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Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis
CONCLUSIONS: Recruitment targets were reached, but many eligible participants declined randomization. There were numerically more bleeding events in patients taking rivaroxaban compared with control, but rates of bleeding and recurrent venous thromboembolism were low overall and in keeping with previous studies. Participants had symptoms affecting their well-being at enrollment but improved over time.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT03178864.PMID:37675613 | DOI:10.1161/STROKEAHA.123.044113
Source: Atherosclerosis - September 7, 2023 Category: Cardiology Authors: Thalia S Field Vanessa Dizonno Mohammed A Almekhlafi Fouzi Bala Ibrahim Alhabli Hubert Wong Monica Norena Maria Karina Villaluna Princess King-Azote Namali Ratnaweera Steven Mancini Stephen C Van Gaal Laura K Wilson Brett R Graham Luciano A Sposato Dylan Source Type: research

EVT Will Save Millions of Lives From Stroke. Eventually.
A procedure called EVT is creating radically better outcomes for patients, but only when it ’s performed quickly enough — and that requires the transformation of an entire system of care.
Source: NYT Health - March 1, 2023 Category: Consumer Health News Authors: Eva Holland Tags: Stroke Emergency Medical Treatment Hemorrhagic Stroke Stents (Medical Devices) Catheters Brain Alberta (Canada) Bangladesh Source Type: news

Association of body mass index with COVID-19-related neurologic sequelae: a retrospective cohort study
This study demonstrates the absence of an association between BMI and neurologic manifestations following acute COVID-19 illness. Prospective studies using standardized data collection tools and direct measures of body fat are warranted to obtain more valid effect estimates.
Source: Clinical and Experimental Medicine - December 16, 2022 Category: Research Source Type: research

Estimated pulse-wave velocity predicts survival in patients requiring extracorporeal membrane oxygenation
CONCLUSIONS: ePWV is a promising marker for risk-stratification in ECMO patients. Further investigation is required to better delineate the role of arterial health assessment in disease trajectory and strengthen the validity of AS as a marker of interest in medical and surgical management.PMID:36419384 | DOI:10.1177/02676591221141963
Source: Perfusion - November 24, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Mohsyn I Malik Dave Nagpal Source Type: research

Characterising methamphetamine use to inform health and social policies in Manitoba, Canada: a protocol for a retrospective cohort study using linked administrative data
Introduction Rising use of methamphetamine is causing significant public health concern in Canada. The biological and behavioural effects of methamphetamine range from wakefulness, vigour and euphoria to adverse physical health outcomes like myocardial infarction, haemorrhagic stroke, arrhythmia and seizure. It can also cause severe psychological complications such as psychosis. National survey data point to increasing rates of methamphetamine use, as well as increasing ease of access and serious methamphetamine-related harms. There is an urgent need for evidence to address knowledge gaps, provide direction to harm reducti...
Source: BMJ Open - October 19, 2022 Category: General Medicine Authors: Nickel, N. C., Enns, J. E., Freier, A., McCulloch, S. C., Chartier, M., Casidsid, H. J. M., Balogun, O. D., Mulhall, D., Dragan, R., Sarkar, J., Bolton, J., Konrad, G., Phillips-Beck, W., Sanguins, J., Shimmin, C., McDonald, N., Mignone, J., Hinds, A., Me Tags: Open access, Public health Source Type: research

Consider alternative causes before allocating acute ischaemic stroke to COVID-19
We read with interest the excellent article by Dmytriw et al reported on a retrospective, multicenter cohort study of patients with COVID-19 with acute ischaemic stroke (AIS) admitted to stroke units in the USA and Canada between March and August 2020.1 The primary endpoint was a modified Rankin Scale (mRS) of 5–6 and the secondary endpoints were an mRS<3, ordinal RS, symptomatic intracerebral haemorrhage and complications during hospitalisation.1 It has been established that there may be an association between COVID-19-associated AIS and severe outcome or death, and that the neutrophil to lymphocyte ratio predict...
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 14, 2022 Category: Neurosurgery Authors: Finsterer, J. Tags: COVID-19 PostScript Source Type: research

Relationships between long-term residential exposure to total environmental noise and stroke incidence
CONCLUSION: The results suggest that total environmental noise is associated with incident stroke, which is consistent with studies on transportation noise and other CVD.PMID:35900388 | DOI:10.4103/nah.nah_34_21
Source: Noise and Health - July 28, 2022 Category: Audiology Authors: Larisa I Yankoty Philippe Gamache C éline Plante Sophie Goudreau Claudia Blais St éphane Perron Michel Fournier Martina S Ragettli Marianne Hatzopoulou Ying Liu Audrey Smargiassi Source Type: research

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