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Total 296 results found since Jan 2013.

Disability in Singapore's Elderly Population.
CONCLUSION: The findings highlighted specific factors associated with disability in this multiethnic population. The identification of these factors would lead the way to the development of appropriate interventions. PMID: 27523509 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - June 30, 2016 Category: Journals (General) Authors: Mahesh M, Abdin E, Vaingankar JA, Picco L, Jeyagurunathan A, Shafie SB, Pang S, Sagayadevan V, Seow E, Chong SA, Subramaniam M Tags: Ann Acad Med Singapore Source Type: research

Prevalence and Risk Factors of Caregiver Dependence among Older Adults in a Southeast Asian Population.
CONCLUSION: Various sociodemographic and health-related conditions were significantly associated with caregiver dependence. Dependent older adults will put greater demands on health and social services, resulting in greater healthcare expenditures. Hence, effective planning, services and support are crucial to meet the needs of dependent older adults and their caregivers. PMID: 27922142 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - October 31, 2016 Category: Journals (General) Authors: Picco L, Abdin E, Vaingankar JA, Pang S, Shafie S, Sambasivam R, Chong SA, Subramaniam M Tags: Ann Acad Med Singapore Source Type: research

Commentary on “Rehabilitation Outcomes Associated With Foreign Domestic Workers as Caregivers”
The purpose of this commentary is to illuminate the role of foreign domestic workers (FDW) as caregivers for patients undergoing rehabilitation in Asia. The authors of a published study in this issue of the Archives of Physical Medicine and Rehabilitation investigate the association between the characteristics of caregivers for patients recovering from sub-acute stroke and the rehabilitation outcomes of those patients in Singapore. The investigators examined over 4,000 caregivers and one of the findings showed that after controlling for characteristics of both caregivers and patients, there was a significant and negative a...
Source: Archives of Physical Medicine and Rehabilitation - May 27, 2017 Category: Rehabilitation Authors: Frances M. Yang, Solon T. Kao Tags: Commentary Source Type: research

Epidemiology of a Rare Event
Retinal emboli are rare, with a prevalence in most of the relatively few studies on the subject, to my knowledge, of approximately 1 in 100 adults and an even smaller annual incidence. The study by Cheung et al in the present issue ofJAMA Ophthalmology involves the multiethnic population of Singapore and found that retinal emboli were present in only 88 of 9978 individuals who had retinal photographs (0.9%). This randomly selected sample of adults aged 40 to 80 years comprised, in almost equal numbers, of members of the 3 major ethnic groups residing in Singapore: Chinese, Malay, and Indian. Cheung et al provided data rele...
Source: JAMA Ophthalmology - October 1, 2017 Category: Opthalmology Source Type: research

Outcomes of primary percutaneous coronary intervention in acute myocardial infarction due to unprotected left main thrombosis: The Asia ‐Pacific Left Main ST‐Elevation Registry (ASTER)
ConclusionsSTEMI from culprit unprotected left main coronary artery stenosis is associated with significant mortality and morbidity. Emergency PCI provides an important treatment option in this high‐risk group, but in‐hospital mortality remains high.
Source: Journal of Interventional Cardiology - November 16, 2017 Category: Cardiology Authors: Jonathan Yap, Gagan D. Singh, Jung ‐Sun Kim, Krishan Soni, Kelvin Chua, Alvin Neo, Choong Hou Koh, Ehrin J. Armstrong, Stephen W. Waldo, Kendrick A. Shunk, Reginald I. Low, Myeong‐Ki Hong, Yangsoo Jang, Khung Keong Yeo Tags: ORIGINAL INVESTIGATION Source Type: research

Glycaemic, Blood Pressure and Low Density Lipoprotein Cholesterol Control in Adult Patients with Diabetes in Singapore: A Review of Singapore Literature Over Two Decades.
CONCLUSION: Mirroring global patterns, the glycaemic, BP and LDL-C control in adult diabetic patients in Singapore do not appear to be treated to target in the majority of patients. PMID: 29177366 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - October 1, 2017 Category: General Medicine Authors: Poh Z, Venkataraman K, Toh SE, Low LL Tags: Ann Acad Med Singapore Source Type: research

Taste perception and diet in people of Chinese ancestry.
CONCLUSIONS: There was a salty-sour confusion among Singaporean Chinese unlike the bitter-sour confusion reported for Caucasians. Most sodium came from sauces and was added during food preparation. In programs to address sodium: potassium ratio excess among Chinese prone to hypertension and stroke, sour as well as salty taste may need to be considered. PMID: 29384339 [PubMed - in process]
Source: Asia Pacific Journal of Clinical Nutrition - February 2, 2018 Category: Nutrition Authors: Leong CS, Forde CG, Tey SL, Henry CJ Tags: Asia Pac J Clin Nutr Source Type: research

