The Effect of Allograft Transplantation of Sertoli Cell on Expression of NF- кB, Bax Proteins, ...

In this study, a remarkable decrease in neurological deficits, infection, blood-brain barrier permeability, and brain edema was observed in the cell transplant recipient group in comparison with the ischemia group. Probably, a reduction in inflammation (NF-кB factor) an d apoptosis (Bax) following injection of Sertoli cells result in amelioration of ischemic damages induced by MCAO surgery.
Source: Iranian Journal of Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research