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Population-based assessment of cardiovascular complications of rheumatic heart disease in Fiji: a record-linkage analysis
Conclusions Our study defines the burden of RHD-attributable morbidity in the general population of Fiji, potentially reflecting the situation in low-income and middle-income countries worldwide. Hospitalisation for an RHD complication is associated with markedly increased risk of death, re-emphasising the importance of effective early prevention.
Source: BMJ Open - April 24, 2023 Category: General Medicine Authors: Parks, T., Narube, L., Perman, M. L., Sakumeni, K., Fong, J. J., Engelman, D., Colquhoun, S. M., Steer, A. C., Kado, J. Tags: Open access, Cardiovascular medicine Source Type: research

In Vivo Vasospasm Induction by Ultrasound Application in the Chicken Chorioallantoic Membrane Model
In this study, we assessed the reliability of in vivo vasospasm induction by ultrasound application in the chicken chorioallantoic membrane (CAM) model. After incubation of fertilized chicken eggs for four days, a fenestration was performed to enable examination of the CAM vessels. On the thirteenth day, continuous-wave ultrasound (3  MHz, 1 W/cm2) was applied on the CAM vessels for 60  s. The ultrasound effect on the vessels was recorded by life imaging (5-MP HD-microscope camera, Leica®). The induced vessel diameter changes were evaluated in a defined time interval of 20 min using a Fiji macro. The vessel diameter b...
Source: Translational Stroke Research - January 21, 2022 Category: Neurology Source Type: research

A Multicentre Study Comparing Cerebrovascular Disease Profiles in Pacific Islander and Caucasian Populations Presenting with Stroke and Transient Ischaemic Attack
Conclusion: Distinct cerebrovascular disease profiles are identifiable in PI-born patients who present with TIA or stroke symptoms in Australia. These may be used in the future to direct targeted approaches to stroke prevention and care in culturally and linguistically diverse populations.Neuroepidemiology
Source: Neuroepidemiology - December 1, 2021 Category: Epidemiology Source Type: research

Estimation of total glomerular number using an integrated disector method in embryonic and postnatal kidneys
Abstract Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) are a polymorphic group of clinical disorders comprising the major cause of renal failure in children. Included within CAKUT is a wide spectrum of developmental malformations ranging from renal agenesis, renal hypoplasia and renal dysplasia (maldifferentiation of renal tissue), each characterized by varying deficits in nephron number. First presented in the Brenner Hypothesis, low congenital nephron endowment is becoming recognized as an antecedent cause of adult-onset hypertension, a leading cause of coronary heart disease, stroke, and renal f...
Source: Canadian Journal of Kidney Health and Disease - June 17, 2014 Category: Urology & Nephrology Source Type: research

Australia faces increased risk of disease from climate change, reports find
A number of recent studies have shown a clear connection between a warming planet and increased health risksAustralia has been warned of the rising threat of dengue fever and heat stroke deaths in the wake of a study that found climate change is aiding the spread of infectious diseases around the world. The report, part-funded by the US National Science Foundation and published in Science, found that climate change is already abetting diseases in wildlife and agriculture, with humans at heightened risk from dengue fever, malaria and cholera. Wealthy countries will do much better at predicting and tackling new disease threa...
Source: Guardian Unlimited Science - August 2, 2013 Category: Science Authors: Oliver Milman Tags: theguardian.com News Climate change Environment Australia Source Type: news