blood pressure in hypertension, an inconclusive effect on fasting blood glucose in diabetes, and no demonstrable effect on smoking. (Study of a Community-Based Approach to Control Cardiovascular Risk Factors in India [SEHAT]; NCT02115711). (Source: Global Heart)
Source: Global Heart - September 14, 2019 Category: Cardiology Source Type: research

Cover 1
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Table of Contents
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Raising Cardiovascular Health in Low Resource Settings: Challenges and Road Maps Ahead
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): Diederick E. Grobbee (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

World Heart Federation Roadmap for Heart Failure
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): João Pedro Ferreira, Sarah Kraus, Sharon Mitchell, Pablo Perel, Daniel Piñeiro, Ovidiu Chioncel, Roberto Colque, Rudolf de Boer, Juan Esteban Gomez-Mesa, Hugo Grancelli, Carolyn S.P. Lam, Antoni Martinez-Rubio, John J.V. McMurray, Alexandre Mebazaa, Gurusher Panjrath, Ileana L. Piña, Mahmoud Sani, David Sim, Mary Walsh, Clyde Yancy (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

A Roadmap on the Prevention of Cardiovascular Disease Among People Living With Diabetes
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): Sharon Mitchell, Belma Malanda, Albertino Damasceno, Robert H. Eckel, Dan Gaita, Kornelia Kotseva, James L. Januzzi, George Mensah, Jorge Plutzky, Maksym Prystupiuk, Lars Ryden, Jorge Thierer, Salim S. Virani, Laurence Sperling (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Atrial Fibrillation in Africa—An Under-Reported and Unrecognized Risk Factor for Stroke: A Systematic Review
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): Maartje S. Jacobs, Marinus van Hulst, Abiodun M. Adeoye, Robert G. Tieleman, Maarten J. Postma, Mayowa O. OwolabiAbstractOver three-quarters of deaths from cardiovascular disease and diabetes occur in low- and middle-income countries, which include many African countries. Global studies showed that the prevalence of the cardiac arrhythmia atrial fibrillation (AF) appeared to be lower in Africa. A systematic search of PubMed and African Journals Online was conducted to determine the prevalence of AF and associated stroke risk factors in Afric...
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction: Is it Affected by Treatment Strategy?
ConclusionsThe incidence of CIN was slightly lower in PIS as compared to PPCI; however, this reduction was not statistically significant. The independent predictors of CIN were advanced age, history of diabetes mellitus and hypertension, high dose of contrast agent, and cardiogenic shock. (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Barriers and Facilitators to the Use of Cardiovascular Fixed-Dose Combination Medication (Polypills) in Andhra Pradesh, India: A Mixed-Methods Study
ConclusionsIn a market in which polypill use is licensed, their availability and use is very low. Lack of prescription of polypills was the predominant barrier to polypill use; therefore, making polypills with drugs that are more acceptable and at different available strengths, in conjunction with broader prescriber education and training, may improve their use. (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

The Importance of Conscious Sedation for Life-Saving Valve Procedures in Patients With Rheumatic Heart Disease From Low- to Middle-Income Countries
ConclusionsThis simple model of conscious sedation was able to promote anxiolysis, analgesia, and comfort for the procedure without serious hemodynamic effects, which can be a reasonable choice in developing countries. (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Current State of Hypertrophic Cardiomyopathy Clinical Trials
ConclusionsThe study revealed a low number of trials, lack of geographic diversity, and scarcity of published results concerning HCM clinical trials. Proper management of HCM trials is of vast importance to achieve effective therapies. (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Equivalence in Active Pharmaceutical Ingredient of Generic Antihypertensive Medicines Available in Nigeria (EQUIMEDS): A Case for Further Surveillance
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): Julie Redfern, Harparkash Kaur, Rufus Adesoji Adedoyin, Sandra Ofori, Raghupathy Anchala, Ajay S. Vamadevan, Luciano De Andrade, Jose Zelaya, Dina Balabanova, Mahmoud Umar SaniAbstractBackgroundWidespread access to good quality antihypertensive medicines is a critical component for reducing premature cardiovascular disease (CVD) mortality. Poor-quality medicines pose serious health concerns; however, there remains a knowledge gap about the quality of cardiovascular medicines available in low- and middle-income countries.ObjectivesThe aim of ...
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Clinical, Angiographic Characteristics and In-Hospital Outcomes of Smoker and Nonsmoker Patients After Primary Percutaneous Coronary Intervention
This study was planned to assess the differences in the clinical characteristics, angiographic characteristics, and in-hospital outcomes of smokers and nonsmokers after primary percutaneous coronary intervention at a tertiary care hospital in Karachi, Pakistan.MethodsWe included patients between 40 and 80 years of age diagnosed with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention from July 1, 2017, to March 31, 2018. Clinical and angiographic characteristics and in-hospital outcomes were obtained from the cases submitted to the National Cardiovascular Data Registry's Cath...
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

WHF Staff and Board Members
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

