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Specialty: General Medicine
Condition: Thrombosis

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Total 639 results found since Jan 2013.

A review of decision support, risk communication and patient information tools for thrombolytic treatment in acute stroke: lessons for tool developers
Conclusions: Tools to support decision making or patient understanding in the treatment of acute stroke with thrombolysis have been sub-optimally developed. Development of tools should utilise mixed methods and strategies to meaningfully involve clinicians, patients and their relatives in an iterative design process; include evidence-based methods to augment interpretability of textual and probabilistic information (e.g. graphical displays showing natural frequencies) on the full range of outcome states associated with available options; and address patients with different levels of health literacy. Implementation of tools...
Source: BMC Health Services Research - June 18, 2013 Category: Journals (General) Authors: Darren FlynnGary FordLynne StobbartHelen RodgersMadeleine MurtaghRichard Thomson Source Type: research

Correspondence Intermittent pneumatic compression in patients with stroke
We read with great interest the Article by the CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration (Aug 10, p 516) that assessed intermittent pneumatic compression (IPC) in immobile patients with acute stroke. Patients were allocated to receive either IPC or no IPC. The authors conclude that IPC is an effective method of reducing the risk of deep vein thrombosis (DVT) and possibly improving survival in patients who are immobile after stroke.
Source: LANCET - November 2, 2013 Category: Journals (General) Authors: Johann Auer, Robert Berent, Franz Gurtner Tags: Correspondence Source Type: research

Intervention for Acute Stroke
In Reply In our recent article, we reviewed major thrombolytic stroke trials and a pooled meta-analysis that confirmed favorable clinical outcome at 3 months if intravenous recombinant tissue plasminogen activator (rtPA) was provided between 3 and 4.5 hours of symptom onset. However, because the majority of patients were contributed by a single European trial, the European Cooperative Acute Stroke Study (ECASS-3), we were careful to state that “… in the 3- to 4.5-hour window, rtPA is recommended for patients with moderately severe symptoms younger than 80 years and without contraindications in some guidelines for stroke management.”
Source: JAMA - August 11, 2015 Category: Journals (General) Source Type: research

Left atrial myxoma in a patient with atrial fibrillation following ischemic stroke – Case report
Conclusions In case of ischemic stroke and atrial fibrillation in subjects over the age of 60 years myxoma should be considered as a potential cause of these clinical conditions.
Source: Polish Annals of Medicine - March 28, 2016 Category: Journals (General) Source Type: research

Real World Stroke Prevention Strategies in Nonvalvular Atrial Fibrillation in Patients with Renal Impairment
ConclusionRAMSES study showed that one‐third of the patients with NVAF had RI in the real‐world setting. Although it is mandatory in most of the patients with concomitant NVAF and RI, nearly one‐third of these patients did not receive any anticoagulant therapy.This article is protected by copyright. All rights reserved.
Source: European Journal of Clinical Investigation - April 13, 2017 Category: Journals (General) Authors: , Kadir U ğur Mert, Gurbet Özge Mert, Özcan Başaran, Osman Beton, Volkan Dogan, Mehmet Tekinalp, Ahmet Çağrı Aykan, Ezgi Kalaycıoğlu, Ismail Bolat, Onur Taşar, Özgen Şafak, Macit Kalçık, Mehmet Yaman, Cevat Kırma, Murat Biteker Tags: Original Article Source Type: research

Real ‐world stroke prevention strategies in nonvalvular atrial fibrillation in patients with renal impairment
ConclusionRAMSES study showed that one‐third of the patients with NVAF had RI in the real‐world setting. Although it is mandatory in most of the patients with concomitant NVAF and RI, nearly one‐third of these patients did not receive any anticoagulant therapy.
Source: European Journal of Clinical Investigation - May 16, 2017 Category: General Medicine Authors: Kadir U. Mert, Gurbet Ö. Mert, Özcan Başaran, Osman Beton, Volkan Dogan, Mehmet Tekinalp, Ahmet Ç. Aykan, Ezgi Kalaycıoğlu, Ismail Bolat, Onur Taşar, Özgen Şafak, Macit Kalçık, Mehmet Yaman, Cevat Kırma, Murat Biteker, Tags: Original Article Source Type: research

