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Specialty: Neurology
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Total 260 results found since Jan 2013.
Trends in age and sex-specific prevalence of cancer and cancer subtypes in acute ischemic stroke from 2007-2019
To describe age and sex-specific prevalence of cancer in acute ischemic stroke (AIS) hospitalizations in the United States over the last decade.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2022 Category: Neurology Authors: Fadar Oliver Otite, Sana Somani, Ehimen Aneni, Emmanuel Akano, Smit D. Patel, Nnabuchi Anikpezie, Olaoluwatomi Lamikanra, Hesham Masoud, Julius Gene Latorre, Seemant Chaturvedi, Prachi Mehndiratta Source Type: research
Annexin A1 upregulates hematoma resolution via the FPR2/p-ERK(1/2)/DUSP1/CD36 signaling pathway after germinal matrix hemorrhage
Exp Neurol. 2022 Oct 21:114257. doi: 10.1016/j.expneurol.2022.114257. Online ahead of print.ABSTRACTGerminal matrix hemorrhage (GMH) is one of the leading causes of morbidity and mortality in preterm infants in the United States, with little progress made in its clinical management. Blood clots disrupting normal cerebrospinal fluid circulation and absorption after germinal matrix hemorrhage are key contributors towards post-hemorrhagic hydrocephalus development. n-formyl peptide receptor 2 (FPR2), a G-protein-coupled receptor, has been associated with the activation of p-ERK1/2, which in turn promotes the transcription of ...
Source: Experimental Neurology - October 24, 2022 Category: Neurology Authors: Jerry J Flores Yan Ding Prativa Sherchan John H Zhang Jiping Tang Source Type: research
Broadening Our SCOPE of Understanding Patent Foramen Ovale High-risk Features and Stroke
Paradoxical embolization of a blood clot of presumed venous origin through a patent foramen ovale (PFO) is increasingly recognized as a legitimate cause of otherwise cryptogenic ischemic stroke (CIS). The term PFO-associated stroke has been proposed, as has where and how to classify this entity in the nomenclature of various ischemic stroke subtyping systems. PFOs are common, with prevalence as high as 25% in the general population. The prevalence of PFO is further increased in patients with CIS (overall 2.9 times higher), and especially so in the subset of younger patients (<55 years, 5.1 times higher). One estimate of...
Source: JAMA Neurology - October 10, 2022 Category: Neurology Source Type: research
Outcomes among patients with primary angiitis of the CNS: A Nationwide United States analysis
Primary angiitis of the central nervous system (PACNS) is a relapsing-remitting disease with a heterogeneous course. Case series have delineated the long-term disease course but not acute outcomes or their determinants. The national United States hospital burden of PACNS has not been quantified.
Source: Journal of Stroke and Cerebrovascular Diseases - September 23, 2022 Category: Neurology Authors: Smit D. Patel, Fadar Otite Oliver, Ahmed Elmashad, Neel Patel, Tapan Mehta, Jason Hinman, David S. Liebeskind, Aneesh B. Singhal, Anne Ducros, Jeffrey L. Saver Source Type: research
Trends in admissions for intracranial dissections in the United States
Intracranial artery dissection (IAD) is rarer than cervical artery dissections (CeAD), and information is based on limited series with small cohorts. There are only several small-scale studies attempting to characterize the natural history of the disease. Herein, we analyze the prevalence of IADs in hospitalized patients using a national database.
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2022 Category: Neurology Authors: Waseem Wahood, Giuseppe Lanzino, Zafer Keser Source Type: research
Evaluation of the Rapid Arterial oCclusion Evaluation (RACE) scale in Upstate South Carolina, USA
This study was designed to determine if the Rapid Arterial oCclusion Evaluation scale is a valid prehospital stroke assessment for identifying large vessel occlusion patients in South Carolina, USA.
