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Condition: Atrial Fibrillation
Countries: Canada Health

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Total 200 results found since Jan 2013.

Approach to atrial fibrillation: Essentials for primary care
CONCLUSION: Most patients with AF can be managed effectively in primary care. Family physicians not only play an important role in ensuring patients with AF receive timely diagnoses, but they are also key to providing initial and ongoing care, especially in patients with comorbid conditions.PMID:37072207 | PMC:PMC10112727 | DOI:10.46747/cfp.6904245
Source: Canadian Family Physician Medecin de Famille Canadien - April 18, 2023 Category: Primary Care Authors: Alan Bell Jason G Andrade Laurent Macle Kim A Connelly Lisa LaBine Alexander G Singer Source Type: research

Quality of anticoagulant control and patient experience associated with long-term warfarin in Canadian patients with non-valvular atrial fibrillation: A multicentre, prospective study
ConclusionsWe showed excellent overall TTR in an observed Canadian cohort, with monitoring through a dedicated anticoagulant clinic being associated with a statistically and clinically significant improvement in TTR. The burden of warfarin therapy on patients ’ health related quality of life or daily work and activities was low.
Source: PLoS One - April 18, 2023 Category: Biomedical Science Authors: Rita Selby Source Type: research

Family Physician Prescribing Practices and Perspectives on Shared Decision-Making Regarding the Use of Oral Anticoagulants for Stroke Prevention in Patients 75  Years or Older With Atrial Fibrillation
CONCLUSION: Family physicians strongly consider patient risks and utilize risk-assessment tools when initiating OAC in older adults with AF. Despite all physicians reporting the use of shared decision-making and that their patients were educated on the indications for OAC, confidence in initiating treatment was variable. Further exploration into factors impacting physician confidence is needed.PMID:36960556 | DOI:10.1177/21501319231164060
Source: Primary Care - March 24, 2023 Category: Primary Care Authors: Jahaan Ali Reza Abbasi-Dezfouly Sheny Khera Paul Kivi Peter George Jaminal Tian Source Type: research

A Cost-Effectiveness Analysis of Biomarkers for Risk Prediction in Atrial Fibrillation
ConclusionPM compared to SOC is economically dominant and is projected to generate cost savings.
Source: Molecular Diagnosis and Therapy - January 31, 2023 Category: Molecular Biology Source Type: research

Impact of Rabeprazole on APO-Dabigatran Exposure in Healthy Volunteers
CONCLUSIONS: When APO-dabigatran is administered with rabeprazole, the exposure to dabigatran is reduced by about 30%, which is similar to the level observed with Pradaxa when it was co-administered with a proton pump inhibitor. However, the finding that one-third of participants had a > 50% reduction in exposure is concerning, and it highlights the need for caution in patients who have, or are at risk of, reduced gastric acidity.PMID:36700178 | PMC:PMC9869351 | DOI:10.1016/j.cjco.2022.09.006
Source: Atherosclerosis - January 26, 2023 Category: Cardiology Authors: Noel Chan Matt Wheeler Vinai Bhagirath Jacqueline Bosch Jutta Heinrich-Nols Debbie Sloane Joanne van Ryn Linda Jefferies Jacqueline Wilkinson Qilong Yi John Eikelboom Source Type: research

Self-reported adherence to direct oral anticoagulants versus warfarin therapy in a specialized thrombosis service —a cross-sectional study of patients in a Canadian Health Region
ConclusionsSelf-reported medication adherence was similar between warfarin and DOACs. Since suboptimal adherence is associated with poor clinical outcomes and increased costs, various stakeholders should emphasize the importance of medication adherence to oral anticoagulants at each patient encounter.
Source: European Journal of Clinical Pharmacology - November 18, 2022 Category: Drugs & Pharmacology Source Type: research

Starting anticoagulation for atrial fibrillation in the emergency department safely
Atrial fibrillation (AF) is a common morbidity, which is increasing in prevalence.1 AF predisposes patients to stroke while anticoagulation therapy reduces the stroke risk in this population. The proportion of patients with AF receiving oral anticoagulation is one of the pan-Canadian quality indicators set by the Canadian Cardiovascular Society.2 Our review of local ED practice identified that only 17% of patients with AF eligible for anticoagulation were being prescribed an anticoagulant.3 We implemented a simple ED pathway for initiating anticoagulation in patients with AF in four EDs. The pathway was available for emerg...
Source: Emergency Medicine Journal - October 21, 2022 Category: Emergency Medicine Authors: Kirwan, C., Ramsden, S., Carter, J., Tong, X. C., Huang, J., Clayton, N., McArthur, R., Kibria, A., de Wit, K. Tags: Research letter Source Type: research

Geographic and temporal variation in the treatment and outcomes of atrial fibrillation: a population-based analysis of national quality indicators
The objective of this study was to assess for potential geographic variation in the quality of atrial fibrillation care in Alberta, Canada.METHODS: In a population-based cohort of adults (age ≥ 18 yr) with incident nonvalvular atrial fibrillation (NVAF) diagnosed between Apr. 1, 2008, and Mar. 31, 2016, in Alberta, we investigated the variation in national quality indicators of atrial fibrillation care developed by the Canadian Cardiovascular Society. Specifically, we assessed the geographic and temporal variation in the proportion of patients with initiation of oral anticoagulant therapy, persistence with therapy, ische...
Source: cmaj - August 2, 2022 Category: General Medicine Authors: Derek S Chew Flora Au Yuan Xu Braden J Manns Marcello Tonelli Stephen B Wilton Brenda Hemmelgarn Shiying Kong Derek V Exner Amity E Quinn Source Type: research