Successful thrombolytic therapy with recombinant tissue plasminogen activator in ischemic stroke after idarucizumab administration for reversal of dabigatran: a case report
ConclusionsIntravenous thrombolytic therapy with recombinant tissue plasminogen activator after reversal of dabigatran with idarucizumab may be safe and feasible in patients with acute ischemic stroke with lacunar infarct. Furthermore, intravenous thrombolytic therapy with recombinant tissue plasminogen activator could be used in patients in emergency settings until just before the end of the recommended time limit within which it needs to be administered because of the immediate effect of idarucizumab.
Source: Journal of Medical Case Reports - December 25, 2019 Category: General Medicine Source Type: research

Role of platelet gene polymorphisms in ischemic pediatric stroke subtypes: a case-control study.
CONCLUSION: Individual HPAs, and particularly HPA haplotypes, are involved in IPS subtypes pathogenesis. A possible risk-inducing synergistic effect of SELP haplotypes with FV R506Q is restricted to PAIS only. PMID: 32118374 [PubMed - in process]
Source: Croatian Medical Journal - February 28, 2020 Category: General Medicine Authors: Čeri A, Leniček Krleža J, Coen Herak D, Miloš M, Pavić M, Barišić N, Đuranović V, Zadro R Tags: Croat Med J Source Type: research

Clinical Risk Factors Associated with Ambulatory Outcome in Acute Ischemic Stroke Patients Smokers Treated with Thrombolytic Therapy
CONCLUSION: Our findings suggest that elderly smokers with atrial fibrillation would benefit more from aggressive management of atrial fibrillation than non-smokers.PMID:34077707 | DOI:10.1016/j.amjms.2021.01.028
Source: The American Journal of the Medical Sciences - June 2, 2021 Category: General Medicine Authors: Adeola Awujoola Patrick Sodeke Odebunmi Olufeyisayo Moboni Mokikan Emanuel Adeyemi Grace Babalola Oluwatosin Awujoola Marvin Okon Thomas I Nathaniel Source Type: research

Prevalence of left atrial appendage thrombus in patients with acute ischaemic stroke and sinus rhythm: a cross-sectional study
Conclusions In patients with AIS and sinus rhythm on 12-lead ECG, our study revealed that the prevalence of LAA thrombus was 6.7% with the most prevalent aetiology being paroxysmal AF. The presence of SEC can be a predictor of LAA thrombus in these patients.
Source: BMJ Open - December 17, 2021 Category: General Medicine Authors: Nguyen, H. T., Nguyen, H. V. B., Nguyen, H. Q., Le, H. Q. Tags: Open access, Cardiovascular medicine Source Type: research

Antithrombotic treatment after stroke due to intracerebral haemorrhage
CONCLUSIONS: We did not identify beneficial or hazardous effects of short-term prophylactic dose parenteral anticoagulation and long-term oral antiplatelet therapy after ICH on important outcomes. Although there was a significant reduction in MACE and all major occlusive vascular events after long-term treatment with therapeutic dose oral anticoagulation for atrial fibrillation after ICH, the pooled estimates were imprecise, the certainty of evidence was only moderate, and effects on other important outcomes were uncertain. Large RCTs with a low risk of bias are required to resolve the ongoing dilemmas about antithrombotic...
Source: Cochrane Database of Systematic Reviews - January 26, 2023 Category: General Medicine Authors: Alexia Cochrane Chen Chen Jacqueline Stephen Ole Morten R ønning Craig S Anderson Graeme J Hankey Rustam Al-Shahi Salman Source Type: research

A rare mechanism of embolic stroke complicating coronary thrombus aspiration
We report a case of embolic stroke complicating coronary thrombus aspiration in a 62-year-old man. Aspiration thrombectomy during percutaneous coronary intervention migrated thrombus to the proximal right coronary artery (RCA), and the thrombus was subsequently released into the aorta by backflow of the contrast injection causing aspiration thrombectomy-associated stroke. This is an extremely rare mechanism by which complications arise from failed aspiration thrombectomy.
Source: Clinical Case Reports - February 22, 2023 Category: General Medicine Authors: Reiko Shiomura, Hideki Miyachi, Takeshi Yamamoto, Hitoshi Takano Tags: CASE REPORT Source Type: research

Pheochromocytoma causing cardiomyopathy, ischemic stroke and acute arterial thrombosis: a case report and review of the literature.
We present a case of multiple, rare clinical complications of pheochromocytoma occurring in the same patient and the review of literature of these complications. PMID: 23513638 [PubMed - indexed for MEDLINE]
Source: Connecticut Medicine - February 1, 2013 Category: Journals (General) Authors: Vindenes T, Crump N, Casenas R, Wood K Tags: Conn Med Source Type: research