General Information
Publication date: September 2019Source: Global Heart, Volume 14, Issue 3Author(s): (Source: Global Heart)
Source: Global Heart - August 24, 2019 Category: Cardiology Source Type: research

Access to Essential Medicines for Circulatory Diseases: A Call to Action
Publication date: Available online 2 August 2019Source: Global HeartAuthor(s): Martin McKee, Oana Scarlatescu, David Wood, Jean-Luc Eiselé, Pablo Perel, Salim Yusuf (Source: Global Heart)
Source: Global Heart - August 4, 2019 Category: Cardiology Source Type: research

Cardiovascular Health in a National Sample of Venezuelan Subjects Assessed According to the AHA Score: The EVESCAM
This study sought to determine the prevalence of CHS categories in a nationally representative sample of Venezuelan adults.MethodsEVESCAM (Venezuelan Study of Cardio-Metabolic Health) was a national population-based, cross-sectional, randomized cluster sampling study performed from July 1, 2014 to January 31, 2017, which assessed 3,454 adults, age ≥20 years, with a response rate of 77.3%. The American Heart Association's CHS evaluates 4 behaviors (smoking, body mass index, physical activity, and diet) and 3 risk factors (total cholesterol, blood pressure, and blood glucose), assigning 1 point to those meting an ideal be...
Source: Global Heart - July 20, 2019 Category: Cardiology Source Type: research

The Evidence for a Population Screening Program for Rheumatic Heart Disease in India
Publication date: Available online 17 July 2019Source: Global HeartAuthor(s): Jessica Ying-Yi Xie, Matthew R. Solomons, Mahmood Ahmad (Source: Global Heart)
Source: Global Heart - July 18, 2019 Category: Cardiology Source Type: research

The Kathmandu Declaration on Global CVD/Hypertension Research and Implementation Science: A Framework to Advance Implementation Research for Cardiovascular and Other Noncommunicable Diseases in Low- and Middle-Income Countries
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): Angela Aifah, Juliet Iwelunmor, Constantine Akwanalo, Jeroan Allison, Alemayehu Amberbir, Kwaku P. Asante, Ana Baumann, Angela Brown, Mark Butler, Milena Dalton, Victor Davila-Roman, Annette L. Fitzpatrick, Meredith Fort, Robert Goldberg, Austrida Gondwe, Duc Ha, Jiang He, Mina Hosseinipour, Vilma Irazola, Jemima Kamano (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Stakeholder Engagement in Late-Stage Translation Research and Implementation Science: Perspectives From the National Heart, Lung, and Blood Institute
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): George A. Mensah, Jennifer S. Curry, Michael M. Engelgau, Lenora E. JohnsonAbstractStakeholder engagement is crucial for turning discovery into health. Although it is a highly effective approach for research in general, it is an essential component in late-stage translation research and implementation science in which the central objective is to accelerate the sustained uptake and integration of proven-effective interventions into routine clinical and public health practice. Where the stakeholder is an entire community, the term community engagem...
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Table of Contents
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

General Information
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Assessing Stakeholder Engagement for Translation Research and Implementation Science in Low- and Middle-Income Countries: Lessons From Ghana, Guatemala, India, Kenya, Malawi, Nepal, Rwanda, and Vietnam
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): Emmanuel Peprah, Juliet Iwelunmor, LeShawndra Price (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Stakeholder Engagement in Planning the Design of a National Needs Assessment for Cardiovascular Disease Prevention and Management in Nepal
ConclusionsThe stakeholder engagement process positively affected the design of our research. This study provides important insights for future researchers that aim to engage stakeholders in national-level assessment programs in the health care system in the context of Nepal. (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Systematic Review of Hypertension and Diabetes Burden, Risk Factors, and Interventions for Prevention and Control in Malawi: The NCD BRITE Consortium
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): Alemayehu Amberbir, Sabrina H. Lin, Joshua Berman, Adamson Muula, Darren Jacoby, Emily Wroe, Cecilia Maliwichi-Nyirenda, Victor Mwapasa, Amelia Crampin, Martha Makwero, Emmanuel Singogo, Sam Phiri, Stephen Gordon, Sheldon W. Tobe, Jones Masiye, Brad Newsome, Mina Hosseinipour, Moffat J. Nyirenda, Joep J. van OosterhoutAbstractRecent studies have found an increasing burden of noncommunicable diseases in sub-Saharan Africa. A compressive search of PubMed, Medline, EMBASE, and the World Health Organization Global Health Library databases was underta...
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Adopting Task-Shifting Strategies for Hypertension Control in Ghana: Insights From a Realist Synthesis of Stakeholder Perceptions
ConclusionsThrough the application of a realist synthesis of stakeholder perceptions, the study identified factors likely to enhance the adoption of an evidence-based strategy for hypertension control in Ghana. The lessons learned will help shape the translation of evidence in real-world settings, and could be valuable in future planning to enhance the adoption of evidence-based strategies for hypertension control in LMICs. (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Capacity and Readiness for Implementing Evidence-Based Task-Strengthening Strategies for Hypertension Control in Ghana: A Cross-Sectional Study
ConclusionsThe majority of CHOs in this study were aware of lifestyle modifications such as diet modifications and increase in physical activity. However, their knowledge was limited in the blood pressure threshold for initiating treatment and in the knowledge of first-line hypertension medication, irrespective of the number of years practiced. Training on hypertension is also low. However, CHOs are motivated to control hypertension at the community level. Community-level interventions such as TASSH can leverage on their motivation to demonstrate an impact on hypertension control. (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): Ana A. Baumann, Vincent Mutabazi, Angela L. Brown, Cole Hooley, Dominic Reeds, Cecile Ingabire, Vedaste Ndahindwa, Aurore Nishimwe, W. Todd Cade, Lisa de las Fuentes, Enola K. Proctor, Stephen Karengera, Kenneth B. Schecthman, Charles W. Goss, Kevin Yarasheski, Brad Newsome, Eugene Mutimura, Victor G. Davila-RomanAbstractBackgroundCardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in low- and middle-income countries, and hypertension (HTN) is a major risk factor for CVD. Although effective evidence-based in...
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Stakeholder Engagement in Late-Stage Translation Phase 4 Research for Noncommunicable Diseases in Low- and Middle-Income Countries: What Works and Why—The Vietnam Experience (UMMS–Vietnam Team)
ConclusionsMultiple layers of stakeholders and communities in Vietnam are fully engaged with, and have contributed significantly to, our ongoing hypertension control research project in Northern Vietnam. (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

