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Condition: Ischemic Stroke
Countries: Canada Health
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Total 362 results found since Jan 2013.
Dual Antiplatelet Therapy in Minor Stroke/Transient Ischemic Attack - An Updated Network Meta-Analysis
Can J Neurol Sci. 2023 Sep 11:1-12. doi: 10.1017/cjn.2023.287. Online ahead of print.NO ABSTRACTPMID:37694524 | DOI:10.1017/cjn.2023.287
Source: The Canadian Journal of Neurological Sciences - September 11, 2023 Category: Neurology Authors: Ronda Lun Gabriele Zitikyte Danielle Carole Roy Shan Dhaliwal Dar Dowlatshahi Source Type: research
Impact of body mass index on efficacy and safety of ticagrelor versus clopidogrel in patients with minor stroke or transient ischemic attack
CMAJ. 2023 Jul 10;195(26):E897-E904. doi: 10.1503/cmaj.230262.ABSTRACTBACKGROUND: Body mass index (BMI) may affect the response to platelet P2Y12 receptor inhibitors. We aimed to explore whether BMI influenced the efficacy and safety of ticagrelor and clopidogrel for secondary prevention of minor ischemic stroke or transient ischemic attack (TIA) among patients enrolled in the CHANCE-2 (Ticagrelor or Clopidogrel with Aspirin in High-Risk Patients with Acute Nondisabling Cerebrovascular Events II) trial.METHODS: In a multicentre, randomized, double-blind, placebo-controlled trial, conducted in China, we randomized patients ...
Source: Canadian Medical Association Journal - July 10, 2023 Category: General Medicine Authors: Jia Zhang Anxin Wang Xue Tian Xia Meng Xuewei Xie Jing Jing Jinxi Lin Yilong Wang Zixiao Li Liping Liu Hao Li Yong Jiang Xingquan Zhao Yongjun Wang Source Type: research
Oral probiotic therapy improves motor function in a rodent model of sensorimotor stroke
In this study, we examined the effect of post-stroke oral probiotic therapy on motor behavior in the pre-clinical mouse endothelin-1 (ET-1) model of sensorimotor stroke. We found that post-stroke oral probiotic therapy with Cerebiome® (Lallemand, Montreal, Canada), containing B. longum R0175 and L. helveticus R0052, improved functional recovery and changed the composition of the post-stroke gut microbiota. Interestingly, oral Cerebiome® administration did not result in alterations of lesion volume or the number of CD8+/Iba1+ cells in the injured tissue. Overall, these findings suggest that probiotic treatment following i...
Source: Brain Research - June 26, 2023 Category: Neurology Authors: E Daniele Y Nazer I Kortebi D Lozano Casasbuenas Y Fan M Trinh T A Tompkins M Faiz Source Type: research
