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Total 1186 results found since Jan 2013.

Inflammatory markers in patients with hypertension
Br J Hosp Med (Lond). 2023 May 2;84(5):1-8. doi: 10.12968/hmed.2022.0531. Epub 2023 May 22.ABSTRACTHypertension is a chronic disease with high levels of morbidity and disability. Elevated blood pressure can lead to many complications and is the main risk factor for stroke, heart failure and nephropathy. Factors associated with hypertension and inflammatory response differ from those associated with vascular inflammation. The immune system plays a vital role in the pathophysiology of hypertension. Inflammation is particularly relevant in the progression of cardiovascular diseases, which has led to extensive research on infl...
Source: British Journal of Hospital Medicine - May 26, 2023 Category: Internal Medicine Authors: Chen Yihui Gong Yanfeng Source Type: research

How do we ensure that more patients receive stroke thrombectomy in the UK?
Br J Hosp Med (Lond). 2023 May 2;84(5):1-4. doi: 10.12968/hmed.2023.0111. Epub 2023 May 22.ABSTRACTStroke is a major cause of death in the UK. Mechanical thrombectomy is the most effective treatment for large vessel ischaemic strokes. Despite this, very few patients in the UK receive mechanical thrombectomy. This editorial explores the main barriers to mechanical thrombectomy use and mechanisms to improve uptake.PMID:37235673 | DOI:10.12968/hmed.2023.0111
Source: British Journal of Hospital Medicine - May 26, 2023 Category: Internal Medicine Authors: Richard J Jabbour Helen Routledge Nick Curzen Source Type: research

Identification of vulnerable carotid plaque with histologically validated CT-derived plaque maps
CONCLUSIONS: Carotid plaque components can be differentiated by CT using a ratio of plaque/contrast attenuation. CT-derived plaque map volumes of necrotic core help distinguished the most vulnerable plaques.ADVANCES IN KNOWLEDGE: CT-derived plaque maps based on plaque/contrast attenuation may provide new markers of carotid plaque vulnerability.PMID:37183910 | DOI:10.1259/bjr.20220982
Source: The British Journal of Radiology - May 15, 2023 Category: Radiology Authors: Daniel Rhys Obaid Ike Okonji Suk F Cheng Argyrios A Giannopoulos Pragash Kamalathevan Julian Halcox Manuel Rodriguez-Justo Toby Richards Source Type: research

When does life end? New organ donation strategy fuels debate
On a chilly holiday Monday in January 2020, a medical milestone passed largely unnoticed. In a New York City operating room, surgeons gently removed the heart from a 43-year-old man who had died and shuttled it steps away to a patient in desperate need of a new one. More than 3500 people in the United States receive a new heart each year. But this case was different—the first of its kind in the country. “It took us 6 months to prepare,” says Nader Moazami, surgical head of heart transplantation at New York University (NYU) Langone Health, where the operation took place. The run-up included oversight from an ethi...
Source: ScienceNOW - May 11, 2023 Category: Science Source Type: news

Forecasting feels-like temperatures as a strategy to reduce heat illnesses during sport events
Many athletes, amateur and professional alike, compete in and train for outdoor running events every year, and even more participate in outdoor sports in general. Many major sport events such as the Summer Olympic and Paralympic Games and World Championships take place in summer and mostly in the Northern Hemisphere. Therefore, athletes are often at risk of sustaining heat illnesses during heat extremes, which are exacerbated by climate change.1 Heat illnesses describe a group of pathologies ranging from relatively minor to very severe symptoms such as potentially fatal exertional heat stroke.2 3 The risk for heat illnesse...
Source: British Journal of Sports Medicine - May 2, 2023 Category: Sports Medicine Authors: Klöwer, M., Edouard, P., Niess, A. M., Racinais, S., Pitsiladis, Y. P., Pappenberger, F., Hollander, K. Tags: BJSM Editorial Source Type: research

Elevated Expression of miR-296 in Human Placentas and Serum Samples From Pregnancies With Preeclampsia
Conclusion: miR-296 may function as a putative diagnostic biomarker for PE and contribute to identifying at-risk mothers in pregnancy.PMID:37113621 | PMC:PMC10126236 | DOI:10.3389/bjbs.2023.11004
Source: British Journal of Biomedical Science - April 28, 2023 Category: Laboratory Medicine Authors: Dandan Zhu Ting Guo Jie Xu Donglan Yuan Mei Lin Minyan Yang Source Type: research

Barriers and enablers to healthcare system uptake of direct oral anticoagulants for stroke prevention in atrial fibrillation: a qualitative interview study with healthcare professionals and policy makers in England
Conclusions The findings contribute to the wider literature by providing a new and in-depth understanding on the uptake of DOACs. The findings may be applicable to other new medicines used in chronic health conditions.
Source: BMJ Open - April 25, 2023 Category: General Medicine Authors: Medlinskiene, K., Richardson, S., Petty, D., Stirling, K., Fylan, B. Tags: Open access, Qualitative research Source Type: research

Prediction of hemorrhagic transformation via pre-treatment CT radiomics in acute ischemic stroke patients receiving endovascular therapy
CONCLUSION: CT radiomics analysis is a valuable tool for predicting HT in AIS patients receiving EVT. It may guide the selection of patients in practice and improve procedural safety and effectiveness.ADVANCES IN KNOWLEDGE: Identification of the importance of pre-treatment CT radiomics in the prediction of HT in AIS patients after EVT.PMID:37086070 | DOI:10.1259/bjr.20220439
Source: The British Journal of Radiology - April 22, 2023 Category: Radiology Authors: Xuehua Wen Yanan Xiao Xingfei Hu Junfa Chen Fahuan Song Source Type: research

High-resolution vessel wall magnetic resonance imaging in intracranial vasculopathies: an experience from eastern India
CONCLUSION: Adjunctive use of HR-IVWI, to clinical and luminal assessment, can significantly improve diagnostic accuracy during evaluation of intracranial vasculopathies, with its greatest utility in diagnosing in ICAD, CNS angiitis and dissection.ADVANCES IN KNOWLEDGE: HR-IVWI allows clearer etiological distinction of intracranial vasculopathies having therapeutic and prognostic implications.PMID:37066831 | DOI:10.1259/bjr.20230114
Source: The British Journal of Radiology - April 17, 2023 Category: Radiology Authors: Shambaditya Das Mahmud Mossa-Basha Mousam Dey Avijit Hazra Alak Pandit Gautam Das Souvik Dubey Biman Kanti Ray Source Type: research