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Condition: Antiphospholipid Syndrome

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Total 523 results found since Jan 2013.

Malignant Isolated Cortical Vein Thrombosis as the Initial Manifestation of Primary Antiphospholipid Syndrome: Lessons on Diagnosis and Management From a Case Report
ConclusionICoVT is a rare yet potentially fatal manifestation of APS, and its diagnosis and treatment are extremely challenging. Timely diagnosis, prompt treatment, and close monitoring are essential to improve the clinical prognosis of patients with APS-related ICoVT.
Source: Frontiers in Immunology - April 25, 2022 Category: Allergy & Immunology Source Type: research

Data from New VOYAGER PAD Analyses at ACC.22 Reinforce Benefit of XARELTO ® (rivaroxaban) Plus Aspirin in Patients with Peripheral Artery Disease (PAD) and Various Co-Morbid Conditions
RARITAN, N.J., April 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from new analyses from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefit of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) in reducing severe vascular events in patients with PAD after lower-extremity revascularization (LER), a procedure that restores blood flow to the legs. Data from the two analyses demonstrate the role that the XARELTO® vascular dose plays in PAD patients with and without chronic kidney disease (CKD) and in PAD patients with and ...
Source: Johnson and Johnson - April 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Cerebral Infarction due to Severe ADAMTS-13 Deficiency with Normal Hematological Parameters: A Cause of Cryptogenic Stroke
Stroke is a leading cause of death and disability worldwide, and there are 1.3 million strokes annually in adults less than 50 years old.1 Many of these strokes are cryptogenic, with no clear etiology identified. In this setting clinicians frequently test for rare causes of thrombosis including hyperhomocystinemia, antiphospholipid syndrome, Factor V Leiden, prothrombin gene mutations, and protein C, S or antithrombin deficiency. Thrombotic thrombocytopenic purpura (TTP) causes arterial thrombosis, but is rarely considered in the evaluation of cryptogenic stroke with normal or near-normal hematologic profiles.
Source: Journal of Stroke and Cerebrovascular Diseases - March 16, 2022 Category: Neurology Authors: Andrew Matthews, Jennifer Yui, Elaine Y. Chiang, Allyson M. Pishko, Adam Cuker, Brett L. Cucchiara, Donna George, Farzana Sayani, Michael T. Mullen Tags: Short Communication Source Type: research

COVID-19's Clinical-Pathological Evidence in Relation to Its Repercussion on the Central and Peripheral Nervous System
CONCLUSION: The neurological implications of COVID-19 range from initial symptoms, such as headache, to serious complications, such as ischemic stroke. Although the pathogenesis of neurological phenomena requires further studies, targeted management of the patient is feasible, considering agility in recognizing the infection. Therefore, medical precaution and clinical reasoning are emphasized when providing services to the patient.PMID:35137375 | DOI:10.1007/978-3-030-85113-2_11
Source: Advances in Experimental Medicine and Biology - February 9, 2022 Category: Research Authors: Amanda Menezes Morgado Ana Luiza Menezes Santana Bezerra Esther Barbosa Gon çalves Felix Jos é Correia Saraiva Júnior Nat ália Bitú Pinto Modesto Leite Rolim Neto Ana Lu íza de Aguiar Rocha Martin Source Type: research

Height associated with different clinical expressions in primary antiphospholipid syndrome female patients
CONCLUSIONS: This study used a systematic design to show that different heights in individuals with pAPS are associated with different diseases' expressions. When analyzing females exclusively, the taller ones were younger, heavier with more venous events, and more minor strokes than the smaller ones.PMID:35113434 | DOI:10.26355/eurrev_202201_27885
Source: European Review for Medical and Pharmacological Sciences - February 3, 2022 Category: Drugs & Pharmacology Authors: J Freire Carvalho M B Pereira Torales M I Figueiredo Sousa T Larocca Skare Source Type: research