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Total 481 results found since Jan 2013.

The Man Who Grew Eyes
The train line from mainland Kobe is a marvel of urban transportation. Opened in 1981, Japan’s first driverless, fully automated train pulls out of Sannomiya station, guided smoothly along elevated tracks that stand precariously over the bustling city streets below, across the bay to the Port Island. The island, and much of the city, was razed to the ground in the Great Hanshin Earthquake of 1995 – which killed more than 5,000 people and destroyed more than 100,000 of Kobe’s buildings – and built anew in subsequent years. As the train proceeds, the landscape fills with skyscrapers. The Rokkō mounta...
Source: Healthy Living - The Huffington Post - October 11, 2015 Category: Consumer Health News Source Type: news

Diffuse Fluid-Attenuated Inversion Recovery Hyperintensity in Subarachnoid Space Following Cerebral Angiography and Intravenous Thrombolysis
Transient cortical blindness (TCB) is a relatively rare but well-recognized complication following cardiovascular and cerebral angiography.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2015 Category: Neurology Authors: Ramin Zand, Shailesh Male, John K. Lynch Tags: Case Studies Source Type: research

Disrupting Today's Healthcare System
This week in San Diego, Singularity University is holding its Exponential Medicine Conference, a look at how technologists are redesigning and rebuilding today's broken healthcare system. Healthcare today is reactive, retrospective, bureaucratic and expensive. It's sick care, not healthcare. This blog is about why the $3 trillion healthcare system is broken and how we are going to fix it. First, the Bad News: Doctors spend $210 billion per year on procedures that aren’t based on patient need, but fear of liability. Americans spend, on average, $8,915 per person on healthcare – more than any other count...
Source: Healthy Living - The Huffington Post - November 9, 2015 Category: Consumer Health News Source Type: news

Study of the lipidemic profile of diabetic patients. Negative correlation of cholesterol levels of diabetes type I patients with serum amylase concentration.
Authors: Eleftheriou P, Tseka E, Varaga E, Nasiou M, Sampanis C, Zografou I, Oulorgia J, Damontsidou K, Zaimi T, Markou HI, Varsamidis K, Petrou C, Limberaki E, Ganou CJ Abstract Diabetes Mellitus type I (DM1) and II (DM2) share the common characteristic of high blood glucose concentration and the health complications resulting from uncontrolled hyperglycemia such as hyperlipidemia, cardiovascular problems, stroke, ketoacidosis, kidney failure and blindness but have different etiology. DM1 is practically an autoimmune disease. Genetic susceptibility together with environmental factors leads to disease development. ...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Updated NICE guidelines on the management of type 2 diabetes in adults
Updated NICE guidelines stress the need for individualising care for people with type 2 diabetes, and include new recommendations on managing blood glucose, effective drug treatments and lifestyle interventions. The vast majority of people who have diabetes have type 2 diabetes, a form of the condition that tends to appear in people over 40, but that is increasingly being seen in younger people due to rising obesity levels. The condition is also common among people from people from African, African Caribbean and South Asian family origins. It can result in blindness, kidney failure, premature heart disease strok...
Source: Society for Endocrinology - December 2, 2015 Category: Endocrinology Source Type: news

“Walk the Rim, Feel the Bone” Technique in Superior Sulcus Filling
This study describes an injection technique that minimizes the risk of blindness and includes a case study demonstrating the cosmetic benefits of this procedure. To avoid retrograde injection of filler embolus into the ophthalmic artery, we advocate a “‘walk the rim, feel the bone” approach. Small boluses of hyaluronic acid filler are given in preperiosteal plane, avoiding the superior orbital foramen.
Source: Plastic and Reconstructive Surgery Global Open - December 1, 2015 Category: Cosmetic Surgery Tags: Case Report Source Type: research

Superiority trials: statistical trickery or mass blindness?
Non-inferiority trials are conducted to demonstrate whether a new treatment is not inferior to an existing treatment by more than a prespecified margin, known as the non-inferiority margin (). is thus a critical element in these studies and must be justifiable both statistically and clinically.1 We have recently argued that there should be a superiority margin similar to the non-inferiority margin in superiority trials.2 The current practice is that if 95% CI lies within the inferiority margin () of the no-difference line, the drug is considered to be non-inferior. The drug is considered inferior only if the 95% CI lie out...
Source: Postgraduate Medical Journal - January 25, 2016 Category: Journals (General) Authors: Shafiq, N., Malhotra, S. Tags: Letter Source Type: research