Characterisation of bone and joint infections due to Group B Streptococcus serotype III sequence type 283
This study adds to growing evidence of a distinct clinical presentation associated with ST283 GBS, involving predominantly healthier patients without significant comorbidities, and with distinct clinical manifestations with regard to bone and joint disease.
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 18, 2018 Category: Microbiology Source Type: research

The 2017 hormone therapy position statement of The North American Menopause Society
The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence. The Panel's recommendations were reviewed and approved by...
Source: Menopause - October 25, 2018 Category: OBGYN Tags: Commemorative Papers Source Type: research

External Validation of Hematoma Expansion Scores in Spontaneous Intracerebral Hemorrhage in an Asian Patient Cohort
ConclusionsTo our knowledge, this is the first study to validate HE scores, namely PREDICT, 9-Point and BRAIN, in a multi-ethnic Asian ICH patient population. The PREDICT score was the best performing model in our study cohort, based on the performance metrics employed in this study. Our findings also showed support for CT angiography spot sign as a predictor of outcome after ICH. Although the models assessed are sufficient for risk stratification, the discrimination and calibration are at best moderate and could be improved.
Source: Neurocritical Care - October 30, 2018 Category: Neurology Source Type: research

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Publication date: 10–16 November 2018Source: The Lancet, Volume 392, Issue 10159Author(s): Hmwe Hmwe Kyu, Degu Abate, Kalkidan Hassen Abate, Solomon M Abay, Cristiana Abbafati, Nooshin Abbasi, Hedayat Abbastabar, Foad Abd-Allah, Jemal Abdela, Ahmed Abdelalim, Ibrahim Abdollahpour, Rizwan Suliankatchi Abdulkader, Molla Abebe, Zegeye Abebe, Olifan Zewdie Abil, Victor Aboyans, Aklilu Roba Abrham, Laith Jamal Abu-Raddad, Niveen M E Abu-Rmeileh, Manfred Mario Kokou AccrombessiSummaryBackgroundHow long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading caus...
Source: The Lancet - November 11, 2018 Category: General Medicine Source Type: research

Light-Induced Pupillary Responses in Alzheimer's Disease
Light-Induced Pupillary Responses in Alzheimer's Disease Pratik S. Chougule1, Raymond P. Najjar1,2, Maxwell T. Finkelstein1, Nagaendran Kandiah3,4 and Dan Milea1,2,5* 1Department of Visual Neurosciences, Singapore Eye Research Institute, Singapore, Singapore 2The Ophthalmology & Visual Sciences ACP, Duke-National University of Singapore (NUS) Medical School, Singapore, Singapore 3Department of Neurology, National Neuroscience Institute, Singapore, Singapore 4Duke-National University of Singapore (NUS), Singapore, Singapore 5Singapore National Eye Centre, Singapore, Singapore The impact of Alzhe...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

The Young Male Syndrome —An Analysis of Sex, Age, Risk Taking and Mortality in Patients With Severe Traumatic Brain Injuries
Conclusion The willingness of young males to engage in dangerous situations might be adaptive in terms of fitness maximization. Nonetheless, for some individuals this intense sexual competition can be detrimental to health. The correspondence between the age distribution of the reproductively most active population and those suffering sTBI only partially supports the evolutionary hypothesis about risk-taking behavior. The prevalence of higher external mortality rates of young males, on the other hand, was not present in our data at all, nor did we find any support for the assumption that sTBI acquired from riskier behavio...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Nation-Wide Observational Study of Cardiac Arrests Occurring in Nursing Homes and Nursing Facilities in Singapore.
CONCLUSION: Neurological outcomes were poorer in NH survivors of OHCA. These findings should inform health policies on termination of resuscitation, advance care directives and do-not-resuscitate orders in this population. PMID: 32582905 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - April 30, 2020 Category: General Medicine Authors: Ho AF, Lee KY, Lin X, Hao Y, Shahidah N, Ng YY, Leong BS, Sia CH, Tan BY, Tay AM, Ng MX, Gan HN, Mao DR, Chia MY, Cheah SO, Ong ME Tags: Ann Acad Med Singapore Source Type: research

Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis
ConclusionsOur results do not support the hypothesis that higher ceramide concentrations are linked to higher CVD risk, but suggest that other classes of sphingolipids may affect CVD risk.
Source: Metabolomics - August 19, 2020 Category: Biology Source Type: research