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Transgender venous thrombosis
A 53-year-old male-to-female transgender patient on cross-sex hormone replacement therapy (CSHT), estradiol 8 mg daily, presented to the emergency department (ED) with acute-onset headache and left visual field disturbances after a recent mechanical fall with head trauma. The medical history was notable for hyperlipidemia. There was no personal or family history of clotting disorders and no history of tobacco use.
Source: Neurology Clinical Practice - December 11, 2017 Category: Neurology Authors: Opaskar, A., Scharf, E. L., Chilungu, M. W., Kelly, A. G. Tags: All Cerebrovascular disease/Stroke, Cerebral venous thrombosis Case Source Type: research

Multiple Cerebral Infarctions in a Patient with Adenomyosis on Hormone Replacement Therapy: A Case Report
A 59-year-old woman was admitted to our hospital because of repeated episodes of bilateral hand weakness. She had a 10-year history of combined estrogen –progestin therapy for menopausal symptoms. Magnetic resonance imaging on admission showed multiple hyperintense lesions in bilateral cerebral and cerebellar cortices on diffusion-weighted imaging. Transesophageal echocardiography showed thrombus formation on the aortic valve and moderate aortic i nsufficiency. Laboratory test demonstrated elevated CA125 (334.8 U/mL) and D-dimer (7.0 µg/mL) levels.
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2016 Category: Neurology Authors: Nanako Hijikata, Yuki Sakamoto, Chikako Nito, Noriko Matsumoto, Arata Abe, Akane Nogami, Takahiro Sato, Hiroyuki Hokama, Seiji Okubo, Kazumi Kimura Tags: Case Studies Source Type: research

Hormone Replacement Therapy and Adverse Outcomes in Women With Atrial Fibrillation: An Analysis From the Atrial Fibrillation Follow-Up Investigation of Rhythm Management Trial Brief Reports
Conclusions— HRT does not independently predict mortality, thromboembolism, or bleeding in a large cohort of women with atrial fibrillation.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Apostolakis, S., Sullivan, R. M., Olshansky, B., Lip, G. Y. H. Tags: Other Treatment Brief Reports Source Type: research