• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Antegrade axillary arterial perfusion in 3D endoscopic minimally-invasive mitral valve surgery
CONCLUSION: Selective use of antegrade axillary artery perfusion in patients with systemic atherosclerosis shows similar in-hospital outcomes as compared to lower risk patients undergoing retrograde femoral perfusion. Patients with higher perioperative risk and severe atherosclerosis can be safely treated via the minimally invasive approach with antegrade axillary perfusion.PMID:36247481 | PMC:PMC9561617 | DOI:10.3389/fcvm.2022.980074
Source: Atherosclerosis - October 17, 2022 Category: Cardiology Authors: Johannes Petersen Shiho Naito Benjamin Kloth Simon Pecha Svante Zipfel Yousuf Alassar Christian Detter Lenard Conradi Hermann Reichenspurner Evaldas Girdauskas Source Type: research

Cell-Based Therapies for Stroke: Promising Solution or Dead End? Mesenchymal Stem Cells and Comorbidities in Preclinical Stroke Research
Conclusion The high prevalence of comorbidities in patients with stroke indicates the need for therapies in preclinical studies that take into account these comorbidities in order to avoid failures in translation to the patient. Preclinical studies are beginning to evaluate the efficacy of MSC treatment in stroke associated with comorbidities, especially hypertension, for ischemic and hemorrhagic stroke. Regarding aging and diabetes, only ischemic stroke studies have been performed. For the moment, few studies have been performed and contradictory results are being reported. These contradictory results may be due to the u...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Early Results of Surgical Simultaneous Therapy for Significant Carotid Artery Stenosis and Heart Disease.
Conclusion Simultaneous coronary bypass grafting as a single procedure or in combination with valve replacement and endarterectomy of severe carotid lesions with or without patients' history of previous stroke can be performed with a calculated low surgical risk. The complication rate for neurologic and myocardial events is low compared with the hazard of a single surgical repair. The in-hospital mortality is not significantly different to isolated procedures. The concomitant appearance of coronary stenosis and carotid artery disease is reasonable due to the nature of arteriosclerosis. In our opinion these patients benef...
Source: The Thoracic and Cardiovascular Surgeon - April 5, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Irqsusi M, Vannucchi A, Beckers J, Kasseckert S, Waldhans S, Vogt S, Moosdorf RG Tags: Thorac Cardiovasc Surg Source Type: research

Early Results of Surgical Simultaneous Therapy for Significant Carotid Artery Stenosis and Heart Disease
Conclusion Simultaneous coronary bypass grafting as a single procedure or in combination with valve replacement and endarterectomy of severe carotid lesions with or without patients' history of previous stroke can be performed with a calculated low surgical risk. The complication rate for neurologic and myocardial events is low compared with the hazard of a single surgical repair. The in-hospital mortality is not significantly different to isolated procedures. The concomitant appearance of coronary stenosis and carotid artery disease is reasonable due to the nature of arteriosclerosis. In our opinion these patients benef...
Source: The Thoracic and Cardiovascular Surgeon - April 5, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Irqsusi, Marc Vannucchi, Alessandro Beckers, Julius Kasseckert, Stefan Waldhans, Stefan Vogt, Sebastian Moosdorf, Rainer G. H. Tags: Original Cardiovascular Source Type: research

EphrinB2 Activation Enhances Vascular Repair Mechanisms and Reduces Brain Swelling After Mild Cerebral Ischemia.
CONCLUSIONS: We show that reducing swelling could result in improved outcome because of reduction in damaged brain tissue. We also identify a novel role for ephrinB2/EphB4 signaling in the maintenance of the neurovascular homeostasis and provide a novel therapeutic approach in reducing brain swelling after stroke. PMID: 28254815 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 1, 2017 Category: Cardiology Authors: Ghori A, Freimann FB, Nieminen-Kehlä M, Kremenetskaia I, Gertz K, Endres M, Vajkoczy P Tags: Arterioscler Thromb Vasc Biol Source Type: research

2016 Russell Ross Memorial Lecture in Vascular Biology: Molecular-Cellular Mechanisms in the Progression of Atherosclerosis.
Abstract Atherosclerosis is initiated by the subendothelial accumulation of apoB-containing lipoproteins, which initiates a sterile inflammatory response dominated by monocyte-macrophages but including all classes of innate and adaptive immune cells. These inflammatory cells, together with proliferating smooth muscle cells and extracellular matrix, promote the formation of subendothelial lesions or plaques. In the vast majority of cases, these lesions do not cause serious clinical symptoms, which is due in part to a resolution-repair response that limits tissue damage. However, a deadly minority of lesions progres...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - December 14, 2016 Category: Cardiology Authors: Tabas I Tags: Arterioscler Thromb Vasc Biol Source Type: research