Id: 64: reversible blindness associated with diabetic ketoacidosis: a rare combination
Discussion Sudden painless vision loss has a wide differential diagnosis and it is usually caused by ischemia at retinal, ocular or cortical level. No history of methanol ingestion or trauma, normal fundoscopy, normal MRI and rapid return of vision after correction of diabetic ketoacidosis strongly suggests that blindness was related to acidosis. Alcoholic ketoacidosis has been reported to cause transient reversible blindness in other case reports and correction of acidosis lead to reversal of blindness. Other rare causes of reversible blindness include posterior reversible encephalopathy syndrome, brain tumors, anterior i...
Source: Journal of Investigative Medicine - March 21, 2016 Category: Research Authors: Asad, Z., Chaudhary, A., Awab, A. Tags: Pulmonary/Critical Care Source Type: research

Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome.
In conclusion, this is the first report of a biological effect of the coding SNPs in the LOXL1 gene associated with PEX syndrome, on the LOXL1 protein. The findings indicate that the disease associated coding variants themselves may be involved in the manifestation of PEX syndrome. PMID: 26997634 [PubMed - as supplied by publisher]
Source: Experimental Eye Research - March 16, 2016 Category: Opthalmology Authors: Sharma S, Martin S, Sykes MJ, Dave A, Hewitt AW, Burdon KP, Ronci M, Voelcker NH, Craig JE Tags: Exp Eye Res Source Type: research

The Number Of Adults With Diabetes Has Quadrupled To 422 Million
By Kate Kelland LONDON (Reuters) - The number of adults with diabetes has quadrupled worldwide in under four decades to 422 million, and the condition is fast becoming a major problem in poorer countries, a World Health Organization study showed on Wednesday. In one of the largest studies to date of diabetes trends, the researchers said ageing populations and rising levels of obesity across the world mean diabetes is becoming "a defining issue for global public health". Type 2 diabetes is a long-term condition characterized by insulin resistance. Patients can manage their diabetes with medication and diet, but the disease ...
Source: Science - The Huffington Post - April 6, 2016 Category: Science Source Type: news

Diabetes Increases Four-Fold Worldwide
GENEVA (AP) — Excessive weight, obesity, aging and population growth drove a nearly four-fold increase in worldwide cases of diabetes over the last quarter-century, affecting 422 million people in 2014, the World Health Organization reported Wednesday. In a new report on diabetes, the U.N. health agency called for stepped-up measures to reduce risk factors for diabetes and improve treatment and care that has ballooned in recent years alongside an increase in obesity rates. WHO said 8.5 percent of the world population had diabetes two years ago, up from 108 million, or 4.7 percent, in 1980. On Wednesday, WHO Director-Ge...
Source: JEMS: Journal of Emergency Medical Services News - April 7, 2016 Category: Emergency Medicine Tags: General News Diabetes & Endocrine Disorders Source Type: news

Different Clinical Manifestations of MELAS in a Single Family (P5.073)
Conclusions: In 1992, diagnostic criteria for MELAS included symptom onset prior to 40-years of age. Numerous case reports have found patients presenting with MELAS after age 40 with genetic confirmation of the mutation. Today, the criteria have been eased and a diagnosis of MELAS should be considered in the appropriate clinical setting at any age.Disclosure: Dr. Koshy has nothing to disclose. Dr. Kamins has nothing to disclose. Dr. Mishra has nothing to disclose. Dr. Flippen has received personal compensation in an editorial capacity for the Journal of Graduate Medical Education and UpToDate. Dr. Singh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Koshy, S., Kamins, J., Mishra, S., Flippen, C., Singh, S. Tags: Hereditary Muscle Diseases: Genetics and Phenotype Source Type: research

Variability in Approach to Treatment of Acute Central Retinal Artery Occlusion in US Teaching Hospitals (S47.006)
CONCLUSIONS: There is currently no consensus on how patients with acute CRAO should be managed and there is resulting wide variability in treatment trends. We propose an evidence-based protocol for acute management of these patients.Disclosure: Dr. Schrag has nothing to disclose. Dr. Youn has nothing to disclose. Dr. Patrylo has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Lavin has nothing to disclose. Dr. Kirshner has nothing to disclose. Dr. Greer has received personal compensation for activities with Bard Medical. Dr. Greer has received personal compensation in an editorial capacity for Seminars in Neurology.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Schrag, M., Youn, T., Patrylo, M., Schindler, J., Lavin, P., Kirshner, H., Greer, D. Tags: IV-tPA and Endovascular Therapy Source Type: research