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Intracerebral Hemorrhage Among Blood Donors and Their Transfusion Recipients
CONCLUSIONS AND RELEVANCE: In an exploratory analysis of patients who received red blood cell transfusions, patients who underwent transfusion with red blood cells from donors who later developed multiple spontaneous ICHs were at significantly increased risk of spontaneous ICH themselves. This may suggest a transfusion-transmissible agent associated with some types of spontaneous ICH, although the findings may be susceptible to selection bias and residual confounding, and further research is needed to investigate if transfusion transmission of cerebral amyloid angiopathy might explain this association.PMID:37698562 | DOI:1...
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Jingcheng Zhao Klaus Rostgaard Elsa Lauwers Torsten Dahl én Sisse Rye Ostrowski Christian Erikstrup Ole Birger Pedersen Bart de Strooper Robin Lemmens Henrik Hjalgrim Gustaf Edgren Source Type: research

Migraine and risk of premature myocardial infarction and stroke among men and women: A Danish population-based cohort study
by Cecilia Hvitfeldt Fuglsang, Lars Pedersen, Morten Schmidt, Jan P. Vandenbroucke, Hans Erik B øtker, Henrik Toft Sørensen BackgroundMigraine carries risk of myocardial infarction (MI) and stroke. The risk of premature MI (i.e., among young adults) and stroke differs between men and women; previous studies indicate that migraine is mainly associated with an increased risk of stroke among young women. The aim of this study was to examine impact of migraine on the risk of premature (age ≤60 years) MI and ischemic/hemorrhagic stroke among men and women. Methods and findingsUsing Danish medical registries, we conducted a ...
Source: PLoS Medicine - June 13, 2023 Category: Internal Medicine Authors: Cecilia Hvitfeldt Fuglsang Source Type: research

Treatment patterns for oral anticoagulants in older patients with atrial fibrillation: a retrospective, cross-sectional, nationwide study from Denmark
Conclusion In this large nationwide study, we found that in older patients with AF, the overall rates of OAC prescription were generally high (~80%) and increasing during the last decade. Factors associated with not receiving guideline recommended OAC treatment were generally related to bleeding risk factors or frailty.
Source: BMJ Open - September 1, 2022 Category: General Medicine Authors: Rasmussen, P. V., Sakthivel, T., Dalgaard, F., Gislason, G. H., Pallisgaard, J. L., Hansen, M. L. Tags: Open access, Cardiovascular medicine Source Type: research

Atrial fibrillation, liver cirrhosis, thrombosis, and bleeding: A  Danish population-based cohort study
CONCLUSION: In patients with AFF, liver cirrhosis was associated with an elevated risk of ischemic stroke, venous thromboembolism, and all evaluated bleeding complications.PMID:35229067 | PMC:PMC8867136 | DOI:10.1002/rth2.12668
Source: Thrombosis and Haemostasis - March 1, 2022 Category: Hematology Authors: Emil B Riahi Kasper Adelborg Lars Pedersen S øren R Kristensen Anette T Hansen Henrik T S ørensen Source Type: research

Incidence of stroke, transient ischaemic attack and determinants of poststroke mortality among immigrants in Denmark, 2004-2018: a population-based cohort study
Conclusions The age-standardised risk of stroke and TIA was significantly higher among the majority of immigrants than Danish-born individuals. Interventions that reduce the burden of comorbidities, improve acute stroke care and target sociodemographic factors may address the higher risk of poststroke mortality among immigrants.
Source: BMJ Open - October 21, 2021 Category: General Medicine Authors: Mkoma, G. F., Johnsen, S. P., Iversen, H. K., Andersen, G., Norredam, M. Tags: Open access, Neurology Source Type: research

Risk of delirium and impaired neurological outcome associated with delay in neurorehabilitation after acquired brain injury
CONCLUSIONS In this study, mortality and neurological outcome were comparable with those reported in similar studies. Waiting for transfer to another facility due to capacity significantly impairs neurological outcome and increases delirium. FUNDING none. TRIAL REGISTRATION not relevant.PMID:34558409
Source: Danish Medical Journal - September 24, 2021 Category: General Medicine Authors: Peter Martin Hansen J ørgen Trankjær Lauridsen Nicole Sb Frandsen Source Type: research

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