The Malawi NCD BRITE Consortium: Building Research Capacity, Implementation, and Translation Expertise for Noncommunicable Diseases
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): Joep J. van Oosterhout, Mina Hosseinipour, Adamson S. Muula, Alemayehu Amberbir, Emily Wroe, Josh Berman, Cecilia Maliwichi-Nyirenda, Victor Mwapasa, Amelia Crampin, Martha Makwero, Emmanuel Singogo, Satish Gopal, Ulrika Baker, Samuel Phiri, Stephen B. Gordon, Sheldon Tobe, Jonathan Chiwanda, Jones Masiye, John Parks, Collins MitamboAbstractAfrica is experiencing an increasing prevalence of noncommunicable diseases (NCD). However, few reliable data are available on their true burden, main risk factors, and economic impact that are needed to infor...
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Stakeholder Engagement in the Translation of a Hypertension Control Program to Guatemala's Public Primary Health Care System: Lessons Learned, Challenges, and Opportunities
ConclusionsWe identified lessons learned, challenges, and opportunities during the adaptation process. Findings will inform ongoing stakeholder engagement during the study implementation and future scale-up and efforts to translate evidence-based hypertension control strategies to low- and middle-income countries globally. (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Strategies for Stakeholder Engagement and Uptake of New Intervention: Experience From State-Wide Implementation of mHealth Technology for NCD Care in Tripura, India
ConclusionsMultiple strategies, based on implementation principles, are required for successful scaling up of research-based interventions. (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Strategies for Effective Stakeholder Engagement in Strengthening Referral Networks for Management of Hypertension Across Health Systems in Kenya
ConclusionsEarly stakeholder identification and engagement using the International Association of Public Participation model eased explanation of research objectives, building consensus, and shaping the interventions to improve the referral process. (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

WHF Staff and Board Members
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): (Source: Global Heart)
Source: Global Heart - July 17, 2019 Category: Cardiology Source Type: research

Distribution of Cardiovascular Health by Individual- and Neighborhood-Level Socioeconomic Status: Findings From the Jackson Heart Study
Publication date: Available online 10 June 2019Source: Global HeartAuthor(s): Randi E. Foraker, Christopher Bush, Melissa A. Greiner, Mario Sims, Kamal Henderson, Sakima Smith, Aurelian Bidulescu, Abigail B. Shoben, N. Chantelle Hardy, Emily O'BrienAbstractBackgroundData demonstrate a positive relationship between socioeconomic status (SES) and cardiovascular health (CVH).ObjectiveTo assess the association between individual- and neighborhood-level SES and CVH among participants of the JHS (Jackson Heart Study), a community-based cohort of African Americans in Jackson, Mississippi.MethodsWe included all JHS participants wi...
Source: Global Heart - June 11, 2019 Category: Cardiology Source Type: research

Beyond Sharing and Shifting: Raising the Bar for Global Rheumatic Heart Disease Control
Publication date: Available online 18 May 2019Source: Global HeartAuthor(s): Scott S. Lee, Rajesh Vedanthan (Source: Global Heart)
Source: Global Heart - May 20, 2019 Category: Cardiology Source Type: research

The Neglected Component of Cardiovascular Care: Dispelling the Myths
Publication date: Available online 18 May 2019Source: Global HeartAuthor(s): Dominique Vervoort (Source: Global Heart)
Source: Global Heart - May 20, 2019 Category: Cardiology Source Type: research