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Warfarin adherence and anticoagulation control in atrial fibrillation patients: a systematic review
CONCLUSIONS: While the available evidence is limited, this systematic review demonstrated a positive finding of the association between warfarin adherence and anticoagulation control in patients with AF.PMID:34982455 | DOI:10.26355/eurrev_202112_27642
Source: European Review for Medical and Pharmacological Sciences - January 4, 2022 Category: Drugs & Pharmacology Authors: M Ababneh S A Nasser A Rababa'h F Ababneh Source Type: research

The Impact of Intravenous Iron Supplementation on Hematinic Parameters and Erythropoietin Requirements in Hemodialysis Patients
ConclusionHigh-dose intravenous iron (400  mg/week) can reduce the mean dose of rhEPO requirements and increase the TSAT index over a period of 6 months in hemodialysis patients. High-dose IV iron administration can decrease cardiovascular events in hemodialysis patients with iron deficiency anemia.
Source: Advances in Therapy - July 12, 2021 Category: Drugs & Pharmacology Source Type: research

Gastrointestinal Bleeding Associated With Warfarin and Rivaroxaban Therapy in Atrial Fibrillation Cases with Concomitant Coagulopathy.
CONCLUSION: The incidence of GI bleeding was lower in AF patients who received rivaroxaban compared to those treated with warfarin. Also, GI bleeding risk does not change according to the consumption of other anti-coagulant drugs and un-derlying history of hypertension or stroke in patients received rivaroxaban. Therefore, rivaroxaban is suggested as the choice of prophylaxis in patients with AF and concomitant coagulopathy. PMID: 33390152 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - January 5, 2021 Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research

The Effect of Allograft Transplantation of Sertoli Cell on Expression of NF- кB, Bax Proteins, ...
In this study, a remarkable decrease in neurological deficits, infection, blood-brain barrier permeability, and brain edema was observed in the cell transplant recipient group in comparison with the ischemia group. Probably, a reduction in inflammation (NF-кB factor) an d apoptosis (Bax) following injection of Sertoli cells result in amelioration of ischemic damages induced by MCAO surgery.
Source: Iranian Journal of Pharmaceutical Research - June 8, 2020 Category: Drugs & Pharmacology Source Type: research

The effect of Allograft Transplantation of Sertoli Cell on Expression of NF- кB, Bax Proteins, ...
In this study, a remarkable decrease in neurological deficits, infection, blood-brain barrier permeability, and brain edema was observed in the cell transplant recipient group in comparison with the ischemia group. Probably, a reduction in inflammation (NF-кB factor) an d apoptosis (Bax) following injection of Sertoli cells result in amelioration of ischemic damages induced by MCAO surgery.
Source: Iranian Journal of Pharmaceutical Research - May 27, 2020 Category: Drugs & Pharmacology Source Type: research

The Potential Effect of Intravenous Calcitriol on the Ischemia-Reperfusion Injury and ...
Conclusion: Administration of calcitriol in patients with non-ST-segment elevation acute coronary syndromes undergoing elective PCI can attenuate the increase in serum inflammatory biomarkers in the serum (hs-CRP and hs-IL-6) and thus decrease the inflammatory reaction caused by PCI.
Source: Iranian Journal of Pharmaceutical Research - February 28, 2020 Category: Drugs & Pharmacology Source Type: research

Evaluation of neuroprtective effects of L-Carnitine and Fat emulsion in the CVA patients: a ...
Stroke was the second most frequent cause of death after coronary artery disease. The purpose of this study was to evaluate the effects of L-carnitine and Intralipid Fat emulsion alone and in combination in patients with ischemic stroke. In a prospective, RCT, and double-blind study 100 patients with MCA ischemic cerebrovascular accident who were admitted in the first 24 hours of injury entered the study. Patients were randomly assigned into four groups of L-carnitine, Fat emulsion, L-carnitine plus Fat emulsion and control. 500 ml of Fat emulsion 10% was infused over 6 to 12 hours and 1 gr of l-carnitine was given orally ...
Source: Iranian Journal of Pharmaceutical Research - January 31, 2020 Category: Drugs & Pharmacology Source Type: research

The Potential Effect of Intravenous Calcitriol on the Ischemia-Reperfusion Injury and ...
Conclusion: Administration of calcitriol in patients with non-ST-segment elevation acute coronary syndromes undergoing elective PCI can attenuate the increase in serum inflammatory biomarkers in the serum (hs-CRP and hs-IL-6) and thus decrease the inflammatory reaction caused by PCI.
Source: Iranian Journal of Pharmaceutical Research - November 30, 2019 Category: Drugs & Pharmacology Source Type: research

Tenecteplase versus reteplase in acute myocardial infarction: A network meta-analysis of ...
Conclusions: Indirect comparison suggests similar efficacy and safety of tenecteplase and reteplase. Hence, the use of each one of the two medicines depends on price, facility, and accessibility of the medicine.
Source: Iranian Journal of Pharmaceutical Research - June 30, 2019 Category: Drugs & Pharmacology Source Type: research

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