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Total 1186 results found since Jan 2013.
Macrocytosis in Mitochondrial DNA Deletion Syndromes
Acta Haematol. 2023 Feb 10. doi: 10.1159/000529311. Online ahead of print.ABSTRACTLarge single mtDNA (mitochondrial DNA) deletion syndrome is a rare inborn error of metabolism with variable heteroplasmy levels and clinical phenotype among affected individuals. Chronic progressive external ophthalmoplegia (CPEO) is the most common phenotype in adults with this form of mitochondrial disease [1-2]. The common CPEO clinical manifestations are ptosis and ophthalmoplegia. More variable phenotypic manifestations of CPEO (CPEO plus) include involvement of the peripheral nervous system and myopathy. Here, we describe a 62-year-old ...
Source: Acta Haematologica - February 12, 2023 Category: Hematology Authors: Farida Almarzooqi Hilary Vallance Michelle M Mezei Anna Lehman Gabriella Horvath Bojana Rakic Leslie Zypchen Andre Mattman Source Type: research
Cost-effectiveness of targeted screening for non-valvular atrial fibrillation in the United Kingdom in older patients using digital approaches
CONCLUSIONS: Screening for NVAF at ≥75 years of age could result in fewer NVAF-related strokes. NVAF screening is cost-effective and may be cost-saving depending on the program chosen.PMID:36757910 | DOI:10.1080/13696998.2023.2179210
Source: Journal of Medical Economics - February 9, 2023 Category: Health Management Authors: Shreeya Patel Thitima Kongnakorn Andreas Nikolaou Yassir Javaid Ruth Mokgokong Source Type: research
Atrial fibrillation in UK South Asian hospitalized ischemic stroke patients: The BRAINS study
by Taylor Aurelius, Gie Ken-Dror, Sapna D. Sharma, Sageet Amlani, Gunaratnam Gunathilagan, David L. Cohen, Chakravarthi Rajkumar, Stuart Maguire, Sissi Ispoglou, Ibrahim Balogun, Anthea Parry, Lakshmanan Sekaran, Hafiz Syed, Enas Lawrence, Ravneeta Singh, Ahamad Hassan, Chris Wharton, Khalid Javaid, Neetish Goorah, Peter Carr, Eman Abdus Sami, Pankaj Sharma
IntroductionSouth Asian diaspora comprise one of the largest ethnic minority groups in the world yet data about atrial fibrillation (AF) in this demographic is understudied. Our aim is to identify differences in AF prevalence and treatment between South Asians and white...
Source: PLoS One - February 7, 2023 Category: Biomedical Science Authors: Taylor Aurelius Source Type: research
Routine cerebral embolic protection in transcatheter aortic valve implantation: rationale and design of the randomised British Heart Foundation PROTECT-TAVI trial
EuroIntervention. 2023 Jan 26:EIJ-D-22-00713. doi: 10.4244/EIJ-D-22-00713. Online ahead of print.ABSTRACTTranscatheter aortic valve implantation (TAVI) is an established treatment for aortic stenosis. Cerebral embolic protection (CEP) devices may impact periprocedural stroke by capturing debris destined for the brain. However, there is a lack of high-quality randomised trial evidence supporting the use of CEP during TAVI. The British Heart Foundation (BHF) PROTECT-TAVI trial will address whether the routine use of CEP reduces the incidence of stroke in patients undergoing TAVI. BHF PROTECT-TAVI is a prospective, open-label...
Source: EuroIntervention - January 27, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Rajesh K Kharbanda Alexander David Perkins James Kennedy Adrian P Banning Andreas Baumbach Daniel J Blackman Matthew Dodd Richard Evans David Hildick-Smith Zahra Jamal Peter Ludman Stephen Palmer Rodney Stables Tim Clayton Source Type: research
Socioeconomic deprivation and post-stroke care in the community
Br J Gen Pract. 2023 Jan 26;73(727):56-57. doi: 10.3399/bjgp23X731781. Print 2023 Feb.NO ABSTRACTPMID:36702607 | DOI:10.3399/bjgp23X731781
Source: The British Journal of General Practice - January 26, 2023 Category: Primary Care Authors: Anna Pawlak Eugene Yee Hing Tang Source Type: research