Source: Journal of Stroke and Cerebrovascular Diseases - September 8, 2022 Category: Neurology Authors: Samadhi Thavarajah, Zachary Langston, Adam Sarayusa, Lauren A. Fowler, Sanjeev Sivakumar, Neel Shah Source Type: research
Stroke in sickle cell disease and the promise of recent disease modifying agents
Sickle cell disease (SCD) is an inherited hemoglobinopathy affecting approximately 100,000 individuals in the United States. Cerebrovascular disease is among the most common and debilitating complications of SCA, with 53% experiencing silent cerebral infarct by age 30 and 3.8% experiencing overt stroke by age 40  years. This review highlights the burden of cerebrovascular disease in SCD, including both stroke and silent cerebral infarct (SCI). We then discuss the pathophysiology of stroke and cerebral fat embolism in the absence of a patent foramen ovale.
Source: Journal of the Neurological Sciences - September 8, 2022 Category: Neurology Authors: Ava Runge, Danielle Brazel, Zahra Pakbaz Tags: Review Article Source Type: research
Trends in post-discharge prophylactic anticoagulant use among stroke patients in the United States between 2006 and 2019
Stroke is an independent risk factor for venous thromboembolism (VTE). Although the risk of VTE persists after hospital discharge, information on the utilization of anticoagulants among stroke patients after discharge remains limited.
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2022 Category: Neurology Authors: Ghadeer K. Dawwas, Adam Cuker, Aaron Rothstein, Sean Hennessy Source Type: research
The effects of racism and resilience on Black stroke- survivor quality of life: Study protocol and rationale for a mixed-methods approach
This study aims to examine the effects of experiences of racism and resilience on Black SS QoL during early stroke recovery. This article presents the study protocol.Methods and analysesThis will be a prospective observational mixed-methods study. Black community-dwelling adults who are within 4 weeks of a stroke will be eligible for inclusion. Baseline measures will include the exposure variables of experiences of racism and resilience. Covariates measured at baseline include sociodemographic variables (age, sex, marital status, education, income, health insurance, employment status, number of people in household, residen...
Source: Frontiers in Neurology - August 10, 2022 Category: Neurology Source Type: research
Prevalence, predictors, and prognosis of mortality among elderly stroke patients with convulsive status epilepticus in the United States
Stroke is the most common cause of epilepsy in the elderly. However, despite the high mortality typically associated with convulsive status epilepticus (CSE), there is a dearth of nationwide data on the magnitude and association of CSE with mortality among hospitalized elderly with stroke in the United States.
Source: Journal of the Neurological Sciences - July 17, 2022 Category: Neurology Authors: Alain Lekoubou, Emma Y. Wu, Kinfe G. Bishu, Bruce Ovbiagele Source Type: research
Variability in Intensive Care Utilization for Intracerebral Hemorrhage in the United States: Retrospective Cohort Study
We examined whether ICU availability was a significant contributor to ICH outcomes by US geographic region.
Source: Journal of Stroke and Cerebrovascular Diseases - July 1, 2022 Category: Neurology Authors: David Daniel, Daniel Santos, Luke Maillie, Mandip S. Dhamoon Source Type: research
Functional Recovery in Patients with Acute Stroke and Pre-Existing Disability: A Natural History Study
One million strokes occur in the United States every year, with as many as 1 in 3 occurring among patients with a pre-existing disability.1,2 Though they are a significant portion of the stroke population, such patients are often excluded from interventional trials.3-5 As a result, acute ischemic stroke patients with pre-morbid disability are often omitted from clinical practice treatment guidelines, such as for mechanical thrombectomy (MT). In the latest American Heart Association (AHA) guidelines, MT is only indicated for patients with no pre-stroke disability, as defined by a modified Rankin scale (mRS) score of 0-1.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2022 Category: Neurology Authors: Nicholas Vigilante, Scott Kamen, Ryan Shannon, Lauren Thau, Miriam Butler, Solomon Oak, Linda Zhang, Taryn Hester, Jesse M. Thon, James E. Siegler Source Type: research
